Product image of Methadone Hydrochloride Sugar Free Rosemont Pharmaceuticals (Methadone Hydrochloride Ph. Eur.) supplied by GNH India

Methadone Hydrochloride Sugar Free Rosemont Pharmaceuticals

Active Ingredient:
Methadone Hydrochloride Ph. Eur.
Origin:
EU

Methadone Hydrochloride Sugar Free Rosemont Pharmaceuticals (Methadone Hydrochloride Ph. Eur.)

Methadone Hydrochloride, the active ingredient in Methadone Hydrochloride Sugar Free Rosemont Pharmaceuticals, is an opioid presented as a sugar‑free oral formulation for oral use. It is used to treat opioid dependence and manage chronic pain in appropriate patients.

GNH India supplies Methadone Hydrochloride Sugar Free Rosemont Pharmaceuticals as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Rosemont Pharmaceuticals Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Methadone Hydrochloride is an opioid agonist used in the management of opioid dependence and chronic pain.
  • Opioid dependence: reduces withdrawal symptoms and cravings during maintenance therapy.
  • Chronic pain: provides long‑acting analgesia for severe, persistent pain.
  • Detoxification: facilitates medically supervised opioid withdrawal under clinical supervision.

How It Works

  • Methadone Hydrochloride acts as a full agonist at the mu‑opioid receptor, binding with high affinity and producing analgesic and euphoric effects while suppressing withdrawal. By activating these receptors, it decreases neuronal excitability and modulates pain pathways, leading to sustained analgesia and reduced opioid craving.

Side Effects

Methadone Hydrochloride may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Constipation: reduced gastrointestinal motility.
  • Nausea: mild to moderate upset stomach.
  • Dizziness: sensation of light‑headedness.
  • Drowsiness: increased sleepiness.
  • Sweating: excessive perspiration.

Serious or Rare Side Effects

  • Respiratory depression: slowed breathing that can be life‑threatening.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Adrenal insufficiency: rare hormonal imbalance.
  • Severe hypotension: marked drop in blood pressure.

Precautions & Warnings

  • When prescribing Methadone Hydrochloride, clinicians should observe several safety measures.
  • Dose titration: adjust dose gradually under medical supervision.
  • Respiratory status: monitor patients with compromised breathing.
  • Cardiac risk: assess QT interval in patients with cardiac disease.
  • Pregnancy: category C, use only if benefits outweigh risks.
  • Drug dependence: risk of misuse, monitor closely.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Methadone Hydrochloride interacts with several medication classes; awareness of these interactions helps prevent adverse events.

Major Interactions (Avoid)

  • CYP3A4 inhibitors: may increase methadone levels and risk of toxicity.
  • QT‑prolonging agents: additive risk of cardiac arrhythmias.
  • Central nervous system depressants: enhanced respiratory depression.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers: may reduce methadone efficacy.
  • Serotonergic drugs: potential for serotonin syndrome.
  • Alcohol: may increase sedation and respiratory effects.

Frequently Asked Questions

Methadone Hydrochloride Sugar Free is used primarily for opioid dependence treatment and for managing chronic pain in patients who require long‑acting opioid analgesia.

Methadone Hydrochloride acts as a full agonist at the mu‑opioid receptor, binding to these receptors to produce analgesia, suppress withdrawal symptoms, and reduce cravings in opioid‑dependent individuals.

The appropriate dose of Methadone Hydrochloride is determined by the prescribing clinician based on the patient’s condition, prior opioid exposure, and response to therapy.

Methadone Hydrochloride is classified as pregnancy category C; it should be used only if the potential benefit justifies the potential risk to the fetus. Limited data are available for breastfeeding, and a healthcare professional should evaluate the risk‑benefit ratio.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Methadone Hydrochloride provides a long‑acting oral option that can be titrated for maintenance therapy, whereas alternatives such as buprenorphine have a ceiling effect and may be administered sublingually or as a film. Choice depends on clinical goals, patient preference and regulatory considerations.

Store the product at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and extreme heat to maintain stability.

Methadone Hydrochloride is administered orally, typically as a tablet or liquid, and should be taken exactly as prescribed, with or without food, according to the dosing schedule set by the healthcare provider.

The most serious risks include respiratory depression, especially in opioid‑naïve patients or when combined with other depressants, and QT interval prolongation, which can lead to potentially fatal cardiac arrhythmias.

Patients with known hypersensitivity to methadone, uncontrolled severe respiratory disease, significant cardiac conduction abnormalities, or those taking contraindicated medications should not use Methadone Hydrochloride.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Methadone Hydrochloride Ph. Eur.

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT