Product image of Metoprolol Aurovitas (Metoprolol Tartrate) supplied by GNH India

Metoprolol Aurovitas

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Aurovitas (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Aurovitas, is a beta‑adrenergic blocker presented as an oral tablet for systemic use. It is employed to lower elevated blood pressure, relieve angina pectoris, improve outcomes after myocardial infarction, and manage chronic heart failure in adult patients and is commonly prescribed in cardiovascular therapy.

GNH India supplies Metoprolol Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

Metoprolol Aurovitas, a selective β1‑adrenergic blocker, is used in several cardiovascular conditions.

  • Hypertension: reduces systolic and diastolic blood pressure, helping patients reach target levels.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain during exertion.
  • Post‑myocardial infarction: lowers the risk of recurrent ischemic events and improves survival.
  • Chronic heart failure: improves ventricular function and reduces hospitalisation rates.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation of adenylate cyclase. This reduces intracellular cyclic AMP, leading to decreased heart rate, contractility, and cardiac output, while also lowering renin release from the kidneys, contributing to its antihypertensive effect.

Side Effects

Metoprolol Aurovitas may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Fatigue: feeling unusually tired or weak.
  • Dizziness or light‑headedness, especially when standing quickly.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced blood flow to hands and feet.

Serious or Rare Side Effects

  • Severe bradycardia or heart block requiring medical attention.
  • Marked hypotension leading to fainting or shock.
  • Bronchospasm or worsening asthma symptoms.
  • Allergic reactions such as rash, swelling, or anaphylaxis.
  • Hepatic dysfunction or jaundice.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Monitor blood pressure: check regularly to avoid excessive hypotension.
  • Assess heart rate: watch for bradycardia, especially in patients with conduction disorders.
  • Review respiratory status: use cautiously in patients with asthma or chronic obstructive pulmonary disease.
  • Evaluate renal and hepatic function: dose adjustments may be needed in impairment.
  • Pregnancy and lactation: prescribe only if benefits outweigh potential risks.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Metoprolol Aurovitas can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Non‑selective beta blockers: additive bradycardia and AV‑block risk.
  • Calcium‑channel blockers (verapamil, diltiazem): may cause severe conduction disturbances.
  • Clonidine abrupt withdrawal: can precipitate rebound hypertension.
  • Insulin or oral hypoglycemics: may mask hypoglycaemia symptoms.

Moderate Interactions (Monitor Closely)

  • Diuretics: enhanced hypotensive effect, monitor electrolytes.
  • ACE inhibitors or ARBs: additive blood‑pressure lowering, watch for renal function changes.
  • NSAIDs: may reduce antihypertensive efficacy, observe blood‑pressure trends.

Frequently Asked Questions

Metoprolol Aurovitas is prescribed to treat high blood pressure, relieve angina pectoris, improve outcomes after a heart attack, and manage chronic heart failure. It works by slowing the heart and reducing the force of contraction, which helps lower the workload on the cardiovascular system.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, decreasing the response to adrenaline and noradrenaline. This leads to a slower heart rate, reduced contractile strength, and lower cardiac output, while also diminishing renin release from the kidneys, contributing to blood‑pressure reduction.

The appropriate dose of Metoprolol Aurovitas is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the dosage instructions provided by their healthcare professional and not adjust the dose on their own.

Safety data for Metoprolol Aurovitas in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternatives with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metoprolol is a cardio‑selective (β1‑specific) blocker, which generally causes fewer respiratory side effects than non‑selective beta‑blockers. Compared with agents like atenolol, it has a shorter half‑life and may require twice‑daily dosing, but it offers similar efficacy for hypertension, angina, and heart‑failure management.

Metoprolol Aurovitas should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency throughout its shelf life.

Metoprolol Aurovitas is taken orally, usually with or without food, as directed by a healthcare professional. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with asthma or COPD, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience fainting, severe shortness of breath, or signs of an allergic response.

Metoprolol Aurovitas is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, and individuals in cardiogenic shock. Clinicians should also exercise caution in patients with uncontrolled asthma or severe peripheral vascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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