Product image of Metobeta (Metoprolol Tartrate) supplied by GNH India

Metobeta

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metobeta (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metobeta, is a beta blocker presented as an oral tablet for oral use. It treats hypertension, angina pectoris, post‑myocardial infarction and chronic heart failure in adult patients.

GNH India supplies Metobeta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Betapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Metobeta is a selective β1‑adrenergic blocker used in cardiovascular conditions where reduction of heart rate and myocardial workload is required.

  • Hypertension: lowers systolic and diastolic pressure by decreasing cardiac output.
  • Angina pectoris: reduces myocardial oxygen demand, relieving chest pain during exertion.
  • Post‑myocardial infarction: improves survival by limiting arrhythmias and remodeling.
  • Chronic heart failure: enhances ventricular function and decreases hospitalization risk.

How It Works

  • Metoprolol Tartrate selectively antagonizes β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This action reduces heart rate, myocardial contractility, and conduction velocity, leading to decreased cardiac output and lower arterial pressure, while also diminishing myocardial oxygen consumption.

Side Effects

Metobeta may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue: feeling of tiredness or lack of energy.
  • Dizziness: light‑headed sensation, especially on standing.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced blood flow to hands and feet.
  • Gastrointestinal upset: nausea, abdominal discomfort.
  • Sleep disturbances: insomnia or vivid dreams.

Serious or Rare Side Effects

  • Severe bradycardia or heart block requiring medical attention.
  • Marked hypotension leading to fainting.
  • Bronchospasm in patients with reactive airway disease.
  • Allergic reactions such as rash, itching, or angioedema.
  • Depression or mood changes.
  • Worsening heart failure symptoms.

Precautions & Warnings

When prescribing Metobeta, clinicians should consider several safety measures.

  • Monitor blood pressure: check regularly to avoid excessive hypotension.
  • Assess heart rate: ensure rate remains within therapeutic range.
  • Use caution in asthma or COPD: β1‑selectivity may not fully prevent bronchoconstriction.
  • Avoid abrupt discontinuation: taper dose to prevent rebound tachycardia.
  • Adjust dose in renal impairment: reduced clearance may increase drug exposure.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and light.

Avoid Interactions

Metobeta can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Non‑selective beta blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): may cause severe heart block.
  • Clonidine: abrupt withdrawal can precipitate hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Diuretics: risk of excessive blood pressure reduction.
  • ACE inhibitors or ARBs: potential for marked hypotension.
  • Antidepressants (SSRIs, SNRIs): may increase bradycardia risk.
  • NSAIDs: can blunt antihypertensive effect.

Frequently Asked Questions

Metobeta contains metoprolol tartrate, a beta‑blocker indicated for managing high blood pressure, relieving angina pectoris, reducing the risk of further events after a heart attack, and improving outcomes in chronic heart failure. It works by lowering heart rate and cardiac workload, which helps control these cardiovascular conditions.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart. By preventing catecholamines from binding, it slows the heart rate, reduces the force of contraction, and lowers cardiac output. This results in decreased arterial pressure and reduced myocardial oxygen demand, which are beneficial in hypertension, angina, and heart failure.

The appropriate dose of Metobeta is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and any co‑existing health issues. Dosage may be started low and adjusted gradually; patients should follow the specific instructions provided by their healthcare professional.

Safety data for metoprolol tartrate in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will evaluate each case individually and discuss alternatives when appropriate.

To request Metobeta, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metobeta (metoprolol tartrate) is a cardio‑selective β1‑blocker, offering a favorable profile for patients with hypertension, angina, or heart failure. Compared with non‑selective beta blockers, it has a lower risk of bronchospasm in patients with respiratory disease, while still providing effective heart rate control.

Metobeta should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, direct sunlight, and heat sources to maintain stability and potency throughout its shelf life.

Metobeta is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the prescribing clinician’s guidance on timing and whether to split or crush tablets, if applicable.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in susceptible individuals, and rare allergic reactions such as angioedema. Patients should seek immediate medical attention if they experience fainting, extreme fatigue, difficulty breathing, or swelling of the face or throat.

Metobeta is contraindicated in patients with known hypersensitivity to metoprolol or other beta blockers, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and individuals experiencing uncompensated heart failure or cardiogenic shock. Clinicians must assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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