Metida (Dimetindene Maleate)

Dimetindene Maleate works by selectively blocking peripheral H1 histamine receptors on mast cells and sensory nerves. This antagonism prevents histamine‑induced vasodilation, increased vascular permeability and the activation of itch pathways, thereby decreasing edema, erythema and the sensation of itching at the site of application.

The appropriate amount of Metida is determined by the prescribing healthcare professional. Typically, a thin layer is applied to the affected area once or twice daily, but the exact frequency and quantity depend on the severity of the condition, patient age and the extent of skin involvement.

Safety of Dimetindene Maleate in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Metida, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Metida (Dimetindene Maleate) is a first‑generation H1 antagonist with a rapid onset of action and a relatively low risk of systemic sedation when used topically. Compared with agents such as diphenhydramine cream, Dimetindene often provides comparable itch relief with less skin dryness, while newer second‑generation agents like cetirizine are typically available only in oral form.

Metida should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain stability.

Metida is applied topically to clean, dry skin. A thin layer is spread over the affected area and gently massaged in until absorbed. The frequency of application—usually once or twice daily—should follow the prescribing clinician’s instructions.

Serious risks, though rare, include allergic contact dermatitis, angioedema and systemic hypersensitivity reactions such as urticaria or anaphylactoid responses. Patients should discontinue use and seek medical attention if they experience severe swelling, difficulty breathing, or a widespread rash.

Metida should be avoided in individuals with known hypersensitivity to dimetindene or any excipients in the formulation. It is also contraindicated for children under two years of age unless specifically directed by a physician, and caution is advised in patients with severe hepatic impairment.