Product image of Metomylan (Metoprolol Tartrate) supplied by GNH India

Metomylan

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metomylan (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metomylan, is a beta blocker presented as an oral dosage form for oral use. It treats hypertension, angina, myocardial infarction, heart failure, and cardiac arrhythmias in adult patients.

GNH India supplies Metomylan as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

Metoprolol Tartrate is used to manage cardiovascular conditions that involve elevated heart rate or excessive cardiac workload.

  • Hypertension: lowers blood pressure by reducing heart rate and cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Myocardial infarction: improves survival after a heart attack by limiting further cardiac stress.
  • Heart failure: reduces ventricular workload and improves symptoms.
  • Cardiac arrhythmias: controls abnormal heart rhythms by slowing conduction through the AV node.

How It Works

  • Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, inhibiting the effects of endogenous catecholamines. This antagonism reduces heart rate, myocardial contractility, and cardiac output, leading to lower arterial pressure and decreased myocardial oxygen consumption, which underlies its therapeutic benefits in cardiovascular disease.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities or reduced peripheral circulation
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Depression or mood changes

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in patients with asthma or COPD
  • Acute heart failure exacerbation
  • Allergic reactions (rash, angioedema, anaphylaxis)
  • Cardiogenic shock

Precautions & Warnings

Before initiating Metoprolol Tartrate, clinicians should evaluate patient-specific factors and monitor therapy closely.

  • Cardiac assessment: verify baseline heart rate and blood pressure.
  • Respiratory caution: avoid in uncontrolled asthma or severe COPD.
  • Renal/hepatic function: adjust dose in impairment.
  • Concomitant drugs: review other beta‑blockers or calcium‑channel blockers.
  • Pregnancy: category C; weigh maternal benefits against fetal risks.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metoprolol Tartrate can interact with several medication classes; awareness of interaction severity guides clinical decisions.

Major Interactions (Avoid)

  • Other beta‑blockers: additive cardiac depression.
  • Non‑dihydropyridine calcium‑channel blockers (verapamil, diltiazem): risk of severe bradycardia and AV block.
  • Class I antiarrhythmics (e.g., quinidine): enhanced negative chronotropic effect.
  • MAO inhibitors: possible hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive effect.
  • Diuretics: increase risk of hypotension.
  • Antidiabetic agents: may mask hypoglycemia symptoms.
  • Antidepressants (SSRIs, SNRIs): potential for additive bradycardia.
  • Anesthetic agents: may potentiate cardiovascular depression.

Frequently Asked Questions

Metomylan contains metoprolol tartrate, a beta‑blocker indicated for hypertension, angina pectoris, post‑myocardial infarction care, chronic heart failure, and certain cardiac arrhythmias. It works by lowering heart rate and reducing the heart’s workload, helping to control blood pressure and relieve chest pain.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in cardiac tissue. By inhibiting the action of adrenaline and noradrenaline at these sites, it decreases heart rate, myocardial contractility, and cardiac output, which together lower arterial pressure and reduce oxygen demand of the heart muscle.

The appropriate dose of Metomylan is determined by the prescribing healthcare professional based on the patient’s specific condition, response to therapy, and any comorbidities. Dosage may be adjusted over time to achieve optimal blood pressure or symptom control.

Metomylan is classified as pregnancy category C, meaning risk cannot be ruled out. It should only be used if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their physician, as metoprolol can be excreted in breast milk.

To place an order, submit an enquiry on the Metomylan product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metomylan (metoprolol tartrate) is a cardio‑selective β1‑blocker, offering a favorable profile for patients with respiratory conditions compared with non‑selective agents like propranolol. Its once‑ or twice‑daily dosing and proven efficacy in heart failure make it a common choice, though individual response and tolerability guide final selection.

Metomylan should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and potency throughout its shelf life.

Metomylan is taken orally, usually with or without food, as directed by the prescribing clinician. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with asthma or COPD, and worsening heart failure. Patients should be monitored for signs of these conditions, especially during dose initiation or escalation.

Metomylan is contraindicated in patients with known hypersensitivity to metoprolol or any excipients, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, cardiogenic shock, and uncontrolled asthma or severe COPD. Clinicians must assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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