Product image of Metaperex (Alpha-Tocopherol) supplied by GNH India

Metaperex

Active Ingredient:
Alpha-Tocopherol
Origin:
EU

Metaperex (Alpha-Tocopherol)

Alpha-Tocopherol, the active ingredient in Metaperex, is a nutritional supplement presented as an unspecified oral formulation for adult use. It functions as a potent antioxidant, helping to protect cell membranes from oxidative damage and supporting overall nutritional health.

GNH India supplies Metaperex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑assured products that meet EU regulatory standards.

Manufacturer / TM Owner

Kora Corporation Limited

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Indications & Clinical Uses

Metaperex (alpha‑tocopherol) is used to address conditions related to oxidative stress and vitamin E deficiency.

  • Vitamin E deficiency: restores adequate levels of alpha‑tocopherol in individuals with documented deficiency.
  • Oxidative stress: provides antioxidant support to help protect cells from free‑radical damage.
  • Skin health: supports maintenance of healthy skin by reducing oxidative injury.

How It Works

  • Alpha‑tocopherol acts as a lipid‑soluble antioxidant that integrates into cellular membranes. It donates a hydrogen atom to neutralize lipid peroxyl radicals, thereby terminating chain reactions of lipid peroxidation. By stabilizing cell membranes and scavenging free radicals, it helps preserve membrane integrity and protects proteins and DNA from oxidative injury. The regenerated tocopheroxyl radical is then recycled by other antioxidants such as vitamin C, completing the antioxidant network.

Side Effects

Alpha‑tocopherol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Diarrhea: loose stools.
  • Headache: transient head discomfort.
  • Skin irritation: mild rash or itching at the site of contact.

Serious or Rare Side Effects

  • Allergic reaction: hives, swelling, or anaphylaxis.
  • Bleeding tendency: increased risk of hemorrhage, especially with anticoagulants.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.

Precautions & Warnings

When using Metaperex, consider the following precautions to ensure safe and effective use.

  • Pregnancy: consult a healthcare professional before use, as safety data are limited.
  • Breastfeeding: discuss with a physician, as the compound may be excreted in milk.
  • Anticoagulant therapy: monitor coagulation parameters due to potential enhanced bleeding.
  • High-dose use: avoid exceeding recommended amounts to prevent toxicity.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Alpha‑tocopherol may interact with certain medications, influencing their efficacy or safety.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect may raise bleeding risk.
  • Chemotherapy agents (e.g., cyclophosphamide): may reduce therapeutic efficacy.
  • Statins: potential for increased muscle toxicity.

Moderate Interactions (Monitor Closely)

  • Vitamin K antagonists other than warfarin: monitor clotting parameters.
  • High‑dose vitamin C: may affect antioxidant balance.
  • Lipid‑lowering agents (e.g., fibrates): observe for altered lipid profiles.

Frequently Asked Questions

Metaperex is an oral nutritional supplement that provides alpha‑tocopherol, a form of vitamin E. It is used to support antioxidant defenses, help manage vitamin E deficiency, and promote skin health by protecting cells from oxidative damage.

Alpha‑tocopherol is a lipid‑soluble antioxidant that integrates into cell membranes. It donates hydrogen atoms to neutralize free radicals, halting lipid peroxidation and preserving membrane integrity, while being regenerated by other antioxidants such as vitamin C.

The appropriate dose of Metaperex is determined by a qualified healthcare professional based on the individual’s nutritional needs, age, and clinical condition. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety data for high‑dose alpha‑tocopherol in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Metaperex to weigh potential benefits against any risks.

To order Metaperex, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metaperex delivers alpha‑tocopherol, the most biologically active form of vitamin E, in an oral dosage suitable for supplementation. Compared with mixed‑tocopherol preparations, it provides a higher proportion of the d‑alpha‑tocopherol isomer, which is generally considered more potent for antioxidant activity.

Metaperex should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. No refrigeration is required for this oral formulation.

Metaperex is taken orally, usually with food or a glass of water, as directed by a healthcare professional. The exact administration schedule (e.g., once daily or divided doses) is determined by the prescriber based on individual needs.

Serious risks, although rare, include allergic reactions such as hives, swelling or anaphylaxis, an increased tendency to bleed—especially in patients on anticoagulant therapy—and signs of liver dysfunction like jaundice or elevated liver enzymes. Any of these symptoms should prompt immediate medical attention.

Individuals with known hypersensitivity to alpha‑tocopherol or any excipients in the product should avoid Metaperex. Patients on high‑dose anticoagulants, those with bleeding disorders, or anyone advised against vitamin E supplementation by their physician should also refrain from using it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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