Product image of Metoprolol Aurovitas (Metoprolol Tartrate) supplied by GNH India

Metoprolol Aurovitas

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Aurovitas (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Aurovitas, is a beta blocker presented as an oral tablet for oral use. It lowers blood pressure and reduces cardiac workload in adults with hypertension, angina, or certain heart rhythm disorders.

GNH India supplies Metoprolol Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution. Customers benefit from consistent product availability and regulatory compliance.

Manufacturer / TM Owner

Aurovitas Spain,s.A.U.

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Indications & Clinical Uses

Metoprolol Aurovitas is a beta‑adrenergic blocker indicated for several cardiovascular conditions.

  • Hypertension: helps control elevated blood pressure.
  • Angina pectoris: reduces frequency of chest pain episodes.
  • Myocardial infarction: lowers risk of recurrent cardiac events.
  • Heart failure: improves ventricular function and symptoms.
  • Cardiac arrhythmias: stabilises abnormal heart rhythms.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, decreasing sympathetic stimulation. This results in reduced heart rate, myocardial contractility, and cardiac output, which together lower systemic blood pressure and diminish myocardial oxygen demand, providing therapeutic benefit in hypertension, angina, and arrhythmic conditions.

Side Effects

Metoprolol Aurovitas may cause a range of adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects

  • Fatigue: feeling of tiredness or lack of energy.
  • Dizziness: light‑headed sensation, especially on standing.
  • Cold extremities: reduced peripheral circulation.
  • Gastrointestinal upset: nausea or abdominal discomfort.
  • Sleep disturbances: insomnia or vivid dreams.
  • Bradycardia: slower than normal heart rate.

Serious or Rare Side Effects

  • Severe bradycardia: markedly low heart rate requiring medical attention.
  • Heart block: impairment of electrical conduction.
  • Hypotension: dangerously low blood pressure.
  • Bronchospasm: narrowing of airways, especially in asthmatic patients.
  • Depression: mood changes or depressive symptoms.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.

Precautions & Warnings

When prescribing Metoprolol Aurovitas, clinicians should observe several precautionary measures to ensure patient safety.

  • Assess cardiac function: evaluate heart rate and blood pressure before initiation.
  • Monitor for bronchospasm: avoid in patients with active asthma or COPD.
  • Adjust in renal/hepatic impairment: dose may need modification based on organ function.
  • Avoid abrupt discontinuation: taper gradually to prevent rebound hypertension.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture.

Avoid Interactions

Metoprolol Aurovitas can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: concurrent use may cause excessive β‑blockade.
  • Calcium channel blockers (verapamil, diltiazem): increase risk of bradycardia and AV block.
  • Clonidine: abrupt withdrawal may precipitate hypertensive crisis.
  • Insulin or oral hypoglycemics: may mask hypoglycemia symptoms.
  • Potassium‑sparing diuretics: may enhance hyperkalemia.

Moderate Interactions (Monitor Closely)

  • Other antihypertensives: additive blood pressure lowering.
  • Antidepressants (SSRIs, SNRIs): may affect heart rate.
  • NSAIDs: may reduce antihypertensive effect.
  • CYP2D6 inhibitors (e.g., fluoxetine): increase metoprolol plasma levels.
  • Thyroid hormones: may alter heart rate response.

Frequently Asked Questions

Metoprolol Aurovitas is a prescription beta‑blocker indicated for the treatment of hypertension, chronic stable angina, post‑myocardial infarction management, heart failure with reduced ejection fraction, and certain cardiac arrhythmias. It works by moderating heart rate and contractility, thereby lowering blood pressure and myocardial oxygen demand.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, reducing the effects of sympathetic stimulation. This leads to a slower heart rate, decreased contractile force, and lower cardiac output, which together help to lower systemic blood pressure and lessen the heart's oxygen requirements.

The appropriate dose of Metoprolol Aurovitas is determined by a qualified healthcare professional based on the individual’s medical condition, response to therapy, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for Metoprolol Aurovitas in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the Metoprolol Aurovitas product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) beta‑blocker, offering a favorable profile for patients with respiratory conditions compared with non‑selective agents like propranolol. Its relatively short half‑life allows flexible dosing, while agents such as atenolol have longer half‑lives. Choice of agent depends on individual patient characteristics, comorbidities, and physician preference.

Metoprolol Aurovitas tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or direct sunlight.

Metoprolol Aurovitas is taken orally, usually as a whole tablet swallowed with a glass of water. It can be taken with or without food, but consistency with respect to meals is recommended to maintain stable plasma levels. Patients should follow the dosing schedule prescribed by their clinician.

Serious adverse events include marked bradycardia, symptomatic hypotension, atrioventricular block, bronchospasm in susceptible individuals, and severe depression. Patients should seek immediate medical attention if they experience fainting, severe shortness of breath, chest pain, or any signs of an allergic reaction such as swelling or difficulty breathing.

Metoprolol Aurovitas is contraindicated in patients with severe bradycardia (heart rate < 45 bpm), second‑ or third‑degree AV block without a pacemaker, cardiogenic shock, decompensated heart failure, and uncontrolled asthma or severe chronic obstructive pulmonary disease. It should also be avoided in individuals with known hypersensitivity to metoprolol or any excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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