Metacam

Active Ingredient:: Meloxicam
Brand:: Metacam
Origin:: European Union

Metacam (Meloxicam)

Meloxicam, the active ingredient in Metacam, is a non‑steroidal anti‑inflammatory drug presented as a tablet for oral use. It is employed to relieve pain and reduce inflammation in conditions such as osteoarthritis and rheumatoid arthritis in adult patients and improve joint function under medical supervision.

GNH India supplies Metacam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures consistent quality and regulatory compliance across multiple regions. We partner with accredited manufacturers to provide reliable access to essential medicines.

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Indications & Clinical Uses

Metacam (meloxicam) is used to manage pain and inflammation associated with several musculoskeletal disorders.

Osteoarthritis: reduces joint pain and improves mobility.
Rheumatoid arthritis: decreases inflammation and joint damage.
Acute musculoskeletal pain: provides rapid analgesia.
Post‑operative pain: helps control postoperative discomfort.

How It Works

Meloxicam inhibits cyclooxygenase enzymes (COX‑1 and COX‑2) with greater selectivity for COX‑2, leading to decreased conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it lowers inflammatory mediators, thereby diminishing pain, swelling, and fever associated with inflammatory conditions. The preferential COX‑2 inhibition spares platelet function, which may reduce gastrointestinal toxicity compared with non‑selective NSAIDs, while still providing effective anti‑inflammatory activity.

Side Effects

Meloxicam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

Gastrointestinal upset: nausea, abdominal discomfort, or dyspepsia that may be transient.
Headache: mild to moderate intensity, often resolving without intervention.
Dizziness: transient sensation of light‑headedness, especially when standing quickly.
Edema: mild peripheral swelling, usually of the lower extremities.

Serious or Rare Side Effects

Gastrointestinal ulceration or bleeding: potentially life‑threatening lesions in the stomach or intestines.
Cardiovascular events: increased risk of myocardial infarction or cerebrovascular accident, particularly with long‑term use.
Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, requiring immediate medical attention.

Precautions & Warnings

When prescribing meloxicam, clinicians should consider several safety precautions to minimize risk.

Renal function: assess baseline kidney function and monitor in patients with renal impairment.
Gastrointestinal risk: avoid in patients with active peptic ulcer disease or a history of serious GI bleeding.
Cardiovascular health: use cautiously in individuals with uncontrolled hypertension or known cardiovascular disease.
Pregnancy and lactation: safety not established; avoid use during pregnancy unless clearly needed.
Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Meloxicam can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

Anticoagulants (e.g., warfarin): increased risk of bleeding.
High‑dose aspirin or other NSAIDs: additive gastrointestinal toxicity.
Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding risk.

Moderate Interactions (Monitor Closely)

ACE inhibitors or ARBs: may reduce renal function when combined.
Diuretics: potential for decreased renal perfusion and electrolyte imbalance.

Frequently Asked Questions

Metacam contains meloxicam, an NSAID that is commonly prescribed to relieve pain and reduce inflammation. It is indicated for conditions such as osteoarthritis, rheumatoid arthritis, acute musculoskeletal pain, and postoperative discomfort, helping patients improve mobility and quality of life.

Meloxicam works by inhibiting cyclooxygenase enzymes, especially COX‑2, which reduces the synthesis of prostaglandins—key mediators of inflammation, pain, and fever. This selective inhibition lowers inflammatory responses while preserving some COX‑1 activity, potentially decreasing gastrointestinal side effects compared with non‑selective NSAIDs.

The appropriate dose of Metacam is determined by a qualified prescriber based on the patient’s condition, age, weight, and renal or hepatic function. Healthcare professionals follow local guidelines and adjust the regimen as needed; patients should follow the prescribing information provided by their doctor.

Safety of meloxicam during pregnancy and lactation has not been established. It is generally advised to avoid use in pregnant or nursing women unless the potential benefit outweighs the risk, and only under direct medical supervision.

To order Metacam, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with non‑selective NSAIDs, meloxicam offers greater COX‑2 selectivity, which may reduce the incidence of gastrointestinal irritation while still delivering effective analgesic and anti‑inflammatory action. However, cardiovascular and renal risks remain similar to other NSAIDs, so individual patient factors guide drug selection.

Metacam should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and heat sources. Ensure the container is tightly closed to maintain stability and protect it from accidental contamination.

Metacam is typically supplied as an oral tablet that should be swallowed whole with a glass of water. It is taken with or without food, according to the prescriber’s instructions, and the dosing schedule is individualized for each patient.

The most serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, severe skin reactions like Stevens‑Johnson syndrome, and renal impairment. Patients should be monitored closely for signs of these conditions, and therapy should be discontinued if they occur.

Metacam is contraindicated in patients with known hypersensitivity to meloxicam or other NSAIDs, active gastrointestinal ulceration, severe heart failure, uncontrolled hypertension, and those who have experienced previous serious cardiovascular or renal events related to NSAID use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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Metacam (Meloxicam)

Indications & Clinical Uses

How It Works