Metformin Teva

Active Ingredient:: Metformin Hydrochloride
Origin:: EU

Metformin Teva (Metformin Hydrochloride)

Q: What is Metformin Teva used for?

Metformin Teva is an oral biguanide indicated for the management of type 2 diabetes mellitus. It helps lower elevated blood glucose by improving insulin sensitivity and reducing hepatic glucose production. In some regions it is also prescribed off‑label for polycystic ovary syndrome to address insulin resistance.

Q: How does Metformin work in the body?

Metformin activates AMP‑activated protein kinase (AMPK) in liver and muscle cells. This activation suppresses gluconeogenesis in the liver and enhances peripheral glucose uptake, leading to reduced blood glucose levels. The drug does not stimulate insulin secretion, which differentiates it from many other antidiabetic agents.

Q: What is the usual dose of Metformin Teva?

The specific dose of Metformin Teva is determined by the prescribing clinician based on the patient’s glycemic targets, renal function, and tolerability. Dosage may be adjusted gradually to minimize gastrointestinal side effects, and the prescriber will provide individualized instructions.

Q: Is Metformin safe during pregnancy or breastfeeding?

Metformin is classified as pregnancy category B in many jurisdictions, indicating no proven risk in animal studies, but human data are limited. It may be continued during pregnancy if the benefits outweigh potential risks, especially in women with pre‑existing diabetes. Metformin does pass into breast milk in small amounts; clinicians should evaluate safety on a case‑by‑case basis.

Q: How do I order Metformin Teva from GNH India?

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. After verification, the sales team will provide pricing, availability, shipping details (including any temperature requirements), and assist with import documentation.

Q: How does Metformin compare with other antidiabetic drugs?

Metformin is often first‑line therapy for type 2 diabetes because it improves insulin sensitivity without causing weight gain and has a low risk of hypoglycemia when used alone. Compared with sulfonylureas, it does not stimulate insulin release, and unlike insulin therapy, it is administered orally. Its cardiovascular safety profile is favorable relative to many newer agents.

Q: What are the recommended storage conditions for Metformin Teva?

Metformin Teva tablets should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, heat, and direct sunlight. Do not store in the bathroom or near a kitchen sink where humidity is high.

Q: How is Metformin Teva administered?

Metformin Teva is taken orally, usually with meals to reduce gastrointestinal discomfort. Tablets should be swallowed whole with a full glass of water. The exact timing (e.g., with breakfast and dinner) is directed by the prescribing clinician based on the individual treatment plan.

Q: What are the most serious risks associated with Metformin?

The most serious adverse reaction is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal or hepatic impairment, dehydration, or excessive alcohol intake. Prompt medical attention is required if symptoms such as unexplained fatigue, rapid breathing, or abdominal pain develop.

Q: Who should not use Metformin Teva?

Metformin is contraindicated in patients with severe renal impairment (eGFR <30 mL/min/1.73 m²), acute or chronic metabolic acidosis, including diabetic ketoacidosis, and in those with known hypersensitivity to metformin or any component of the formulation. Caution is also advised for individuals with significant liver disease or a history of lactic acidosis.

Metformin, the active ingredient in Metformin Teva, is a biguanide presented as a tablet for oral use. It treats type 2 diabetes mellitus and is sometimes used off‑label for polycystic ovary syndrome in adults.

GNH India supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Sweden Ab

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Indications & Clinical Uses

Metformin is indicated for conditions that involve impaired glucose regulation or insulin resistance.
Type 2 diabetes mellitus: improves glycemic control by lowering fasting and post‑prandial blood glucose levels.
Polycystic ovary syndrome (off‑label): may improve insulin resistance and help restore regular menstrual cycles.

How It Works

Metformin reduces hepatic gluconeogenesis and enhances peripheral glucose uptake by activating AMP‑activated protein kinase (AMPK). This leads to decreased hepatic glucose output and increased insulin sensitivity in muscle and adipose tissue, resulting in lower circulating blood glucose concentrations without directly stimulating insulin secretion.

Side Effects

Metformin is generally well tolerated, but a range of adverse reactions have been reported.

