Product image of Metafen (Paracetamol) supplied by GNH India

Metafen

Active Ingredient:
Paracetamol
Origin:
EU

Metafen (Paracetamol)

Paracetamol, the active ingredient in Metafen, is a Non‑opioid analgesic presented as a tablet for oral use. It treats fever and mild to moderate pain in adults and children when appropriate.
GNH India supplies Metafen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Metafen (Paracetamol) works as an analgesic and antipyretic across common pain‑and‑fever pathways.
  • Fever: reduces elevated body temperature associated with infection or inflammation.
  • Headache: alleviates mild to moderate headache symptoms.
  • Musculoskeletal pain: eases sore muscles and joint discomfort.
  • Dental pain: provides relief after dental procedures or toothache.

How It Works

  • Paracetamol acts centrally by inhibiting cyclooxygenase enzymes, primarily COX‑2, which lowers prostaglandin synthesis in the brain and spinal cord. This reduction diminishes the perception of pain and resets the hypothalamic temperature set‑point, producing antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea or stomach discomfort.
  • Mild rash or itching.
  • Headache.
  • Dizziness.
  • Elevated liver enzymes (asymptomatic).

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Acute liver failure, especially with overdose.
  • Blood disorders like thrombocytopenia.
  • Anaphylaxis or severe allergic reactions.

Precautions & Warnings

Use Metafen with awareness of specific safety considerations.

  • Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional.
  • Liver health: avoid use in patients with severe hepatic impairment.
  • Alcohol consumption: limit alcohol intake while using this product.
  • Pediatric use: follow age‑appropriate dosing guidelines.
  • Pregnancy and breastfeeding: consult a physician before use.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding.
  • Carbamazepine, phenytoin, or rifampicin: may reduce paracetamol effectiveness.
  • High‑dose alcohol: heightened liver toxicity.

Moderate Interactions (Monitor Closely)

  • Other hepatotoxic drugs (e.g., isoniazid, methotrexate).
  • Oral contraceptives: may slightly increase plasma levels.
  • Certain antiepileptics: may alter metabolism.
  • Antifungal agents like fluconazole: potential increase in exposure.

Frequently Asked Questions

Metafen contains paracetamol, which is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever associated with common infections. It is an over‑the‑counter option for short‑term symptom management.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, decreasing the production of prostaglandins that signal pain and regulate body temperature. This central action provides analgesic and antipyretic effects without strong peripheral anti‑inflammatory activity.

The appropriate dose of Metafen is determined by a prescriber or according to the product labeling. Dosage depends on the patient’s age, weight, and clinical condition, and should never exceed the maximum daily amount recommended for paracetamol.

Paracetamol is generally considered compatible with pregnancy and breastfeeding when used at recommended doses, but a healthcare professional should be consulted before use to confirm safety based on individual health status and any other medications.

To order Metafen, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metafen (paracetamol) differs from NSAIDs such as ibuprofen by lacking significant anti‑inflammatory activity and having a lower risk of gastrointestinal irritation. It is also non‑opioid, making it a safer option for patients who need analgesia without the risks associated with opioid medications.

Metafen should be stored at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and out of reach of children to maintain product stability and potency.

Metafen is taken orally, usually with a glass of water. It can be taken with or without food, but if stomach upset occurs, it may be helpful to take it with a small amount of food.

The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin rash develop.

Metafen should be avoided by individuals with known hypersensitivity to paracetamol, severe liver disease, or those who have exceeded the recommended daily dose. Patients on certain medications, such as warfarin or strong enzyme inducers, should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.