Product image of Metamizol Teva (Metamizole Sodium Monohydrate) supplied by GNH India

Metamizol Teva

Active Ingredient:
Metamizole Sodium Monohydrate
Origin:
EU

Metamizol Teva (Metamizole Sodium Monohydrate)

Metamizole Sodium Monohydrate, the active ingredient in Metamizol Teva, is an analgesic, antipyretic presented as an oral formulation for oral use. It is employed to relieve moderate to severe pain and to reduce fever in adult patients.
GNH India supplies Metamizol Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Metamizol acts as a potent analgesic and antipyretic across several clinical situations.

  • Pain: provides effective relief of moderate to severe acute pain.
  • Fever: lowers elevated body temperature in febrile states.
  • Postoperative pain: helps control pain following surgical procedures.

How It Works

  • Metamizole’s exact mechanism is not fully defined; it is thought to inhibit cyclooxygenase enzymes, reducing prostaglandin synthesis, and to modulate endogenous opioid pathways, contributing to its analgesic and antipyretic actions without significant anti-inflammatory effects.

Side Effects

Metamizole may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Nausea: occasional upset stomach and vomiting.
  • Dizziness: transient light‑headedness or vertigo.
  • Headache: mild to moderate head pain.
  • Rash: skin redness or itching.
  • Hypotension: temporary drop in blood pressure.

Serious or Rare Side Effects

  • Agranulocytosis: severe reduction in white blood cells, potentially life‑threatening.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.
  • Anaphylaxis: rapid, severe allergic response requiring emergency care.
  • Hepatotoxicity: abnormal liver enzyme elevations.
  • Renal impairment: decreased kidney function in susceptible individuals.

Precautions & Warnings

Before prescribing Metamizol, clinicians should consider several safety measures.

  • Renal function assessment: evaluate kidney status, especially in elderly patients.
  • Hematologic monitoring: perform regular blood counts to detect early signs of agranulocytosis.
  • Hepatic caution: use carefully in patients with liver disease.
  • Hypersensitivity screening: avoid in individuals with known allergy to metamizole or related compounds.
  • Concomitant NSAIDs: limit use with other non‑steroidal anti‑inflammatory drugs to reduce additive toxicity.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Metamizol can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Other myelotoxic agents: combined use may increase risk of severe blood dyscrasias.
  • Concurrent NSAIDs: heightened potential for gastrointestinal bleeding and renal injury.
  • Anticoagulants: may amplify anticoagulant effect, raising bleeding risk.

Moderate Interactions (Monitor Closely)

  • Diuretics: concurrent therapy may affect renal clearance of Metamizol.
  • Alcohol: excessive intake can increase gastrointestinal irritation and dizziness.

Frequently Asked Questions

Metamizol Teva contains metamizole sodium monohydrate and is used as an analgesic and antipyretic. It provides relief from moderate to severe pain and helps lower high body temperature in febrile conditions, making it suitable for postoperative pain, acute injury pain, and fever management.

The exact mechanism of metamizole is not fully understood. It is believed to inhibit cyclooxygenase enzymes, reducing prostaglandin production, and to influence endogenous opioid pathways, which together contribute to its pain‑relieving and fever‑reducing effects.

The appropriate dose of Metamizol Teva is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and clinical response. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety data for metamizole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after evaluating individual circumstances.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metamizol offers strong analgesic and antipyretic effects similar to other non‑opioid pain relievers but differs by having a lower risk of gastrointestinal irritation. However, it carries a unique risk of agranulocytosis, which is less common with many NSAIDs, so safety monitoring is essential.

Metamizol Teva should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.

Metamizol Teva is administered orally. The tablet or liquid is taken with water, following the dosage prescribed by the healthcare professional. It should be swallowed whole unless the product label specifies otherwise.

The most serious adverse effect is agranulocytosis, a potentially life‑threatening drop in white blood cells. Other severe risks include Stevens‑Johnson syndrome, anaphylactic reactions, and significant liver or kidney impairment. Prompt medical attention is required if symptoms of these conditions appear.

Metamizol Teva should be avoided in individuals with known hypersensitivity to metamizole or any of its components, in patients with a history of agranulocytosis, and in those taking other myelotoxic drugs without close monitoring. Pregnant or breastfeeding women should use it only under strict medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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