Product image of Metocor (Metoprolol) supplied by GNH India

Metocor

Active Ingredient:
Metoprolol
Origin:
EU

Metocor (Metoprolol)

Metoprolol, the active ingredient in Metocor, is a beta blocker presented as a tablet for oral use. It treats hypertension, angina pectoris, post‑myocardial infarction, chronic heart failure and cardiac arrhythmias in adult patients.

GNH India supplies Metocor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Rowex Ltd

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Indications & Clinical Uses

  • Metoprolol is a selective β1‑adrenergic antagonist used in several cardiovascular conditions.
  • Hypertension: lowers blood pressure and reduces cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand and relieves chest pain.
  • Post‑myocardial infarction: improves survival and prevents recurrent events.
  • Chronic heart failure: enhances left‑ventricular function and reduces hospitalisation.
  • Cardiac arrhythmias: controls heart rate in atrial fibrillation and other rhythm disorders.

How It Works

  • Metoprolol selectively blocks β1‑adrenergic receptors in cardiac tissue, inhibiting the effects of endogenous catecholamines. This reduces heart rate, myocardial contractility, and cardiac output, leading to decreased oxygen demand and lower systemic blood pressure. The drug’s action is dose‑dependent and primarily affects the heart without significant β2‑receptor activity in the lungs or vasculature.

Side Effects

Metoprolol may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Sleep disturbances or vivid dreams

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm in patients with reactive airway disease
  • Exacerbation of heart failure
  • Allergic reactions (rash, angioedema)
  • Cardiogenic shock in rare cases

Precautions & Warnings

  • Before prescribing Metocor, clinicians should consider several safety aspects.
  • Cardiovascular assessment: evaluate heart rate and blood pressure prior to initiation.
  • Respiratory conditions: use cautiously in patients with asthma or COPD.
  • Diabetes monitoring: beta‑blockade may mask hypoglycaemic symptoms.
  • Renal/hepatic impairment: dose adjustment may be required in reduced function.
  • Discontinuation: taper gradually to avoid rebound hypertension or tachycardia.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metocor can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Non‑selective beta blockers: additive bradycardia.
  • Calcium channel blockers (verapamil, diltiazem): increased risk of AV block.
  • Clonidine: abrupt withdrawal may precipitate severe hypertension.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypotensive effect.
  • Diuretics: increase risk of electrolyte imbalance and dehydration.
  • Antidiabetic agents: may mask signs of hypoglycaemia, requiring glucose monitoring.

Frequently Asked Questions

Metocor contains metoprolol, a selective β1‑blocker indicated for hypertension, angina pectoris, post‑myocardial infarction care, chronic heart failure, and certain cardiac arrhythmias such as atrial fibrillation. It helps control blood pressure, reduce chest pain, improve heart‑failure outcomes, and stabilise abnormal heart rhythms.

Metoprolol blocks β1‑adrenergic receptors in the heart, diminishing the effects of adrenaline and noradrenaline. This leads to a slower heart rate, reduced contractile force, and lower cardiac output, which together lower blood pressure and myocardial oxygen demand, providing therapeutic benefit in cardiovascular disease.

The specific dose of Metocor is determined by the prescribing clinician based on the patient’s condition, age, renal function, and response to therapy. Dosage regimens vary widely, and the prescriber will tailor the amount and frequency to achieve optimal clinical outcomes.

Safety data for metoprolol in pregnancy are limited, and the drug is generally classified as use‑only if the potential benefit justifies the risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should discuss risks and alternatives with their healthcare provider.

To place an order, submit an enquiry on the Metocor product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metocor (metoprolol) is a cardio‑selective β1‑blocker, offering a lower risk of bronchospasm compared with non‑selective agents like propranolol. Its pharmacokinetic profile provides once‑ or twice‑daily dosing, and it is widely used for heart‑failure management, whereas some alternatives may be preferred for migraine prophylaxis or tremor control.

Metocor tablets should be stored at temperatures below 25 °C, in a dry place, and kept in the original container to protect from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Metocor is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a full glass of water. The dosing schedule (once or twice daily) depends on the clinical indication and individual patient response.

Serious adverse events include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and worsening heart failure. Patients should be monitored for signs of these conditions, especially during dose initiation or adjustment.

Metocor is contraindicated in patients with known hypersensitivity to metoprolol or other beta‑blockers, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, cardiogenic shock, and uncontrolled severe asthma or COPD. Clinicians should assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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