Product image of Metformine Eg Labo (Metformin Hydrochloride) supplied by GNH India

Metformine Eg Labo

Active Ingredient:
Metformin Hydrochloride
Origin:
EU

Metformine Eg Labo (Metformin Hydrochloride)

Metformin, the active ingredient in Metformine Eg Labo, is a biguanide presented as an oral tablet for oral use. It is used to improve glycaemic control in adults with type 2 diabetes mellitus.\n\nGNH India supplies Metformine Eg Labo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

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Indications & Clinical Uses

  • Metformine Eg Labo (metformin) belongs to the biguanide class and is employed in the management of disorders related to insulin resistance and hyperglycaemia.\n\nType 2 diabetes mellitus: improves blood glucose control and reduces HbA1c levels.\nPrediabetes: helps delay progression to overt diabetes by enhancing insulin sensitivity.\nPolycystic ovary syndrome (PCOS): reduces insulin resistance and may improve menstrual regularity.

How It Works

  • Metformin primarily inhibits hepatic gluconeogenesis, decreasing the liver's production of glucose. It also enhances peripheral glucose uptake by increasing insulin sensitivity in muscle and adipose tissue, and modestly reduces intestinal absorption of glucose, collectively contributing to lower plasma glucose concentrations.

Side Effects

  • Metformine Eg Labo is generally well tolerated, but adverse reactions can occur.\n\nCommon Side Effects:\n- Nausea\n- Diarrhoea\n- Abdominal discomfort\n- Metallic taste\n- Loss of appetite\n- Flatulence\n\nSerious or Rare Side Effects:\n- Lactic acidosis (life‑threatening)\n- Severe skin reactions such as Stevens‑Johnson syndrome\n- Hepatic dysfunction\n- Vitamin B12 deficiency with long‑term use\n- Hypoglycaemia when combined with other glucose‑lowering agents\n- Acute pancreatitis (rare)

Precautions & Warnings

  • Before initiating Metformine Eg Labo, several safety considerations should be reviewed.\n\nRenal function monitoring: assess eGFR and adjust dose or discontinue if severely impaired.\nHepatic function assessment: avoid use in active liver disease due to lactic acidosis risk.\nRisk of lactic acidosis: evaluate for conditions that predispose, such as hypoxia or sepsis.\nConcomitant medication review: avoid drugs that may increase metformin levels or lactic acidosis risk.\nPatient education: inform about gastrointestinal symptoms and advise to report persistent issues.\nStore at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

  • Metformine Eg Labo may interact with several medicines, requiring attention to avoid adverse outcomes.\n\nMajor Interactions (Avoid):\n- Iodinated contrast agents: can precipitate acute renal failure and lactic acidosis.\n- Cimetidine: may increase metformin plasma concentrations.\n- Alcohol excess: heightens risk of lactic acidosis.\n\nModerate Interactions (Monitor Closely):\n- Beta‑blockers: may mask hypoglycaemia symptoms.\n- Diuretics: can affect renal clearance of metformin.\n- NSAIDs: may impair renal function and increase metformin exposure.

Frequently Asked Questions

Metformine Eg Labo is a generic formulation of metformin hydrochloride indicated for the management of type 2 diabetes mellitus in adults. It helps lower elevated blood glucose levels by improving the body’s response to insulin and reducing hepatic glucose production.

Metformin acts mainly by inhibiting hepatic gluconeogenesis, which reduces the amount of glucose released by the liver. It also increases peripheral insulin sensitivity, enhancing glucose uptake in muscle and fat tissue, and modestly decreases intestinal glucose absorption, together improving overall glycaemic control.

The exact dose of Metformine Eg Labo is determined by the prescribing healthcare professional based on the patient’s individual clinical profile, renal function, and glycaemic targets. Dosage may be started low and titrated upward as needed, following established clinical guidelines.

Safety of metformin in pregnancy and lactation has not been fully established. It may be used during pregnancy only if the potential benefit outweighs the risk, and breastfeeding mothers should discuss alternatives with their clinician, as metformin can be excreted in breast milk.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metformin belongs to the biguanide class and is generally preferred as first‑line therapy for type 2 diabetes because it does not cause weight gain and has a low risk of hypoglycaemia compared with sulfonylureas or insulin. It may be combined with other agents when additional glucose lowering is required.

Metformine Eg Labo should be stored at ambient temperature, below 25 °C, in the original container to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the packaging.

The medication is taken orally, usually with meals to minimise gastrointestinal discomfort. Tablets should be swallowed whole with a full glass of water and not crushed or chewed unless otherwise directed by a healthcare professional.

The most serious adverse effect is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal or hepatic impairment, hypoxia, or excessive alcohol intake. Prompt medical attention is required if symptoms such as rapid breathing, muscle pain, or abdominal discomfort develop.

Metformine Eg Labo is contraindicated in individuals with severe renal impairment (eGFR < 30 mL/min/1.73 m²), acute or chronic metabolic acidosis, known hypersensitivity to metformin, or those receiving radiographic contrast studies without adequate renal monitoring.

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GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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