Product image of Metamizol Vitória (Metamizole Magnesium) supplied by GNH India

Metamizol Vitória

Active Ingredient:
Metamizole Magnesium
Origin:
EU

Metamizol Vitória (Metamizole Magnesium)

Metamizole magnesium, the active ingredient in Metamizol Vitória, is a pyrazolone presented as an oral formulation for oral use. It is employed to relieve pain and reduce fever in adult patients.

GNH India supplies Metamizol Vitória as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Faes Farma Portugal, S.A.

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Indications & Clinical Uses

Metamizole magnesium is used as an analgesic and antipyretic within the pyrazolone class.

  • Pain: provides effective relief of moderate to severe acute pain.
  • Fever: lowers elevated body temperature associated with infectious or inflammatory conditions.
  • Post‑operative pain: helps control pain following surgical procedures.

How It Works

  • Metamizole magnesium exerts analgesic and antipyretic actions that are not fully elucidated. It is thought to inhibit prostaglandin synthesis centrally and may involve blockade of cyclooxygenase enzymes in the brain, reducing pain signaling and thermoregulatory responses.

Side Effects

Metamizole magnesium may cause a range of adverse reactions, most of which are dose‑related and reversible.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Vomiting: occasional episodes after dosing.
  • Dizziness: transient light‑headedness.
  • Rash: mild skin erythema.
  • Hypotension: temporary drop in blood pressure.
  • Headache: mild tension‑type headache.

Serious or Rare Side Effects

  • Agranulocytosis: severe reduction in white blood cells.
  • Anaphylaxis: acute allergic reaction with airway compromise.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane involvement.
  • Hepatotoxicity: liver enzyme elevation.
  • Hemolytic anemia: destruction of red blood cells.
  • Severe hypotension: persistent low blood pressure requiring medical intervention.

Precautions & Warnings

Before using Metamizole magnesium, consider the following safety measures.

  • Allergy assessment: avoid if known hypersensitivity to pyrazolones.
  • Blood monitoring: periodic complete blood count to detect agranulocytosis.
  • Renal function: evaluate kidney status in patients with impairment.
  • Hepatic function: assess liver enzymes in those with liver disease.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Metamizole magnesium can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants: increased bleeding risk.
  • Other pyrazolones: additive toxicity, especially agranulocytosis.
  • High‑dose aspirin: enhanced gastrointestinal irritation.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible enhancement of hypotensive effect.
  • Diuretics: may potentiate low blood pressure.
  • Lithium: potential for increased lithium levels.
  • Methotrexate: may raise methotrexate toxicity.

Frequently Asked Questions

Metamizol Vitória contains metamizole magnesium, a pyrazolone that is used as an analgesic to relieve moderate to severe pain and as an antipyretic to lower fever in adult patients. It is commonly prescribed for acute pain, postoperative discomfort, and febrile conditions.

The exact mechanism is not fully defined, but metamizole magnesium is believed to inhibit central prostaglandin synthesis and block cyclooxygenase activity in the brain. This reduces pain signaling pathways and resets the hypothalamic set‑point for body temperature, providing analgesic and antipyretic effects.

The appropriate dose of Metamizol Vitória is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, age, and renal or hepatic function. Healthcare professionals adjust the regimen to achieve effective pain relief or fever reduction while minimizing risk.

Safety data for metamizole magnesium in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after a thorough risk‑benefit assessment.

To order Metamizol Vitória, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metamizol Vitória belongs to the pyrazolone class, offering strong analgesic and antipyretic activity comparable to non‑steroidal anti‑inflammatory drugs (NSAIDs) but with a different safety profile. Unlike many NSAIDs, it has a lower risk of gastric irritation but carries a rare risk of agranulocytosis, which must be monitored.

Metamizol Vitória should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, and store it away from direct sunlight to maintain stability and potency.

Metamizol Vitória is formulated for oral administration. The tablets or oral solution are taken by mouth with or without food, as directed by the prescribing clinician. Swallow tablets whole; do not crush or chew unless specifically instructed.

The most serious adverse reactions include agranulocytosis, a potentially life‑threatening drop in white blood cells, and severe allergic responses such as anaphylaxis or Stevens‑Johnson syndrome. Prompt medical attention is required if signs of infection, rash, or breathing difficulty occur.

Metamizol Vitória should be avoided in individuals with known hypersensitivity to metamizole or other pyrazolones, patients with a history of agranulocytosis, and those with severe liver or kidney impairment unless a physician determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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