Product image of Metformin Auxilto (Metformin Hydrochloride) supplied by GNH India

Metformin Auxilto

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Metformin Auxilto (Metformin Hydrochloride)

Metformin, the active ingredient in Metformin Auxilto, is a Biguanide presented as an oral tablet for oral use. It lowers blood glucose levels and is primarily prescribed for adults with type 2 diabetes mellitus, helping improve glycaemic control when used alongside diet and exercise. Metformin works by reducing hepatic glucose production and increasing peripheral insulin sensitivity, which together contribute to better metabolic balance.

GNH India supplies Metformin Auxilto as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Auxilto Healthcare S.R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Metformin is indicated for conditions related to impaired glucose regulation and type 2 diabetes management.
  • Type 2 diabetes mellitus: improves glycaemic control by lowering fasting and post‑prandial blood glucose levels.
  • Prediabetes (impaired fasting glucose): delays progression to type 2 diabetes when combined with lifestyle modification.
  • Polycystic ovary syndrome (PCOS): helps reduce insulin resistance and may improve menstrual regularity.

How It Works

  • Metformin primarily inhibits mitochondrial respiratory‑chain complex I, leading to reduced hepatic gluconeogenesis. The resulting decrease in hepatic glucose output, together with enhanced peripheral glucose uptake in muscle and adipose tissue via activation of AMP‑activated protein kinase (AMPK), improves insulin sensitivity and lowers circulating blood glucose concentrations. It does not stimulate insulin secretion, which minimizes the risk of hypoglycaemia when used alone.

Side Effects

Metformin may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Nausea or abdominal discomfort
  • Diarrhea
  • Metallic taste in the mouth

Serious or Rare Side Effects

  • Lactic acidosis (potentially fatal)
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatic failure

Precautions & Warnings

  • Metformin requires careful monitoring and patient education before and during therapy.
  • Renal function: assess creatinine clearance before initiating therapy and periodically thereafter.
  • Hepatic function: avoid use in patients with significant liver disease.
  • Alcohol consumption: limit intake to reduce risk of lactic acidosis.
  • Elderly patients: start at lower dose and monitor for intolerance.
  • Vitamin B12 levels: monitor periodically as long‑term use may cause deficiency.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Metformin can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Iodinated contrast agents: may precipitate lactic acidosis; discontinue metformin before and after imaging.
  • Cimetidine: can increase metformin plasma concentrations.
  • Alcohol: potentiates risk of lactic acidosis.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask hypoglycaemia symptoms.
  • Diuretics (especially thiazides): can affect renal clearance of metformin.
  • ACE inhibitors/ARBs: monitor renal function when combined.

Frequently Asked Questions

Metformin Auxilto is used to improve blood glucose control in adults with type 2 diabetes mellitus. It may also be prescribed for prediabetes to help delay progression to diabetes and, in some regions, for polycystic ovary syndrome to address insulin resistance.

Metformin reduces hepatic glucose production and enhances peripheral glucose uptake by activating AMP‑activated protein kinase (AMPK). This dual action lowers circulating blood glucose without stimulating insulin secretion, thereby improving overall insulin sensitivity.

The dose of Metformin Auxilto is individualized by the prescribing healthcare professional based on factors such as the patient’s renal function, glycaemic targets, concomitant medications, and tolerance. No fixed regimen is provided here.

Data on Metformin use during pregnancy are limited, and it is generally prescribed only when the potential benefits outweigh the risks. Breastfeeding mothers should consult their physician, as Metformin does pass into breast milk in small amounts.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metformin is a first‑line Biguanide that lowers glucose without causing weight gain and has a low risk of hypoglycaemia when used alone. Compared with sulfonylureas, it does not stimulate insulin release, and unlike insulin therapy, it is administered orally.

Store Metformin Auxilto at room temperature, ideally below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct heat, and discard any product that appears discoloured or damaged.

Metformin Auxilto is taken orally, usually with meals to reduce gastrointestinal discomfort. Tablets should be swallowed whole with a full glass of water; crushing or chewing is not recommended unless specifically instructed by a healthcare professional.

The most serious risk is lactic acidosis, a rare but potentially fatal condition that may present with muscle pain, rapid breathing, abdominal discomfort, or feeling unusually weak. Severe skin reactions such as Stevens‑Johnson syndrome and hepatic failure are also rare but critical concerns.

Metformin should be avoided in patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²), acute or chronic metabolic acidosis, known hypersensitivity to metformin, or those receiving iodinated contrast studies without appropriate discontinuation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.