Product image of Metildrol (Methylprednisolone) supplied by GNH India

Metildrol

Active Ingredient:
Methylprednisolone
Origin:
EU

Metildrol (Methylprednisolone)

Methylprednisolone, the active ingredient in Metildrol, is a corticosteroid presented as an oral tablet for oral use. It provides anti‑inflammatory and immunosuppressive effects for conditions such as rheumatoid arthritis, asthma, and other autoimmune disorders.

GNH India supplies Metildrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

So.Se.Pharm S.R.L.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metildrol, a glucocorticoid, is employed to control inflammation and immune‑mediated disease processes.

  • Rheumatoid arthritis: reduces joint inflammation, pain, and swelling.
  • Asthma: diminishes airway inflammation and improves breathing.
  • Allergic reactions: alleviates severe allergic symptoms and edema.
  • Dermatologic inflammatory conditions: controls skin inflammation such as eczema or psoriasis flares.
  • Autoimmune diseases: suppresses abnormal immune activity in conditions like systemic lupus erythematosus.

How It Works

  • Methylprednisolone binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action up‑regulates anti‑inflammatory proteins and down‑regulates pro‑inflammatory cytokines, leading to reduced leukocyte migration, decreased capillary permeability, and overall immunosuppression.

Side Effects

Adverse reactions may occur with systemic corticosteroid therapy.

Common Side Effects

  • Increased appetite and weight gain.
  • Insomnia or mood changes.
  • Elevated blood glucose levels.
  • Gastrointestinal discomfort or dyspepsia.
  • Fluid retention and mild edema.
  • Skin thinning or easy bruising.

Serious or Rare Side Effects

  • Adrenal insufficiency on abrupt discontinuation.
  • Severe infections, including opportunistic pathogens.
  • Osteoporosis with long‑term use.
  • Cataracts or glaucoma.
  • Psychosis or severe mood disorders.
  • Anaphylaxis or severe allergic reaction.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess infection risk: evaluate for active bacterial, viral, or fungal infections.
  • Monitor blood glucose: patients with diabetes may need tighter control.
  • Review bone health: consider calcium and vitamin D supplementation for long‑term use.
  • Evaluate psychiatric history: corticosteroids can exacerbate mood disorders.
  • Check vaccination status: avoid live vaccines during treatment.
  • Store below 25°C: keep in the original pack, protect from moisture and light.

Avoid Interactions

Methylprednisolone can alter the effects of several concomitant medicines.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase systemic exposure.
  • Live vaccines: heightened risk of severe infection.
  • Anticoagulants (e.g., warfarin): potential enhancement of anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Antidiabetic agents: may require dose adjustments due to hyperglycemia.
  • NSAIDs: increased risk of gastrointestinal ulceration or bleeding.
  • Non‑live vaccines: possible reduced immunogenic response, monitor efficacy.

Frequently Asked Questions

Metildrol contains methylprednisolone, a corticosteroid used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis, asthma, severe allergic reactions, dermatologic inflammatory disorders, and other systemic autoimmune diseases.

Methylprednisolone binds to intracellular glucocorticoid receptors, altering gene transcription. This up‑regulates anti‑inflammatory proteins and down‑regulates pro‑inflammatory cytokines, resulting in reduced immune cell activation, decreased vascular permeability, and overall suppression of inflammation.

The appropriate dose of Metildrol is determined individually by a qualified prescriber based on the specific condition, severity, patient weight, and response to therapy. Patients should follow the dosing instructions provided by their healthcare professional.

Safety data for methylprednisolone in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made in consultation with a healthcare provider.

To order Metildrol, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metildrol (methylprednisolone) is a more potent glucocorticoid than prednisone on a milligram‑for‑milligram basis, offering stronger anti‑inflammatory effects with a shorter duration of action. Choice between agents depends on clinical judgment, dosing convenience, and patient‑specific factors.

Metildrol should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct light. Keep the product out of reach of children and do not use if the packaging is damaged.

Metildrol is taken orally, usually with a full glass of water. It may be taken with or without food, but patients should follow any specific instructions from their prescriber regarding timing relative to meals.

Serious risks include adrenal insufficiency if the drug is stopped abruptly, severe infections, osteoporosis with long‑term use, cataracts or glaucoma, and rare psychiatric effects such as psychosis. Patients should be monitored closely for these complications.

Metildrol is contraindicated in patients with known hypersensitivity to methylprednisolone or any component of the formulation, those with systemic fungal infections, and individuals receiving live vaccines. Caution is also advised for patients with uncontrolled diabetes, severe hypertension, or active peptic ulcer disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Methylprednisolone

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT