Product image of Metformin Xr Teva (Metformin Hydrochloride) supplied by GNH India

Metformin Xr Teva

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Metformin Xr Teva (Metformin Hydrochloride)

Metformin Hydrochloride, the active ingredient in Metformin XR Teva, is a biguanide presented as an extended‑release tablet for oral use. It is employed to lower elevated blood glucose levels in adults with type 2 diabetes mellitus.

GNH India supplies Metformin XR Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Our distribution network ensures timely delivery and reliable product integrity across diverse markets.

Manufacturer / TM Owner

Teva B.V

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metformin XR Teva is a biguanide indicated for the management of type 2 diabetes mellitus, a chronic disorder of glucose metabolism.

  • Type 2 diabetes mellitus: improves glycemic control by lowering fasting and post‑prandial blood glucose levels.

How It Works

  • Metformin Hydrochloride acts primarily by inhibiting hepatic gluconeogenesis, thereby decreasing hepatic glucose output. It also reduces intestinal glucose absorption and enhances peripheral insulin sensitivity, facilitating greater glucose uptake by muscle and adipose tissue without stimulating insulin secretion.

Side Effects

Metformin XR Teva may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, often early in therapy.
  • Abdominal discomfort: cramping or bloating.
  • Metallic taste: transient alteration of taste perception.
  • Loss of appetite: reduced desire to eat.
  • Flatulence: increased intestinal gas.

Serious or Rare Side Effects

  • Lactic acidosis: rare but life‑threatening metabolic disturbance.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.
  • Hepatic failure: marked liver dysfunction.
  • Hypoglycemia: uncommon when used alone.
  • Vitamin B12 deficiency: may develop with long‑term use.
  • Pancreatitis: rare inflammation of the pancreas.

Precautions & Warnings

Metformin XR Teva requires careful consideration of patient‑specific factors and clinical monitoring.

  • Renal function: avoid or adjust dose in patients with impaired renal clearance.
  • Hepatic impairment: use with caution in liver disease.
  • Lactic acidosis risk: discontinue if signs of metabolic acidosis appear.
  • Alcohol consumption: limit intake to reduce acidosis risk.
  • Contrast imaging: suspend therapy before iodinated contrast procedures.
  • Pregnancy category B: use only if clearly needed.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metformin XR Teva can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Iodinated contrast agents: may precipitate acute renal failure and lactic acidosis.
  • Cimetidine: can increase metformin plasma concentrations.
  • Alcohol: potentiates risk of lactic acidosis.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask hypoglycemia symptoms.
  • Diuretics: can affect renal function and metformin clearance.
  • ACE inhibitors/ARBs: monitor renal function and electrolytes.
  • Other antidiabetic agents: adjust dosing to avoid hypoglycemia.
  • Thyroid hormones: may require glucose monitoring.

Frequently Asked Questions

Metformin XR Teva is an extended‑release formulation of metformin hydrochloride indicated for the treatment of type 2 diabetes mellitus in adults. It helps lower elevated blood glucose levels by improving the body’s response to insulin and reducing glucose production in the liver.

Metformin Hydrochloride reduces hepatic glucose output, decreases intestinal absorption of glucose, and enhances peripheral insulin sensitivity. These actions collectively lower fasting and post‑prandial blood glucose without stimulating insulin secretion, making it effective for managing type 2 diabetes.

The dosage of Metformin XR Teva is individualized by the prescribing healthcare professional based on the patient’s clinical condition, renal function, and response to therapy. The prescriber determines the appropriate strength and dosing schedule.

Metformin XR Teva is classified as pregnancy category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during pregnancy only if the potential benefit justifies the potential risk. Breastfeeding mothers should consult their physician, as metformin is excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details, and any necessary import documentation.

Metformin XR provides a once‑daily extended‑release delivery, which can improve gastrointestinal tolerability and adherence compared with immediate‑release formulations that are typically taken two to three times daily. Both contain the same active ingredient and have comparable efficacy when dosed appropriately.

Store Metformin XR Teva at ambient temperature below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed to maintain product stability.

Metformin XR Teva is taken orally, usually once daily with the evening meal. Tablets should be swallowed whole with a full glass of water; they must not be split, chewed, or crushed, as this can disrupt the extended‑release mechanism.

The most serious risk is lactic acidosis, a rare but potentially fatal condition characterized by rapid breathing, muscle pain, and abdominal discomfort. Prompt medical attention is required if these symptoms occur. Other serious concerns include severe skin reactions and hepatic dysfunction.

Metformin XR Teva is contraindicated in patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²), known hypersensitivity to metformin, acute or chronic metabolic acidosis, and those who have experienced lactic acidosis while on metformin. Caution is also advised for individuals with hepatic disease or significant alcohol use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.