Product image of Metoprolol Egis (Metoprolol Tartrate) supplied by GNH India

Metoprolol Egis

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Egis (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Egis, is a beta blocker presented as an oral tablet for oral use. It is used to manage high blood pressure, chest pain, and certain heart‑failure conditions in adult patients.
GNH India supplies Metoprolol Egis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Egis Pharmaceuticals Plc

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Indications & Clinical Uses

Metoprolol Egis is a selective β1‑adrenergic blocker indicated for several cardiovascular conditions.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain episodes.
  • Post‑myocardial infarction: improves survival by reducing arrhythmic events and cardiac workload.
  • Chronic heart failure: enhances ventricular function and reduces hospitalisations.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑mediated stimulation. This results in a slower heart rate, reduced myocardial contractility, and lower cardiac output, thereby decreasing blood pressure and myocardial oxygen consumption.

Side Effects

Metoprolol Egis may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Cold extremities (hands and feet)
  • Gastrointestinal upset (nausea, abdominal discomfort)

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in patients with asthma or COPD
  • Allergic reactions such as rash, angioedema, or anaphylaxis

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor for adverse events.

  • Blood pressure monitoring: ensure adequate control without excessive hypotension.
  • Cardiac function assessment: use caution in patients with existing heart block or severe heart failure.
  • Respiratory caution: avoid in uncontrolled asthma or severe chronic obstructive pulmonary disease.
  • Renal/hepatic impairment: dose adjustments may be required in reduced clearance.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Metoprolol Egis can interact with several drug classes, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Combined use with other AV‑node blockers (e.g., verapamil, diltiazem) may cause profound bradycardia.
  • Abrupt discontinuation of clonidine while on Metoprolol can precipitate hypertensive crisis.
  • Concurrent insulin or oral hypoglycemics may mask hypoglycaemia symptoms.
  • NSAIDs may diminish antihypertensive effect, leading to uncontrolled blood pressure.

Moderate Interactions (Monitor Closely)

  • Calcium‑channel blockers (non‑dihydropyridines) may enhance negative chronotropic effects.
  • Diuretics can potentiate hypotensive response.
  • Certain antidepressants (e.g., SSRIs) may increase plasma concentrations of Metoprolol.

Frequently Asked Questions

Metoprolol Egis is prescribed for high blood pressure (hypertension), chest pain due to angina pectoris, post‑myocardial infarction management, and chronic heart failure. It works by reducing heart rate and cardiac workload, helping to control these cardiovascular disorders.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart. By inhibiting the effects of adrenaline and noradrenaline, it slows the heart rate, lowers myocardial contractility, and reduces cardiac output, which together lower blood pressure and oxygen demand.

The appropriate dose of Metoprolol Egis is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other medications. Patients should follow the dosage instructions provided by their healthcare professional.

Safety data for Metoprolol Egis in pregnancy and lactation are limited. The drug should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To request Metoprolol Egis, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metoprolol Egis is a cardio‑selective (β1‑selective) blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. Its pharmacokinetic profile provides once‑ or twice‑daily dosing options, making it convenient for many patients while maintaining effective blood pressure and heart‑rate control.

Metoprolol Egis should be stored at temperatures below 25 °C in its original container, protected from moisture and direct sunlight. Keeping the product in a dry, cool place helps maintain its stability and potency throughout its shelf life.

Metoprolol Egis is taken orally, usually with or without food, as directed by a healthcare professional. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience fainting, severe dizziness, difficulty breathing, or signs of an allergic response.

Metoprolol Egis is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and individuals in cardiogenic shock. Clinicians should also exercise caution in patients with uncontrolled asthma or severe chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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