Product image of Metformin Teva (Metformin Hydrochloride) supplied by GNH India

Metformin Teva

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Metformin Teva (Metformin Hydrochloride)

Metformin Hydrochloride, the active ingredient in Metformin Teva, is a biguanide presented as an oral tablet for oral use. It is used to lower blood glucose levels in adults with type 2 diabetes mellitus. The medication works by reducing hepatic glucose production and improving peripheral insulin sensitivity, helping to achieve better glycaemic control.

GNH India supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures product quality through rigorous testing and adherence to global regulatory standards.

Manufacturer / TM Owner

Teva Pharma B.V.

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Indications & Clinical Uses

Metformin Teva, a biguanide antidiabetic, is employed in the management of glucose metabolism disorders.

  • Type 2 diabetes mellitus: improves glycaemic control by lowering fasting and post‑prandial glucose levels.
  • Prediabetes (impaired fasting glucose): reduces the risk of progression to overt diabetes when combined with lifestyle measures.
  • Polycystic ovary syndrome: may improve insulin resistance and assist in menstrual regularity.

How It Works

  • Metformin Hydrochloride acts primarily by inhibiting hepatic gluconeogenesis, thereby decreasing the amount of glucose released into the bloodstream. It also enhances peripheral glucose uptake and utilization by increasing insulin sensitivity in muscle and adipose tissue, without directly stimulating insulin secretion. These actions collectively lower fasting plasma glucose and improve overall glycaemic control in patients with type 2 diabetes.

Side Effects

Metformin Teva may be associated with a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Diarrhea
  • Metallic taste

Serious or Rare Side Effects

  • Lactic acidosis (potentially fatal)
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatic dysfunction

Precautions & Warnings

When prescribing Metformin Teva, clinicians should consider several safety measures.

  • Renal function: assess creatinine clearance before initiating therapy.
  • Hepatic function: monitor liver enzymes in patients with liver disease.
  • Age: start with a lower dose in elderly patients.
  • Concomitant medications: review for drugs that may increase risk of lactic acidosis.
  • Contraindications: avoid in patients with known hypersensitivity to metformin.
  • Store at room temperature: keep in original container, protect from moisture.

Avoid Interactions

Metformin Teva can interact with other medicines, requiring careful assessment.

Major Interactions (Avoid)

  • Iodinated contrast agents (risk of renal impairment).
  • Cimetidine (increases metformin plasma levels).
  • Alcohol abuse (enhances risk of lactic acidosis).

Moderate Interactions (Monitor Closely)

  • Beta‑blockers (may mask hypoglycaemia symptoms).
  • Diuretics (affect renal clearance).
  • NSAIDs (reduce renal perfusion).

Frequently Asked Questions

Metformin Teva is a generic formulation of metformin hydrochloride indicated for the treatment of type 2 diabetes mellitus. It helps lower elevated blood glucose by decreasing hepatic glucose production and improving the body's response to insulin, thereby supporting better long‑term glycaemic control.

Metformin Hydrochloride works mainly by inhibiting the liver's production of glucose (gluconeogenesis) and by increasing the sensitivity of muscle and fat cells to insulin. This dual action reduces the amount of glucose released into the bloodstream and enhances peripheral glucose uptake, leading to lower blood sugar levels.

The appropriate dose of Metformin Teva is determined by the prescribing healthcare professional based on the individual’s clinical condition, renal function, and response to therapy. Dosage adjustments are made according to therapeutic goals and tolerability, and patients should follow the prescriber’s specific instructions.

Metformin may be used during pregnancy when the potential benefits outweigh any risks, often in women with gestational diabetes or pre‑existing type 2 diabetes. However, safety data are limited, and the decision should be made by a qualified clinician. Metformin is excreted in breast milk, so breastfeeding mothers should consult their doctor before use.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Metformin belongs to the biguanide class and is often first‑line therapy for type 2 diabetes because of its efficacy, low risk of hypoglycaemia, and favourable impact on weight. Compared with sulfonylureas or insulin, metformin does not stimulate insulin secretion, which reduces the chance of low blood sugar episodes and is generally well tolerated.

Metformin Teva should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.

Metformin Teva is taken orally, usually with meals to minimise gastrointestinal discomfort. The tablets are swallowed whole with a full glass of water. Patients should follow the dosing schedule prescribed by their healthcare provider and not crush or chew the tablets unless specifically instructed.

The most serious potential risk is lactic acidosis, a rare but life‑threatening condition that can occur in patients with severe renal impairment, hepatic disease, or excessive alcohol intake. Other serious concerns include severe skin reactions such as Stevens‑Johnson syndrome and significant hepatic dysfunction. Prompt medical attention is required if any of these symptoms arise.

Metformin Teva is contraindicated in individuals with known hypersensitivity to metformin, severe renal impairment (eGFR < 30 mL/min/1.73 m²), acute or chronic metabolic acidosis, and in patients receiving iodinated contrast studies without appropriate renal monitoring. Clinicians should also exercise caution in patients with liver disease, heart failure, or a history of alcohol abuse.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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