Metformin Teva

Active Ingredient:: Metformin Hydrochloride
Origin:: EU

Metformin Teva (Metformin Hydrochloride)

Q: What is Metformin Teva used for?

Metformin Teva is used to improve blood‑sugar control in adults with type 2 diabetes mellitus. It may also be prescribed for prediabetes to help delay progression to diabetes and, off‑label, for insulin‑resistant conditions such as polycystic ovary syndrome.

Q: How does Metformin Hydrochloride work?

Metformin Hydrochloride reduces hepatic glucose production, increases peripheral insulin sensitivity, and modestly decreases intestinal glucose absorption. These actions lower circulating glucose levels without directly stimulating insulin secretion.

Q: What is the usual dose of Metformin Teva?

The dose of Metformin Teva is individualized by the prescribing clinician based on the patient’s renal function, glycaemic targets, and tolerability. Dosage adjustments are made according to clinical response and safety considerations.

Q: Is Metformin Teva safe during pregnancy or breastfeeding?

Metformin is classified as pregnancy category B in many regions, indicating no proven risk in animal studies but limited human data. It may be continued during pregnancy if benefits outweigh risks, and it is excreted in breast milk in small amounts; clinicians should evaluate each case.

Q: How do I order Metformin Teva from GNH India?

To order, submit an enquiry on the Metformin Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Q: How does Metformin compare with other antidiabetic drug classes?

Metformin belongs to the biguanide class and is typically first‑line therapy for type 2 diabetes because it does not cause weight gain and has a low risk of hypoglycaemia. Compared with sulfonylureas, it has a more favourable safety profile, and unlike insulin, it is administered orally.

Q: How should Metformin Teva be stored?

Store Metformin Teva at ambient temperature, below 25 °C, in the original packaging. Keep the product away from moisture, heat, and direct sunlight to maintain stability.

Q: How is Metformin Teva administered?

Metformin Teva is taken orally, usually with meals to minimise gastrointestinal upset. Tablets should be swallowed whole with a glass of water; they are not intended for crushing or chewing unless specifically instructed by a healthcare professional.

Q: What are the most serious risks to watch for with Metformin Teva?

The most serious risk is lactic acidosis, a rare but potentially fatal condition characterised by rapid breathing, muscle pain, and abdominal discomfort. Other serious concerns include severe hypoglycaemia (when combined with insulin or sulfonylureas) and marked vitamin B12 deficiency with long‑term use.

Q: Who should not use Metformin Teva?

Metformin Teva should be avoided in patients with severe renal impairment (eGFR <30 mL/min/1.73 m²), acute or chronic metabolic acidosis, significant hepatic disease, or a history of lactic acidosis. Caution is also advised for individuals with unstable heart failure.

Metformin Hydrochloride, the active ingredient in Metformin Teva, is a biguanide presented as a tablet for oral use. It lowers blood glucose levels in adults with type 2 diabetes mellitus by decreasing hepatic glucose output and improving peripheral insulin sensitivity, thereby supporting better glycemic control.

GNH India supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharmaceuticals Cr, S.R.O.

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Indications & Clinical Uses

Metformin Teva is an oral antidiabetic agent indicated for conditions that affect glucose metabolism.
Type 2 diabetes mellitus: improves glycaemic control and reduces HbA1c levels.
Prediabetes (impaired glucose tolerance): helps delay progression to overt diabetes.
Polycystic ovary syndrome (off‑label): reduces insulin resistance and may improve menstrual regularity.

How It Works

Metformin Hydrochloride primarily inhibits hepatic gluconeogenesis, reducing the amount of glucose released into the bloodstream. It also enhances peripheral glucose uptake by increasing insulin‑stimulated translocation of GLUT‑4 transporters in muscle and adipose tissue, and modestly decreases intestinal glucose absorption, collectively improving overall insulin sensitivity.

Side Effects

Metformin Teva may cause a range of adverse reactions.