Common Side Effects

Nausea
Diarrhea
Abdominal discomfort
Metallic taste
Loss of appetite
Flatulence

Serious or Rare Side Effects

Lactic acidosis
Severe skin reactions (e.g., Stevens‑Johnson syndrome)
Hepatic dysfunction
Hypoglycemia when combined with other glucose‑lowering agents
Vitamin B12 deficiency with long‑term use
Acute pancreatitis

Precautions & Warnings

Metformin should be used with attention to several safety considerations.
Renal function assessment: avoid use in severe renal impairment (eGFR <30 mL/min/1.73 m²).
Hepatic disease monitoring: use cautiously in patients with liver dysfunction.
Risk of lactic acidosis: discontinue before radiologic contrast studies or major surgery.
Alcohol consumption: limit intake to reduce lactic acidosis risk.
Vitamin B12 monitoring: periodic testing recommended for long‑term therapy.
Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Metformin may interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

Iodinated contrast agents: increase risk of lactic acidosis.
Cimetidine: can raise metformin plasma concentrations.
Alcohol: potentiates lactic acidosis.
Loop diuretics causing dehydration: raise risk of renal impairment.
Certain antiretrovirals (e.g., didanosine): increase toxicity.

Moderate Interactions (Monitor Closely)

Beta‑blockers: may mask hypoglycemia symptoms.
ACE inhibitors or ARBs: monitor renal function and potassium.
Thiazide diuretics: may affect glucose control.
Warfarin: monitor INR as metformin can alter anticoagulant effect.
Oral contraceptives: may slightly increase plasma metformin levels.
Statins: monitor for rare myopathy when combined.

Frequently Asked Questions

Metformin Teva is an oral biguanide indicated for the management of type 2 diabetes mellitus. It helps lower elevated blood glucose by improving insulin sensitivity and reducing hepatic glucose production. In some regions it is also prescribed off‑label for polycystic ovary syndrome to address insulin resistance.

Metformin activates AMP‑activated protein kinase (AMPK) in liver and muscle cells. This activation suppresses gluconeogenesis in the liver and enhances peripheral glucose uptake, leading to reduced blood glucose levels. The drug does not stimulate insulin secretion, which differentiates it from many other antidiabetic agents.

The specific dose of Metformin Teva is determined by the prescribing clinician based on the patient’s glycemic targets, renal function, and tolerability. Dosage may be adjusted gradually to minimize gastrointestinal side effects, and the prescriber will provide individualized instructions.

Metformin is classified as pregnancy category B in many jurisdictions, indicating no proven risk in animal studies, but human data are limited. It may be continued during pregnancy if the benefits outweigh potential risks, especially in women with pre‑existing diabetes. Metformin does pass into breast milk in small amounts; clinicians should evaluate safety on a case‑by‑case basis.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. After verification, the sales team will provide pricing, availability, shipping details (including any temperature requirements), and assist with import documentation.

Metformin is often first‑line therapy for type 2 diabetes because it improves insulin sensitivity without causing weight gain and has a low risk of hypoglycemia when used alone. Compared with sulfonylureas, it does not stimulate insulin release, and unlike insulin therapy, it is administered orally. Its cardiovascular safety profile is favorable relative to many newer agents.

Metformin Teva tablets should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, heat, and direct sunlight. Do not store in the bathroom or near a kitchen sink where humidity is high.

Metformin Teva is taken orally, usually with meals to reduce gastrointestinal discomfort. Tablets should be swallowed whole with a full glass of water. The exact timing (e.g., with breakfast and dinner) is directed by the prescribing clinician based on the individual treatment plan.

The most serious adverse reaction is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal or hepatic impairment, dehydration, or excessive alcohol intake. Prompt medical attention is required if symptoms such as unexplained fatigue, rapid breathing, or abdominal pain develop.

Metformin is contraindicated in patients with severe renal impairment (eGFR <30 mL/min/1.73 m²), acute or chronic metabolic acidosis, including diabetic ketoacidosis, and in those with known hypersensitivity to metformin or any component of the formulation. Caution is also advised for individuals with significant liver disease or a history of lactic acidosis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 06 Sep 2026

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