Product image of Metformin Teva (Metformin) supplied by GNH India

Metformin Teva

Active Ingredient:
Metformin
Origin:
EU

Metformin Teva (Metformin)

Metformin, the active ingredient in Metformin Teva, is a biguanide presented as a tablet for oral use. It reduces hepatic glucose production and improves peripheral insulin sensitivity, helping to control elevated blood glucose levels in adults diagnosed with type 2 diabetes mellitus as part of a broader therapeutic regimen.

GNH India supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing EU‑sourced product that meets stringent quality standards for global distribution.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Metformin Teva is indicated for conditions related to abnormal glucose metabolism.

  • Type 2 diabetes mellitus: improves glycemic control by lowering fasting and post‑prandial blood glucose.
  • Impaired glucose tolerance: delays progression to overt diabetes when combined with lifestyle measures.
  • Polycystic ovary syndrome: reduces insulin resistance and may improve menstrual regularity.

How It Works

  • Metformin acts primarily by inhibiting mitochondrial respiratory-chain complex I, which decreases hepatic gluconeogenesis. It also enhances peripheral glucose uptake by increasing insulin‑mediated activation of AMP‑activated protein kinase (AMPK), leading to reduced intestinal glucose absorption and improved insulin sensitivity in muscle and adipose tissue.

Side Effects

Metformin may cause a range of adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, abdominal discomfort, or diarrhea.
  • Metallic taste: transient alteration in taste perception.
  • Vitamin B12 deficiency: reduced absorption with long‑term use.

Serious or Rare Side Effects

  • Lactic acidosis: rare but life‑threatening metabolic disturbance.
  • Severe hypoglycemia: usually when combined with other glucose‑lowering agents.
  • Hepatotoxicity: uncommon liver enzyme elevation.

Precautions & Warnings

When prescribing Metformin Teva, clinicians should consider several safety precautions to minimize risk.

  • Renal function: assess creatinine clearance before initiation and periodically thereafter.
  • Lactic acidosis risk: avoid in patients with severe renal or hepatic impairment.
  • Alcohol consumption: limit intake as it may increase acidosis risk.
  • Pregnancy and lactation: evaluate benefits versus risks with obstetric guidance.
  • Drug interactions: review concomitant medications that affect renal clearance.
  • Store at ambient temperature: keep below 25 °C in the original container, protected from moisture.

Avoid Interactions

Metformin Teva can interact with other medicines, influencing its plasma concentration or safety profile.

Major Interactions (Avoid)

  • Iodinated contrast agents: may precipitate renal dysfunction and increase lactic acidosis risk.
  • Cimetidine: can raise metformin plasma levels, enhancing toxicity.
  • Chronic alcohol abuse: heightens risk of lactic acidosis.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask hypoglycemia symptoms.
  • Diuretics (thiazides): can affect renal clearance and electrolyte balance.
  • ACE inhibitors or ARBs: require monitoring of renal function and lactic acidosis signs.

Frequently Asked Questions

Metformin Teva is used to improve blood glucose control in adults with type 2 diabetes mellitus. It works as part of a comprehensive treatment plan that may include diet, exercise, and other medications to achieve target glycemic levels.

Metformin lowers blood sugar by decreasing the liver’s production of glucose, reducing intestinal absorption of glucose, and enhancing the sensitivity of muscle and fat cells to insulin, thereby facilitating more efficient glucose utilization.

The appropriate dose of Metformin Teva is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and renal function. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of Metformin Teva during pregnancy or lactation should be evaluated by a qualified healthcare provider. The prescriber will weigh potential benefits against possible risks and decide whether continuation is appropriate for the mother and child.

To order Metformin Teva, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metformin belongs to the biguanide class and is often first‑line therapy for type 2 diabetes because of its efficacy, low risk of hypoglycemia, and weight‑neutral profile. Compared with sulfonylureas or insulin, it does not typically cause weight gain and has a well‑established safety record.

Metformin Teva should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture and keep them out of reach of children to maintain product integrity.

Metformin Teva is taken orally, usually with meals to reduce gastrointestinal discomfort. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed by a healthcare professional.

The most serious risk is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal or hepatic impairment, excessive alcohol intake, or other predisposing factors. Prompt medical attention is required if symptoms such as rapid breathing, muscle pain, or abdominal discomfort develop.

Metformin Teva is contraindicated in individuals with severe renal impairment, acute or chronic metabolic acidosis, known hypersensitivity to metformin, or those receiving radiographic contrast studies that may affect kidney function. Patients with these conditions should discuss alternative therapies with their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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