Product image of Metformin Nevik (Metformin Hydrochloride) supplied by GNH India

Metformin Nevik

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Metformin Nevik (Metformin Hydrochloride)

Metformin Hydrochloride, the active ingredient in Metformin Nevik, is a biguanide presented as an oral dosage form for oral use. It is employed to improve glycemic control in adults with type 2 diabetes mellitus. By decreasing hepatic glucose output and enhancing peripheral insulin sensitivity, it helps lower blood glucose levels as part of a comprehensive diabetes management plan.

GNH India supplies Metformin Nevik as a licensed, GDP‑compliant international pharmaceutical product serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Nevik Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metformin Nevik is a biguanide that acts on glucose metabolism to manage hyperglycaemia.

  • Type 2 diabetes mellitus: improves glycaemic control by lowering fasting and post‑prandial blood glucose levels.
  • Prediabetes (impaired glucose tolerance): delays progression to overt diabetes when combined with lifestyle measures.
  • Gestational diabetes mellitus: may be used when diet alone does not achieve target glucose levels, under specialist supervision.

How It Works

  • Metformin Hydrochloride reduces hepatic gluconeogenesis and increases peripheral glucose uptake by activating AMP‑activated protein kinase (AMPK). This leads to decreased liver glucose production, enhanced insulin‑mediated glucose utilization in muscle, and modest improvements in lipid metabolism, collectively contributing to lower plasma glucose concentrations.

Side Effects

Metformin Nevik may be associated with a range of adverse reactions.

Common Side Effects

  • Gastrointestinal upset: nausea, abdominal discomfort, or diarrhoea.
  • Metallic taste in the mouth.
  • Decreased appetite.
  • Mild headache.
  • Weight loss or reduced body mass index.

Serious or Rare Side Effects

  • Lactic acidosis: a rare but potentially fatal metabolic disturbance.
  • Severe hypoglycaemia (usually when combined with other glucose‑lowering agents).
  • Hepatotoxicity: elevated liver enzymes.
  • Skin reactions: rash or pruritus.
  • Vitamin B12 deficiency with long‑term use.

Precautions & Warnings

Metformin Nevik requires careful use in several clinical situations.

  • Renal function assessment: avoid or adjust dose in patients with impaired renal clearance.
  • Hepatic disease: monitor liver function before and during therapy.
  • Cardiovascular status: use cautiously in patients with unstable heart failure.
  • Alcohol consumption: limit intake to reduce risk of lactic acidosis.
  • Pregnancy and lactation: evaluate risk‑benefit ratio with a healthcare professional.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Metformin Nevik can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Iodinated contrast agents: may precipitate acute renal failure, increasing lactic acidosis risk.
  • Cimetidine: can raise metformin plasma concentrations.
  • Certain antiretrovirals (e.g., didanosine): increase risk of lactic acidosis.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask hypoglycaemia symptoms.
  • Diuretics (loop or thiazide): can affect renal function and metformin clearance.
  • ACE inhibitors or ARBs: monitor renal function and electrolytes.
  • Oral corticosteroids: may raise blood glucose, requiring dose adjustment.
  • Thyroid hormones: may influence glucose metabolism, necessitating monitoring.

Frequently Asked Questions

Metformin Nevik contains metformin hydrochloride, an oral antidiabetic medication used primarily to improve blood‑sugar control in adults with type 2 diabetes mellitus and, in some clinical settings, for prediabetes or gestational diabetes under specialist guidance.

Metformin activates AMP‑activated protein kinase (AMPK), which suppresses hepatic glucose production and enhances insulin‑mediated glucose uptake in muscle and fat tissues, thereby lowering circulating glucose levels without directly stimulating insulin secretion.

The appropriate dose of Metformin Nevik is determined by the prescribing healthcare professional based on the individual’s renal function, glycaemic targets, and tolerance. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of metformin during pregnancy or lactation should be evaluated by a qualified clinician. While some guidelines allow its use when benefits outweigh risks, the decision must be individualized and discussed with a healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metformin is a first‑line biguanide that improves insulin sensitivity without causing hypoglycaemia when used alone, unlike sulfonylureas or insulin. It is generally well‑tolerated, inexpensive, and has a favourable impact on weight, making it a preferred initial therapy for many patients with type 2 diabetes.

Metformin Nevik should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Metformin Nevik is taken orally, usually with meals to minimise gastrointestinal discomfort. The tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed by a healthcare professional.

The most serious potential risk is lactic acidosis, a rare but life‑threatening condition that can occur in patients with severe renal impairment, hepatic disease, or excessive alcohol intake. Prompt medical attention is required if symptoms such as rapid breathing, muscle pain, or abdominal discomfort develop.

Metformin Nevik is contraindicated in patients with known hypersensitivity to metformin, severe renal impairment (eGFR < 30 mL/min/1.73 m²), acute or chronic metabolic acidosis, including diabetic ketoacidosis, and in those with conditions that predispose to hypoxia or lactic acidosis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Metformin Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT