Product image of Metoprolol Alvogen (Metoprolol Tartrate) supplied by GNH India

Metoprolol Alvogen

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Alvogen (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Alvogen, is a beta blocker presented as an oral tablet for oral use. It lowers blood pressure and heart rate, and is used to manage hypertension, angina pectoris, heart failure, and post‑myocardial infarction in adult patients.

GNH India supplies Metoprolol Alvogen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, ensuring timely delivery and regulatory compliance.

Manufacturer / TM Owner

Alvogen Ehf

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Indications & Clinical Uses

Metoprolol Alvogen, a selective β1‑adrenergic blocker, is employed in cardiovascular conditions where reduction of cardiac workload is desired.

  • Hypertension: reduces systolic and diastolic pressure, decreasing risk of stroke and organ damage.
  • Angina pectoris: lowers myocardial oxygen demand, relieving chest‑pain episodes.
  • Heart failure: improves ventricular function and reduces hospitalization rates.
  • Post‑myocardial infarction: decreases mortality and recurrent ischemic events.

How It Works

  • Metoprolol Tartrate selectively antagonizes β1‑adrenergic receptors primarily located in cardiac tissue. By blocking catecholamine binding, it diminishes cyclic AMP formation, leading to reduced heart rate (negative chronotropy), decreased myocardial contractility (negative inotropy), and lowered conduction velocity (negative dromotropy). The overall effect is a reduction in cardiac output and arterial pressure without significant β2‑mediated bronchial effects.

Side Effects

Metoprolol Alvogen may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Fatigue
  • Dizziness
  • Cold extremities
  • Bradycardia
  • Gastrointestinal upset
  • Sleep disturbances

Serious or Rare Side Effects

  • Severe bradycardia
  • Heart block
  • Marked hypotension
  • Bronchospasm in asthmatic patients
  • Depression
  • Allergic reactions such as rash or angioedema

Precautions & Warnings

When prescribing Metoprolol Alvogen, clinicians should consider several safety measures.

  • Monitor blood pressure: adjust dose based on response.
  • Assess heart rate: watch for excessive bradycardia.
  • Evaluate cardiac function: use caution in decompensated heart failure.
  • Review respiratory status: avoid in uncontrolled asthma or COPD.
  • Consider renal/hepatic impairment: dose may need adjustment.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metoprolol Alvogen can interact with other medicines; awareness of the interaction level guides clinical decisions.

Major Interactions (Avoid)

  • Concomitant use with non‑selective beta blockers: additive bradycardia.
  • Combined with calcium‑channel blockers (verapamil, diltiazem): risk of severe AV block.
  • Concurrent MAO inhibitors: enhanced hypotensive effect.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may reduce antihypertensive efficacy.
  • Antidiabetic agents: may mask hypoglycemia symptoms.
  • SSRIs and other antidepressants: potential for increased bradycardia.
  • Digoxin: may raise serum digoxin concentrations.

Frequently Asked Questions

Metoprolol Alvogen contains metoprolol tartrate, a beta‑blocker indicated for the management of hypertension, angina pectoris, chronic heart failure, and for reducing the risk of recurrent events after a myocardial infarction. It works by decreasing the heart's workload and lowering blood pressure.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, preventing catecholamines from stimulating these receptors. This leads to a slower heart rate, reduced contractile force, and lower cardiac output, which together help to lower arterial pressure and myocardial oxygen demand.

The appropriate dose of Metoprolol Alvogen is individualized by the prescribing clinician based on the patient’s specific condition, response to therapy, age, renal and hepatic function, and any concomitant medications. No fixed regimen is provided here.

The pregnancy safety category for metoprolol tartrate is not definitively established. It should only be used during pregnancy or lactation if the potential benefits outweigh the risks, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Metoprolol is a cardio‑selective beta‑blocker, offering heart‑rate control and reduced myocardial oxygen demand, which differs from ACE inhibitors, calcium‑channel blockers, or diuretics that act on the renin‑angiotensin system, vascular smooth muscle, or fluid balance respectively. Choice depends on patient comorbidities, tolerability and therapeutic goals.

Metoprolol Alvogen tablets should be stored below 25 °C, in the original container, protected from moisture and direct light. Do not store in bathrooms or near heat sources to maintain product stability.

Metoprolol Alvogen is taken orally as a tablet, usually with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed by a healthcare provider.

Serious adverse events include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with asthma or COPD, and rare allergic reactions such as angioedema. Patients should seek immediate medical attention if they experience fainting, chest pain, severe shortness of breath, or swelling of the face or throat.

Metoprolol Alvogen is contraindicated in patients with known hypersensitivity to metoprolol or other beta‑blockers, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and individuals with uncompensated heart failure or severe peripheral vascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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