Product image of Metigalen Lotion (Methylprednisolone Aceponate) supplied by GNH India

Metigalen Lotion

Active Ingredient:
Methylprednisolone Aceponate
Origin:
EU

Metigalen Lotion (Methylprednisolone Aceponate)

Methylprednisolone aceponate, the active ingredient in Metigalen Lotion, is a corticosteroid presented as a topical lotion for skin use. It treats inflammatory skin conditions such as eczema, atopic dermatitis, psoriasis and allergic reactions in patients requiring anti‑inflammatory therapy.

GNH India supplies Metigalen Lotion as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Galenpharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metigalen Lotion, a topical corticosteroid, is used to manage inflammatory skin disorders.

  • Eczema: reduces redness, itching and swelling associated with the condition.
  • Atopic dermatitis: alleviates chronic inflammation and improves skin barrier function.
  • Psoriasis: diminishes plaque formation and scaling.
  • Allergic skin reactions: suppresses acute allergic inflammation and pruritus.

How It Works

  • Methylprednisolone aceponate binds to intracellular glucocorticoid receptors in keratinocytes and immune cells, forming a complex that translocates to the nucleus and modulates gene transcription. This down‑regulates pro‑inflammatory cytokines, chemokines and adhesion molecules while up‑regulating anti‑inflammatory proteins, leading to reduced inflammation and immune activity in the treated skin area.

Side Effects

Topical application of Metigalen Lotion may be associated with local and systemic adverse reactions.

Common Side Effects

  • Skin irritation or burning sensation.
  • Pruritus or mild itching.
  • Dryness or flaking of the treated area.
  • Folliculitis or acneiform eruptions.
  • Erythema or mild redness.
  • Contact dermatitis.

Serious or Rare Side Effects

  • Skin atrophy or thinning.
  • Telangiectasia (visible small blood vessels).
  • Secondary bacterial, fungal or viral infection.
  • Systemic adrenal suppression.
  • Cushing's syndrome with prolonged use.
  • Severe hypersensitivity reactions such as angioedema.

Precautions & Warnings

When using Metigalen Lotion, consider the following safety measures.

  • Apply only to intact skin: avoid broken or infected areas.
  • Limit duration of use: follow prescriber guidance to reduce risk of skin atrophy.
  • Avoid use on large body surface areas: may increase systemic absorption.
  • Do not use under occlusive dressings unless directed: can enhance potency.
  • Pregnancy and lactation: discuss risks with a healthcare provider.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Metigalen Lotion may interact with other medications; monitor accordingly.

Major Interactions (Avoid)

  • Systemic glucocorticoids: concurrent use may increase risk of systemic corticosteroid side effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise systemic exposure of the steroid.
  • Live vaccines: systemic absorption could reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Topical antifungal agents (azoles): may affect skin barrier and alter absorption.
  • Topical NSAIDs applied to the same area: may increase local irritation.
  • Phototherapy: combined use may enhance skin thinning and sensitivity.

Frequently Asked Questions

Metigalen Lotion is prescribed for inflammatory skin disorders such as eczema, atopic dermatitis, psoriasis and allergic skin reactions. It helps to reduce redness, itching, swelling and scaling associated with these conditions.

Methylprednisolone aceponate binds to glucocorticoid receptors in skin cells, altering gene transcription. This suppresses the production of pro‑inflammatory cytokines and mediators while enhancing anti‑inflammatory proteins, resulting in decreased inflammation and immune activity in the affected area.

The prescribed dose of Metigalen Lotion is set by the treating clinician based on the severity of the skin condition, the size of the affected area, patient age and response to therapy. No fixed regimen can be provided without a medical assessment.

Safety data for methylprednisolone aceponate in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To request Metigalen Lotion, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metigalen Lotion contains methylprednisolone aceponate, a mid‑potency corticosteroid, offering a balance between efficacy and safety. Compared with lower‑potency agents it provides stronger anti‑inflammatory action, while higher‑potency steroids may carry greater risk of skin atrophy when used long‑term.

Metigalen Lotion should be stored at room temperature, below 25 °C, in its original container. Keep it away from direct sunlight, excessive heat and moisture to maintain product stability.

Clean and gently dry the affected skin area. Apply a thin, even layer of Metigalen Lotion to the lesion and rub in gently. Use only the amount directed by the prescriber and avoid covering the area with occlusive dressings unless instructed.

Serious risks include skin atrophy, telangiectasia, secondary infections, systemic adrenal suppression and, with prolonged use, signs of Cushing's syndrome. If any of these occur, discontinue use and seek medical advice promptly.

Metigalen Lotion is contraindicated in individuals with known hypersensitivity to methylprednisolone aceponate or any excipients, as well as in patients with untreated viral, fungal or bacterial skin infections, and in areas of skin affected by rosacea or acne that could worsen with steroid use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Methylprednisolone Aceponate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT