Product image of Metoprolol Aurobindo (Metoprolol Tartrate) supplied by GNH India

Metoprolol Aurobindo

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Aurobindo (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Aurobindo, is a beta blocker presented as oral tablets for oral use. It is used to lower high blood pressure, relieve chest pain from angina, and improve outcomes after heart attacks and in chronic heart failure. It is indicated for adults and is prescribed by physicians based on individual clinical assessment.

GNH India supplies Metoprolol Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory‑approved batches for global distribution.

Manufacturer / TM Owner

Aurobindo Pharma (Malta) Limited

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Indications & Clinical Uses

Metoprolol Aurobindo is used in cardiovascular conditions where β1‑adrenergic blockade improves outcomes.

  • Hypertension: reduces systolic and diastolic blood pressure, helping patients reach target levels.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain during exertion.
  • Myocardial infarction: lowers the risk of recurrent ischemic events and improves survival after an acute heart attack.
  • Heart failure: diminishes heart rate and contractility, supporting ventricular function and reducing hospitalizations.

How It Works

  • Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in cardiac tissue, inhibiting the effects of endogenous catecholamines. This antagonism reduces heart rate, myocardial contractility, and consequently cardiac output, leading to lower blood pressure and decreased myocardial oxygen consumption.

Side Effects

Metoprolol Aurobindo may cause a range of adverse reactions.

Common Side Effects

  • Fatigue or tiredness.
  • Dizziness, especially when standing quickly.
  • Cold extremities such as hands and feet.
  • Gastrointestinal discomfort, including nausea or abdominal pain.
  • Mild depression or mood changes.

Serious or Rare Side Effects

  • Severe bradycardia (abnormally low heart rate).
  • Hypotension leading to fainting or shock.
  • Heart block or worsening heart failure.
  • Bronchospasm in patients with asthma or COPD.
  • Allergic reactions such as rash, itching, or swelling.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Cardiovascular assessment: evaluate heart rate, blood pressure, and cardiac function.
  • Concomitant beta‑blocker use: avoid duplicate therapy to prevent excessive β‑blockade.
  • Respiratory disease: use cautiously in patients with asthma or chronic obstructive pulmonary disease.
  • Diabetes: monitor blood glucose as beta‑blockade may mask hypoglycaemia symptoms.
  • Pregnancy and lactation: safety not established; weigh potential benefits against risks.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metoprolol Aurobindo can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: additive cardiac depression.
  • Calcium channel blockers (e.g., verapamil, diltiazem): may cause severe bradycardia or heart block.
  • Antihypertensive agents (e.g., ACE inhibitors, diuretics): risk of profound hypotension.

Moderate Interactions (Monitor Closely)

  • Antidiabetic drugs: beta‑blockade can mask hypoglycaemia signs.
  • Antidepressants (e.g., SSRIs, tricyclics): may increase plasma metoprolol levels.
  • NSAIDs: can reduce antihypertensive efficacy.
  • CYP2D6 inhibitors (e.g., quinidine, fluoxetine): may raise metoprolol concentrations.

Frequently Asked Questions

Metoprolol Aurobindo is prescribed for high blood pressure (hypertension), chest pain due to angina pectoris, management after a myocardial infarction, and chronic heart failure. It works by slowing the heart and reducing the force of contraction, which helps lower blood pressure and cardiac workload.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart. By inhibiting the action of adrenaline and noradrenaline at these sites, it reduces heart rate, myocardial contractility, and cardiac output, leading to lower blood pressure and decreased oxygen demand by the heart muscle.

The dosage of Metoprolol Aurobindo is individualized. A qualified prescriber determines the appropriate strength, frequency, and duration based on the patient’s specific condition, response to therapy, and any co‑existing medical issues.

Safety data for Metoprolol Tartrate in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. Its pharmacokinetic profile provides once‑ or twice‑daily dosing options, making it convenient for many patients while still delivering effective blood‑pressure and heart‑rate control.

Store Metoprolol Aurobindo tablets at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Metoprolol Aurobindo is taken orally, usually with or without food, as directed by the prescribing physician. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious adverse events can include severe bradycardia, marked hypotension, heart block, worsening heart failure, and bronchospasm in patients with underlying respiratory disease. Patients should seek immediate medical attention if they experience fainting, very slow heart rate, difficulty breathing, or sudden swelling.

Metoprolol Aurobindo is contraindicated in individuals with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and patients in cardiogenic shock. It should also be used with caution in severe asthma or COPD.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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