Product image of Metocar (Metoprolol Tartrate) supplied by GNH India

Metocar

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metocar (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metocar, is a beta‑blocker presented as an oral dosage form for oral use. It is employed to manage high blood pressure, relieve angina, improve outcomes after myocardial infarction, treat certain heart failure patients, and control cardiac arrhythmias.

GNH India supplies Metocar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution.

Manufacturer / TM Owner

Stada Nordic Aps

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Indications & Clinical Uses

Metocar, a selective β1‑adrenergic blocker, is used in several cardiovascular conditions.

  • Hypertension: lowers systolic and diastolic blood pressure, reducing cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Post‑myocardial infarction: improves survival and reduces recurrent ischemic events.
  • Heart failure: enhances left‑ventricular function and decreases hospitalization.
  • Cardiac arrhythmias: stabilises heart rhythm by slowing conduction through the AV node.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, leading to reduced heart rate, decreased myocardial contractility, and lowered renin release from the kidneys. This combined effect diminishes cardiac output and peripheral vascular resistance, contributing to blood‑pressure control and decreased myocardial oxygen consumption.

Side Effects

Metocar may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue: feeling of tiredness or lack of energy.
  • Dizziness: light‑headed sensation, especially on standing.
  • Cold extremities: reduced blood flow to hands and feet.
  • Bradycardia: slower than normal heart rate.
  • Gastrointestinal upset: nausea, abdominal discomfort.
  • Sleep disturbances: insomnia or vivid dreams.

Serious or Rare Side Effects

  • Severe bradycardia: markedly low heart rate requiring medical attention.
  • Hypotension: dangerously low blood pressure.
  • Heart block: impaired electrical conduction in the heart.
  • Bronchospasm: narrowing of airways, particularly in patients with asthma.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Depression or mood changes: worsening of depressive symptoms.

Precautions & Warnings

Before initiating Metocar, consider the following safety measures.

  • Renal impairment: assess kidney function and adjust dose if necessary.
  • Hepatic dysfunction: monitor liver enzymes and consider dose modification.
  • Asthma or chronic obstructive pulmonary disease: use with caution due to potential bronchoconstriction.
  • Diabetes: monitor blood glucose as beta‑blockers may mask hypoglycaemia symptoms.
  • Concomitant AV‑node blocking agents: evaluate for additive bradycardia risk.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Metocar can interact with several medication classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: may cause excessive bradycardia.
  • Calcium channel blockers (verapamil, diltiazem): increase risk of heart block and hypotension.
  • Antihypertensive agents (ACE inhibitors, diuretics): additive blood‑pressure lowering effect.

Moderate Interactions (Monitor Closely)

  • Antidiabetic drugs (insulin, sulfonylureas): may mask hypoglycaemia signs.
  • Antidepressants (SSRIs, SNRIs): potential for increased bradycardia.
  • NSAIDs: may reduce antihypertensive efficacy.
  • Antithyroid medications: may enhance beta‑blocker effects on heart rate.

Frequently Asked Questions

Metocar contains metoprolol tartrate, a beta‑blocker indicated for hypertension, angina pectoris, post‑myocardial infarction management, heart failure, and certain cardiac arrhythmias. It helps lower blood pressure, reduce chest pain, improve survival after a heart attack, support heart‑failure therapy, and stabilise abnormal heart rhythms.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, which reduces heart rate, myocardial contractility, and renin release. This leads to decreased cardiac output and lower peripheral resistance, helping to control blood pressure and reduce the heart’s oxygen demand.

The appropriate dose of Metocar is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Dosage may be adjusted over time to achieve the desired therapeutic effect while minimising side effects.

Safety of metoprolol tartrate during pregnancy or lactation has not been definitively established. Healthcare providers should weigh potential benefits against possible risks and consider alternative therapies when appropriate. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their physician.

To request Metocar, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Metocar (metoprolol tartrate) is a cardio‑selective β1‑blocker, offering targeted heart effects with fewer respiratory side effects compared with non‑selective agents like propranolol. Its pharmacokinetic profile provides reliable blood‑pressure control and is often preferred for patients with asthma or chronic obstructive pulmonary disease.

Metocar should be stored below 25 °C in its original container, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiration date printed on the packaging.

Metocar is taken orally, usually with or without food, as directed by the prescribing clinician. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include severe bradycardia, marked hypotension, heart block, bronchospasm in susceptible individuals, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience fainting, rapid weight gain, swelling of the ankles, or difficulty breathing.

Metocar is contraindicated in patients with known hypersensitivity to metoprolol or any excipients, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, cardiogenic shock, or overt heart failure decompensation. Caution is also advised for individuals with severe asthma or chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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