Common Side Effects

Nausea: mild to moderate stomach upset.
Diarrhoea: frequent loose stools, especially at treatment initiation.
Abdominal discomfort: cramping or bloating.
Metallic taste: transient alteration in taste perception.
Loss of appetite: reduced desire to eat.
Vitamin B12 deficiency: gradual decrease with long‑term use.

Serious or Rare Side Effects

Lactic acidosis: rare but life‑threatening metabolic acidosis.
Severe hypoglycaemia: uncommon when used alone.
Hepatic dysfunction: elevated liver enzymes.
Skin rash or hypersensitivity: including Stevens‑Johnson syndrome.
Anemia: due to folate or B12 deficiency.
Acute pancreatitis: very rare inflammatory condition.

Precautions & Warnings

Metformin Teva requires careful consideration of several clinical factors before and during therapy.
Renal function: assess eGFR and avoid use if eGFR <30 mL/min/1.73 m².
Liver disease: contraindicated in severe hepatic impairment.
Cardiac failure: use with caution in unstable heart failure.
Alcohol consumption: limit intake to reduce lactic acidosis risk.
Vitamin B12 monitoring: periodic assessment recommended for long‑term therapy.
Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Metformin Teva can interact with other medicines, affecting safety or effectiveness.

Major Interactions (Avoid)

Iodinated contrast agents: may precipitate acute renal failure.
Cimetidine: can increase metformin plasma concentrations.
Nucleoside reverse transcriptase inhibitors: raise risk of lactic acidosis.

Moderate Interactions (Monitor Closely)

Beta‑blockers: may mask symptoms of hypoglycaemia.
Diuretics: can affect renal clearance of metformin.
ACE inhibitors/ARBs: monitor renal function and electrolytes.
Alcohol: potentiates lactic acidosis risk.
Calcium channel blockers: may modestly increase metformin levels.

Frequently Asked Questions

Metformin Teva is used to improve blood‑sugar control in adults with type 2 diabetes mellitus. It may also be prescribed for prediabetes to help delay progression to diabetes and, off‑label, for insulin‑resistant conditions such as polycystic ovary syndrome.

Metformin Hydrochloride reduces hepatic glucose production, increases peripheral insulin sensitivity, and modestly decreases intestinal glucose absorption. These actions lower circulating glucose levels without directly stimulating insulin secretion.

The dose of Metformin Teva is individualized by the prescribing clinician based on the patient’s renal function, glycaemic targets, and tolerability. Dosage adjustments are made according to clinical response and safety considerations.

Metformin is classified as pregnancy category B in many regions, indicating no proven risk in animal studies but limited human data. It may be continued during pregnancy if benefits outweigh risks, and it is excreted in breast milk in small amounts; clinicians should evaluate each case.

To order, submit an enquiry on the Metformin Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metformin belongs to the biguanide class and is typically first‑line therapy for type 2 diabetes because it does not cause weight gain and has a low risk of hypoglycaemia. Compared with sulfonylureas, it has a more favourable safety profile, and unlike insulin, it is administered orally.

Store Metformin Teva at ambient temperature, below 25 °C, in the original packaging. Keep the product away from moisture, heat, and direct sunlight to maintain stability.

Metformin Teva is taken orally, usually with meals to minimise gastrointestinal upset. Tablets should be swallowed whole with a glass of water; they are not intended for crushing or chewing unless specifically instructed by a healthcare professional.

The most serious risk is lactic acidosis, a rare but potentially fatal condition characterised by rapid breathing, muscle pain, and abdominal discomfort. Other serious concerns include severe hypoglycaemia (when combined with insulin or sulfonylureas) and marked vitamin B12 deficiency with long‑term use.

Metformin Teva should be avoided in patients with severe renal impairment (eGFR <30 mL/min/1.73 m²), acute or chronic metabolic acidosis, significant hepatic disease, or a history of lactic acidosis. Caution is also advised for individuals with unstable heart failure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 06 Sep 2026

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