Product image of Metoprolol Eg (Metoprolol Tartrate) supplied by GNH India

Metoprolol Eg

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Eg (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Eg, is a beta‑adrenergic blocker presented as an oral dosage form for oral use. It lowers elevated blood pressure, relieves angina, and improves outcomes after myocardial infarction and in chronic heart failure, acting primarily in adult patients with cardiovascular disease.

GNH India supplies Metoprolol Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

  • Metoprolol Eg is a beta‑blocker indicated for several cardiovascular conditions.
  • Hypertension: reduces systolic and diastolic blood pressure, decreasing the risk of stroke and heart attack.
  • Angina pectoris: lowers myocardial oxygen demand, relieving chest pain during exertion.
  • Myocardial infarction: improves survival and reduces recurrent ischemic events after an acute heart attack.
  • Heart failure: decreases mortality and hospitalisation by reducing cardiac workload and neuro‑hormonal activation.
  • Cardiac arrhythmias: controls ventricular rate in atrial fibrillation and other tachyarrhythmias.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, leading to a reduction in heart rate, myocardial contractility, and cardiac output. By blunting sympathetic stimulation, it lowers systemic vascular resistance and blood pressure, thereby decreasing myocardial oxygen consumption and stabilising cardiac rhythm.

Side Effects

Metoprolol Eg may cause a range of adverse reactions, which are grouped by frequency.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Headache

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in patients with asthma or COPD
  • Allergic reactions (rash, angioedema)
  • Depression or mood changes

Precautions & Warnings

  • Before prescribing Metoprolol Eg, clinicians should evaluate patient‑specific factors and monitor for potential risks.
  • Assess cardiovascular status: check baseline heart rate and blood pressure.
  • Monitor for bronchospastic disease: use cautiously in asthma or chronic obstructive pulmonary disease.
  • Adjust in renal/hepatic impairment: dose may need modification in reduced organ function.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent rebound tachycardia.
  • Pregnancy and lactation: risk unknown; weigh benefits against potential fetal or infant exposure.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Metoprolol Eg can interact with several medicines; some combinations should be avoided while others require close monitoring.

Major Interactions (Avoid)

  • Non‑selective beta blockers (e.g., propranolol): additive bradycardia.
  • Calcium‑channel blockers verapamil or diltiazem: risk of severe atrioventricular block.
  • Clonidine: may cause rebound hypertension on abrupt withdrawal.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., thiazides): may enhance hypotensive effect.
  • NSAIDs: may reduce the antihypertensive efficacy of metoprolol.

Frequently Asked Questions

Metoprolol Eg is prescribed for high blood pressure (hypertension), chest pain due to angina pectoris, management after a myocardial infarction, chronic heart failure, and certain cardiac arrhythmias such as atrial fibrillation. It works by reducing the heart's workload and stabilising heart rhythm, helping to prevent complications associated with these cardiovascular disorders.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors located mainly in the heart. This inhibition reduces the effects of adrenaline and noradrenaline, leading to a slower heart rate, decreased contractile force, and lower cardiac output. The resulting drop in blood pressure and myocardial oxygen demand underlies its therapeutic benefits in hypertension, angina, and heart failure.

The dose of Metoprolol Eg is individualized and determined by the prescribing clinician based on the specific indication, patient age, renal function, and response to therapy. Dosage may start low and be titrated upward to achieve target blood pressure or heart‑rate goals while monitoring for side effects. Patients should follow the exact regimen provided by their healthcare professional.

The safety of Metoprolol Tartrate in pregnancy and lactation has not been definitively established, and the product’s pregnancy category is listed as unknown. Clinicians must weigh the potential benefits against possible risks to the fetus or infant. If treatment is considered essential, it should be prescribed by a specialist familiar with maternal‑fetal medicine.

To request Metoprolol Eg, visit the product page on gnhindia.com and submit an enquiry specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing a formal quotation, availability, shipping details, and any necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) beta‑blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. It is commonly used for hypertension, angina, and heart failure, whereas some alternatives may be preferred for migraine prophylaxis or tremor control. Choice of agent depends on the patient’s comorbidities, tolerance, and therapeutic goals.

Metoprolol Eg should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Do not store in areas of high humidity or near heat sources. Keep the product out of reach of children and discard any tablets that appear discoloured or damaged.

Metoprolol Eg is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the prescriber’s instructions regarding timing relative to meals. Tablets should be swallowed whole and not crushed or chewed unless a specific formulation allows it.

Serious adverse events include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and rare allergic reactions such as angioedema. Patients should seek immediate medical attention if they experience fainting, extreme fatigue, difficulty breathing, or signs of an allergic response.

Metoprolol Eg is contraindicated in patients with known hypersensitivity to metoprolol or any excipients, those with severe bradycardia (heart rate < 45 bpm), second‑ or third‑degree atrioventricular block without a pacemaker, and individuals in cardiogenic shock. Caution is also advised for patients with uncontrolled asthma, severe peripheral vascular disease, or decompensated heart failure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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