Product image of Metamizol Stada (Metamizole Sodium Monohydrate) supplied by GNH India

Metamizol Stada

Active Ingredient:
Metamizole Sodium Monohydrate
Origin:
EU

Metamizol Stada (Metamizole Sodium Monohydrate)

Metamizole Sodium, the active ingredient in Metamizol Stada, is a pyrazolone analgesic presented as an oral tablet for oral use. It is used to relieve acute pain, reduce fever, and manage postoperative discomfort in adult patients.

GNH India supplies Metamizol Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Metamizol Stada, a pyrazolone analgesic, is employed in the management of pain and fever.
  • Acute pain: provides rapid analgesia for sudden severe pain.
  • Fever: lowers elevated body temperature in febrile states.
  • Post‑operative pain: controls discomfort after surgical procedures.
  • Colic: alleviates visceral pain associated with colic episodes.

How It Works

  • Metamizole Sodium acts by non‑selective inhibition of cyclooxygenase (COX‑1 and COX‑2) enzymes, reducing prostaglandin synthesis. The central analgesic effect is mediated through modulation of spinal pain pathways, while spasmolytic activity results from smooth‑muscle relaxation in the gastrointestinal and urinary tracts.

Side Effects

Metamizol Stada may cause a range of adverse reactions.

Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Sweating
  • Mild hypotension

Serious or Rare Side Effects

  • Agranulocytosis (severe drop in white blood cells)
  • Severe allergic reactions (anaphylaxis, skin rash)
  • Blood dyscrasias (thrombocytopenia, hemolytic anemia)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe liver injury
  • Renal impairment in susceptible individuals

Precautions & Warnings

  • Before prescribing Metamizol Stada, clinicians should consider several safety measures.
  • Assess renal function: evaluate kidney status in patients with existing impairment.
  • Monitor blood counts: perform regular hematologic monitoring for early detection of agranulocytosis.
  • Check for hypersensitivity: avoid use in individuals with known allergy to pyrazolones.
  • Avoid in severe hepatic disease: use only if benefits outweigh risks.
  • Adjust in elderly: start with the lowest effective dose and monitor closely.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metamizol Stada can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants: increased risk of bleeding.
  • Other NSAIDs: heightened gastrointestinal toxicity.
  • Allopurinol: elevated risk of agranulocytosis.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible reduction in blood‑pressure control.
  • Diuretics: increased potential for renal impairment.
  • Lithium: altered serum lithium levels, requiring monitoring.

Frequently Asked Questions

Metamizol Stada contains metamizole sodium, a pyrazolone analgesic that is used to treat acute pain, reduce fever, manage postoperative discomfort, and relieve colic‑related visceral pain in adult patients.

Metamizole sodium works by non‑selectively inhibiting cyclooxygenase enzymes, which lowers prostaglandin production. This results in central analgesic effects and spasmolytic activity that help alleviate pain and reduce fever.

The appropriate dose of Metamizol Stada is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and clinical response. Dosage instructions are provided on the prescription label.

Safety data for metamizole sodium in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Metamizol Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metamizol Stada belongs to the pyrazolone class, offering strong analgesic and antipyretic effects with a spasmolytic component. Compared with traditional NSAIDs, it may have a lower risk of gastrointestinal irritation but carries a rare risk of severe blood‑cell disorders, requiring regular monitoring.

Metamizol Stada should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat.

Metamizol Stada is administered orally. The tablet is swallowed whole with water, unless otherwise directed by a healthcare professional. It should be taken with or without food as advised by the prescriber.

The most serious risks include agranulocytosis, a potentially life‑threatening drop in white blood cells, and severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, or toxic epidermal necrolysis. Prompt medical attention is required if any signs of these conditions appear.

Metamizol Stada should be avoided in patients with known hypersensitivity to metamizole or other pyrazolones, those with severe liver or kidney impairment, and individuals with a history of blood‑cell disorders. It is also contraindicated in patients taking certain interacting medications without close monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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