Product image of Metocor (Metoprolol Tartrate) supplied by GNH India

Metocor

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metocor (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metocor, is a beta blocker presented as an oral tablet for systemic use. It lowers blood pressure, relieves angina, and helps manage heart rhythm disorders and post‑myocardial infarction care in adult patients. It is commonly prescribed for patients requiring cardiovascular risk reduction.

GNH India supplies Metocor as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide with adherence to quality standards, regulatory requirements and reliable logistics for global distribution.

Manufacturer / TM Owner

Rowex Ltd

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Indications & Clinical Uses

  • Metocor (metoprolol tartrate) is a selective β1‑adrenergic blocker used in cardiovascular disease management.
  • Hypertension: reduces systolic and diastolic blood pressure, decreasing cardiovascular strain.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest‑pain episodes.
  • Myocardial infarction: improves survival by lowering cardiac workload and preventing recurrent ischemic events.
  • Heart failure: lowers heart rate and improves ventricular filling, aiding symptom control.

How It Works

  • Metoprolol tartrate selectively antagonizes β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This reduces heart rate, myocardial contractility, and conduction velocity, leading to decreased cardiac output and lower arterial pressure. The drug also diminishes renin release from the kidneys, contributing to its antihypertensive effect.

Side Effects

Metocor may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Sleep disturbances or vivid dreams

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm in patients with reactive airway disease
  • Acute heart failure exacerbation
  • Allergic reactions (rash, angioedema, anaphylaxis)
  • Depression or mood changes

Precautions & Warnings

  • Before initiating Metocor, clinicians should consider several safety measures.
  • Monitor blood pressure and heart rate regularly: adjust dose if values fall outside therapeutic range.
  • Assess renal and hepatic function: dose reduction may be needed in impairment.
  • Caution in patients with asthma or chronic obstructive pulmonary disease: β1‑selectivity may not fully prevent bronchoconstriction.
  • Avoid abrupt discontinuation: taper dose to prevent rebound tachycardia or hypertension.
  • Use with caution in diabetic patients: may mask hypoglycaemia symptoms.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Metocor can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Verapamil or diltiazem: additive negative‑chronotropic effect may cause severe bradycardia.
  • Amiodarone: increases plasma metoprolol levels, raising risk of hypotension.
  • Clonidine withdrawal: abrupt cessation while on metoprolol can precipitate hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Calcium‑channel blockers (non‑dihydropyridine): may require dose adjustment.
  • NSAIDs: can blunt antihypertensive response.
  • Antidiabetic agents (insulin, sulfonylureas): monitor glucose as beta‑blockade may mask hypoglycaemia.
  • CYP2D6 inhibitors (e.g., fluoxetine, quinidine): may raise metoprolol concentrations.

Frequently Asked Questions

Metocor contains metoprolol tartrate, a beta‑blocker indicated for hypertension, angina pectoris, post‑myocardial infarction care, chronic heart failure, and certain cardiac arrhythmias. It is prescribed to reduce cardiovascular risk and improve symptom control in these conditions.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, decreasing the effects of adrenaline and noradrenaline. This leads to a slower heart rate, reduced contractility, lower cardiac output, and diminished renin release, collectively lowering blood pressure and cardiac workload.

The appropriate dose of Metocor is determined by the prescribing clinician based on the patient’s medical condition, response to therapy, and any comorbidities. Dosage may be started low and titrated upward, but exact regimens should follow the prescriber’s instructions.

The safety of metoprolol tartrate in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the Metocor product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Metocor (metoprolol tartrate) is a cardio‑selective β1‑blocker, offering a favorable profile for patients with respiratory disease compared with non‑selective agents. Its relatively short half‑life allows flexible dosing, while other beta‑blockers such as atenolol have longer durations but may differ in renal clearance and side‑effect patterns.

Metocor should be stored at room temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, direct sunlight, and excessive heat to maintain potency throughout its shelf life.

Metocor is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically advised.

Serious adverse events can include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience fainting, severe dizziness, difficulty breathing, or swelling of the face or throat.

Metocor is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, in those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, cardiogenic shock, or overt heart failure decompensation. Caution is also advised for individuals with uncontrolled asthma or severe peripheral vascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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