Product image of Metamizol Ababor (Metamizole Magnesium) supplied by GNH India

Metamizol Ababor

Active Ingredient:
Metamizole Magnesium
Origin:
EU

Metamizol Ababor (Metamizole Magnesium)

Metamizole Magnesium, the active ingredient in Metamizol Ababor, is a pyrazolone presented as an oral dosage form for oral use. It is employed to relieve pain, reduce fever, and alleviate visceral spasm in adult patients.
GNH India supplies Metamizol Ababor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ababor Pharmaceuticals, S.L.

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Indications & Clinical Uses

  • Metamizole Magnesium is used within the analgesic, antipyretic and spasmolytic therapeutic class to manage several common conditions.
  • Pain relief: provides effective analgesia for moderate to severe pain.
  • Fever reduction: lowers elevated body temperature in febrile states.
  • Visceral spasm: relaxes smooth‑muscle spasm of the gastrointestinal tract.

How It Works

  • Metamizole Magnesium inhibits cyclooxygenase enzymes, leading to reduced prostaglandin synthesis. This action diminishes peripheral sensitisation and central pain transmission. In addition, the compound exerts a central analgesic effect and relaxes smooth muscle, contributing to its antipyretic and spasmolytic properties.

Side Effects

Metamizole Magnesium may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea or vomiting
  • Dizziness or light‑headedness
  • Mild hypotension
  • Transient skin rash
  • Headache

Serious or Rare Side Effects

  • Agranulocytosis (dangerously low white‑blood‑cell count)
  • Severe cutaneous adverse reactions such as Stevens‑Johnson syndrome
  • Anaphylactic shock
  • Hepatic dysfunction
  • Blood dyscrasias including thrombocytopenia

Precautions & Warnings

  • When prescribing Metamizole Magnesium, clinicians should consider several safety measures.
  • Assess renal and hepatic function before initiation.
  • Monitor complete blood counts regularly during therapy.
  • Use with caution in patients with known hypersensitivity to pyrazolones.
  • Avoid in individuals with severe infection or bone‑marrow suppression.
  • Adjust dosing in elderly patients or those with comorbidities.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Metamizole Magnesium can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX inhibitors: heightened gastrointestinal toxicity.
  • Methotrexate: potential for enhanced toxicity.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: additive hypotensive effect.
  • Lithium: possible rise in serum lithium levels.
  • CYP450 inhibitors or inducers: may alter drug metabolism and plasma concentrations.

Frequently Asked Questions

Metamizol Ababor contains Metamizole Magnesium, which is employed to relieve moderate to severe pain, lower elevated body temperature, and relax visceral smooth‑muscle spasms. It is commonly prescribed in adult patients when a non‑opioid analgesic, antipyretic, or spasmolytic is required.

The drug blocks cyclooxygenase enzymes, reducing the synthesis of prostaglandins that mediate pain, fever, and inflammation. In addition, it acts centrally to diminish pain perception and exerts a direct spasmolytic effect on smooth muscle, providing relief from visceral cramps.

The appropriate dose is determined by the prescribing clinician based on the patient’s condition, age, weight, and renal or hepatic function. Dosage regimens are individualized and should follow the prescriber’s instructions and local regulatory guidelines.

Safety data for Metamizole Magnesium in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metamizole Magnesium belongs to the pyrazolone class, offering analgesic, antipyretic and spasmolytic effects, whereas ibuprofen is a non‑steroidal anti‑inflammatory drug (NSAID) primarily targeting inflammation and pain. Metamizole may be chosen when stronger analgesia or spasm relief is needed, but it carries a distinct risk profile, including rare blood‑cell disorders.

The product should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Ensure the container is tightly closed to maintain stability and prevent degradation.

Metamizol Ababor is intended for oral administration. The tablets or oral formulation should be swallowed whole with an adequate amount of water, unless otherwise directed by a healthcare professional.

The most critical adverse events include agranulocytosis, which can lead to severe infections, life‑threatening skin reactions such as Stevens‑Johnson syndrome, and anaphylaxis. Patients should be monitored for signs of infection, rash, or allergic reactions, and therapy should be discontinued immediately if these occur.

Metamizol Ababor is contraindicated in individuals with known hypersensitivity to Metamizole Magnesium or other pyrazolones, patients with existing severe bone‑marrow suppression, and those who have experienced agranulocytosis with prior use. Caution is also advised for patients with severe hepatic or renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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