Product image of Metformin Vitabalans (Metformin Hydrochloride) supplied by GNH India

Metformin Vitabalans

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Metformin Vitabalans (Metformin Hydrochloride)

Metformin Hydrochloride, the active ingredient in Metformin Vitabalans, is a biguanide presented as an oral tablet for oral use. It treats type 2 diabetes mellitus in adults by improving blood‑glucose control.
GNH India supplies Metformin Vitabalans as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vitabalans Oy

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Indications & Clinical Uses

Metformin Vitabalans is a biguanide indicated for conditions where glucose regulation is impaired.

  • Type 2 diabetes mellitus: lowers fasting and post‑prandial blood glucose levels.
  • Prediabetes (impaired glucose tolerance): reduces the risk of progression to overt diabetes.
  • Polycystic ovary syndrome (off‑label): helps improve insulin resistance and menstrual regularity.

How It Works

  • Metformin Hydrochloride reduces hepatic gluconeogenesis, decreases intestinal glucose absorption, and enhances peripheral insulin sensitivity by activating AMP‑activated protein kinase (AMPK). These actions collectively lower circulating glucose without stimulating insulin secretion, providing glycaemic control in insulin‑resistant states.

Side Effects

Metformin Vitabalans may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, especially during treatment initiation.
  • Abdominal discomfort: cramping or bloating.
  • Metallic taste: transient after dosing.
  • Weight loss: modest reduction in body weight.
  • Vitamin B12 deficiency: decreased absorption over long‑term use.

Serious or Rare Side Effects

  • Lactic acidosis: rare but potentially fatal metabolic acidosis.
  • Severe hypoglycaemia: usually when combined with insulin or secretagogues.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Allergic reactions: rash, pruritus, or angio‑edema.
  • Pancreatitis: inflammation of the pancreas.
  • Electrolyte disturbances: especially in renal impairment.

Precautions & Warnings

Metformin Vitabalans requires careful monitoring in several clinical situations.

  • Renal function: avoid or adjust dose in patients with impaired creatinine clearance.
  • Hepatic disease: use with caution; monitor liver enzymes.
  • Lactic acidosis risk: discontinue before surgeries or iodinated contrast studies.
  • Pregnancy and lactation: assess risk‑benefit; use only if clearly needed.
  • Vitamin B12 monitoring: check levels periodically during long‑term therapy.
  • Store at ambient temperature (below 25°C): keep in the original container, protect from moisture and light.

Avoid Interactions

Metformin Vitabalans can interact with several medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Iodinated contrast media (radiographic): may precipitate lactic acidosis; withhold metformin before and after the procedure.
  • Cimetidine: can increase metformin plasma concentrations, raising toxicity risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may affect renal function, requiring dose adjustment.
  • Diuretics: can lead to dehydration and reduced renal clearance of metformin.
  • Alcohol: excessive intake increases lactic acidosis risk.
  • Beta‑blockers: may mask hypoglycaemia symptoms when combined with insulin secretagogues.

Frequently Asked Questions

Metformin Vitabalans is an oral biguanide indicated primarily for the management of type 2 diabetes mellitus. It helps lower elevated blood glucose by improving insulin sensitivity and reducing hepatic glucose production, supporting long‑term glycaemic control in adults.

Metformin Hydrochloride activates AMP‑activated protein kinase (AMPK) in liver and muscle cells. This activation suppresses gluconeogenesis in the liver, reduces intestinal glucose absorption, and enhances peripheral uptake of glucose, thereby decreasing overall blood glucose levels without increasing insulin secretion.

The specific dose of Metformin Vitabalans is determined by the prescribing clinician based on the patient’s clinical condition, renal function, and response to therapy. Dosage adjustments are made individually and should follow the prescriber’s instructions.

Safety of Metformin Vitabalans in pregnancy or lactation should be evaluated by a healthcare professional. It may be used when the potential benefit justifies the potential risk, but the prescriber must assess each case and provide appropriate guidance.

To order Metformin Vitabalans, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metformin Vitabalans belongs to the biguanide class, differing from sulfonylureas, DPP‑4 inhibitors, or SGLT2 inhibitors. Unlike insulin‑secretagogues, it does not stimulate insulin release, reducing hypoglycaemia risk. Its weight‑neutral or modest weight‑loss effect and low cost make it a first‑line option in many treatment guidelines.

Metformin Vitabalans should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Metformin Vitabalans is taken orally, usually with meals to minimise gastrointestinal discomfort. The tablets are swallowed whole with a glass of water; they should not be crushed, chewed, or dissolved unless specifically instructed by a healthcare professional.

The most serious risk is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal or hepatic impairment, or after exposure to iodinated contrast media. Prompt medical attention is required if symptoms such as unexplained fatigue, rapid breathing, or abdominal pain develop.

Metformin Vitabalans is contraindicated in patients with known hypersensitivity to metformin, severe renal impairment (eGFR <30 mL/min/1.73 m²), acute or chronic metabolic acidosis, including diabetic ketoacidosis, and in those who have received iodinated contrast agents within the preceding 48 hours.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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