Product image of Metoclopramida Ipca (Metoclopramide Hydrochloride) supplied by GNH India

Metoclopramida Ipca

Active Ingredient:
Metoclopramide Hydrochloride
Origin:
EU

Metoclopramida Ipca (Metoclopramide Hydrochloride)

Metoclopramide, the active ingredient in Metoclopramida Ipca, is a dopamine D2 receptor antagonist presented as an oral dosage form for oral use. It is employed to improve gastric emptying and to reduce nausea and vomiting in a variety of clinical settings.

GNH India supplies Metoclopramida Ipca as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ipca Productos Farmaceuticos Unipessoal Lda

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metoclopramida acts on the gastrointestinal tract and the chemoreceptor trigger zone to alleviate symptoms related to motility and emesis.

  • Nausea and vomiting: reduces episodes of nausea and vomiting in postoperative, chemotherapy‑induced and other settings.
  • Gastroparesis: enhances gastric emptying and alleviates delayed stomach emptying.
  • Gastro‑esophageal reflux disease (GERD): improves lower esophageal sphincter tone and reduces reflux symptoms.
  • Migraine‑associated nausea: mitigates nausea accompanying migraine attacks.

How It Works

  • Metoclopramide hydrochloride antagonizes dopamine D2 receptors in the chemoreceptor trigger zone and throughout the gastrointestinal tract. This blockade increases acetylcholine release, promoting coordinated gastric contractions, accelerating gastric emptying, and diminishing the central perception of nausea and vomiting.

Side Effects

Metoclopramida may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Restlessness: a sense of inner tension or inability to stay still.
  • Diarrhea: loose, frequent stools.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Extrapyramidal reactions: involuntary muscle movements or dystonia.
  • Tardive dyskinesia: persistent, irreversible facial or limb movements.
  • Neuroleptic malignant syndrome: life‑threatening fever, rigidity, and autonomic instability.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Assess renal function: dose adjustment may be required in renal impairment.
  • Monitor for extrapyramidal symptoms: watch for muscle rigidity or abnormal movements.
  • Avoid in patients with known hypersensitivity to metoclopramide or its excipients.
  • Use caution in the elderly: increased susceptibility to central nervous system effects.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Metoclopramida can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Antipsychotics (e.g., haloperidol): heightened risk of extrapyramidal symptoms.
  • CYP2D6 inhibitors (e.g., fluoxetine): increased metoclopramide plasma concentrations.
  • MAO inhibitors: potential for hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Anticholinergics: may diminish the pro‑kinetic effect of metoclopramide.
  • Sedatives (e.g., benzodiazepines): additive central nervous system depression.

Frequently Asked Questions

Metoclopramida Ipca contains metoclopramide, which is prescribed to treat nausea and vomiting, improve gastric emptying in gastroparesis, reduce reflux symptoms in gastro‑esophageal reflux disease, and alleviate nausea associated with migraine attacks.

Metoclopramide blocks dopamine D2 receptors in the chemoreceptor trigger zone and the gastrointestinal tract. This action increases acetylcholine release, enhancing coordinated stomach contractions, speeding gastric emptying, and decreasing the brain’s perception of nausea.

The specific dose is determined by the prescribing clinician based on the patient’s condition, age, renal function and response to therapy. Typical adult regimens range from 5 mg to 10 mg taken several times daily, but exact dosing must follow the prescriber’s order.

Safety data for metoclopramide in pregnancy are limited, and the drug is classified as Category C in many regions. It should only be used when the potential benefit outweighs the risk. Metoclopramide is excreted in breast milk, so caution is advised for nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoclopramide differs from serotonin‑type antiemetics such as ondansetron by targeting dopamine receptors and providing pro‑kinetic activity. It is useful when delayed gastric emptying contributes to symptoms, whereas ondansetron primarily blocks serotonin receptors without affecting motility.

Store the product at room temperature, below 25 °C, in its original container. Protect it from moisture and direct sunlight. Keep the packaging tightly closed and out of reach of children.

Metoclopramida Ipca is taken orally. Swallow the tablet whole with a glass of water; it may be taken with or without food, unless the prescriber advises otherwise.

Serious adverse reactions include extrapyramidal symptoms such as dystonia, tardive dyskinesia which can be irreversible, and neuroleptic malignant syndrome—a rare but life‑threatening condition characterized by fever, muscle rigidity and autonomic instability.

Metoclopramida should be avoided in patients with known hypersensitivity to metoclopramide, those with pheochromocytoma, seizure disorders, or a history of severe extrapyramidal reactions. Caution is also advised for individuals with gastrointestinal obstruction or perforation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Metoclopramide Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT