Product image of Meropur (Menotrophin) supplied by GNH India

Meropur

Active Ingredient:
Menotrophin
Origin:
EU

Meropur (Menotrophin)

Menotropin, the active ingredient in Meropur, is a gonadotropin presented as a sterile solution for subcutaneous use. It provides combined FSH and LH activity to treat infertility due to anovulation and to support assisted reproductive technology protocols in women.

GNH India supplies Meropur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution, ensuring product integrity from manufacturing to end‑user.

Manufacturer / TM Owner

Ferring S.P.A.

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Indications & Clinical Uses

  • Meropur (menotropin) is used in fertility treatment to stimulate ovarian follicular development.
  • Infertility due to anovulation: stimulates follicular growth and induces ovulation in women who do not ovulate spontaneously.
  • Assisted reproductive technology (ART) cycles: enhances controlled ovarian stimulation for procedures such as IVF.
  • In vitro fertilization (IVF) treatment: increases the number of mature oocytes retrieved during egg collection.

How It Works

  • Menotropin contains equal amounts of follicle‑stimulating hormone (FSH) and luteinizing hormone (LH). After subcutaneous injection it binds to FSH and LH receptors on ovarian granulosa and theca cells, activating intracellular signaling that promotes follicular maturation, estrogen production, and final oocyte release. The combined activity mimics the natural pituitary surge, coordinating the growth and ovulation of multiple follicles.

Side Effects

Menotropin may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Injection site pain or erythema
  • Abdominal bloating or discomfort
  • Headache
  • Nausea or mild gastrointestinal upset

Serious or Rare Side Effects

  • Ovarian hyperstimulation syndrome (OHSS)
  • Multiple pregnancy
  • Severe allergic reaction (anaphylaxis)
  • Thromboembolic events

Precautions & Warnings

  • When using Menotropin, clinicians should observe several safety considerations to minimize risks.
  • Monitor ovarian response: perform ultrasound and estradiol measurements to adjust dose.
  • Avoid use in pregnancy: the drug is intended for pre‑conception ovarian stimulation.
  • Use cautiously in hormone‑sensitive cancers: FSH/LH may stimulate tumor growth.
  • Assess for ovarian cysts: pre‑existing cysts increase risk of complications.
  • Adjust dose in renal or hepatic impairment: consider reduced dosing and close monitoring.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Menotropin can interact with other medications, influencing its efficacy or safety profile.

Major Interactions (Avoid)

  • Concurrent use with other gonadotropins: may cause excessive ovarian stimulation.
  • Estrogen‑containing oral contraceptives during stimulation: can blunt response and increase OHSS risk.
  • Simultaneous GnRH agonist therapy: may lead to unpredictable hormone levels.

Moderate Interactions (Monitor Closely)

  • Anticoagulants (e.g., warfarin): increased risk of ovarian bleeding.
  • Corticosteroids: may alter hormone metabolism.
  • Thyroid hormone replacement: monitor thyroid function as ovarian activity changes.

Frequently Asked Questions

Meropur contains menotropin, a gonadotropin that is used to stimulate ovarian follicular development in women with infertility due to anovulation and to support controlled ovarian stimulation in assisted reproductive technology protocols such as in‑vitro fertilisation.

Menotropin provides equal amounts of follicle‑stimulating hormone (FSH) and luteinizing hormone (LH). After subcutaneous injection it binds to FSH and LH receptors on ovarian cells, triggering signalling pathways that promote follicle growth, estrogen production and the final release of a mature oocyte.

The dose of Meropur is individualized. A qualified prescriber determines the amount, frequency and duration of treatment based on the patient’s ovarian response, the specific assisted‑reproduction protocol and other clinical factors.

Meropur is intended for use before conception to stimulate ovulation. It is not used during an established pregnancy, and safety in breastfeeding has not been established. Women should discuss reproductive plans with their healthcare provider before starting therapy.

To order Meropur, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if required) and any necessary import documentation.

Meropur delivers a fixed combination of FSH and LH activity, whereas some alternatives provide only FSH (e.g., recombinant FSH) or separate LH preparations. The combined profile can simplify dosing for protocols that require both hormones, but the choice depends on the clinician’s protocol, patient response and cost considerations.

Meropur should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. Keep it in the original packaging until use to maintain stability and potency.

Meropur is supplied as a sterile solution for subcutaneous injection. The injection is typically given into the abdominal wall or thigh, following aseptic technique and the dosing schedule prescribed by the treating physician.

The most serious risks include ovarian hyperstimulation syndrome (OHSS), which can cause abdominal pain, fluid accumulation and, in severe cases, thromboembolic events, as well as the possibility of multiple pregnancy and rare severe allergic reactions. Patients should be monitored closely for these complications.

Meropur is contraindicated in women who are already pregnant, have known hypersensitivity to menotropin or any excipients, have active ovarian cysts, or have hormone‑sensitive malignancies unless specifically advised by a specialist. It should also be used with caution in patients with severe renal or hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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