Product image of Metoprolol Hexal (Metoprolol Succinate) supplied by GNH India

Metoprolol Hexal

Active Ingredient:
Metoprolol Succinate
Origin:
EU

Metoprolol Hexal (Metoprolol Succinate)

Metoprolol succinate, the active ingredient in Metoprolol Hexal, is a beta blocker presented as an oral tablet for oral use. It reduces heart rate and cardiac output, and is employed to manage hypertension, angina pectoris and chronic heart failure in adult patients.

GNH India supplies Metoprolol Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other health‑care institutions worldwide. The company adheres to stringent quality standards and provides regulatory support for cross‑border distribution, ensuring product integrity.

Manufacturer / TM Owner

Hexal Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metoprolol Hexal, a selective β1‑adrenergic blocker, is used in several cardiovascular conditions.

  • Hypertension: lowers blood pressure by decreasing cardiac output and inhibiting renin release.
  • Angina pectoris: reduces myocardial oxygen demand through heart‑rate and contractility control.
  • Chronic heart failure: improves survival and symptoms by decreasing ventricular workload.
  • Post‑myocardial infarction: lowers risk of recurrent ischemic events and arrhythmias.

How It Works

  • Metoprolol succinate selectively antagonizes β1‑adrenergic receptors in cardiac tissue, diminishing sympathetic stimulation. This leads to a reduction in heart rate, myocardial contractility, and conduction velocity, which together lower cardiac output and blood pressure, helping to control hypertension, angina, and heart‑failure progression.

Side Effects

Metoprolol Hexal may cause a range of adverse reactions.

Common Side Effects

  • Fatigue: feeling unusually tired or weak.
  • Dizziness: light‑headedness, especially when standing quickly.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced blood flow to hands and feet.
  • Gastrointestinal upset: nausea or abdominal discomfort.
  • Depression: low mood or loss of interest.

Serious or Rare Side Effects

  • Severe bradycardia or heart block requiring medical attention.
  • Marked hypotension leading to fainting.
  • Bronchospasm in patients with reactive airway disease.
  • Acute heart failure exacerbation.
  • Allergic reactions such as rash, itching, or swelling.
  • Cardiogenic shock in rare cases.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Monitor blood pressure: ensure adequate control without excessive lowering.
  • Assess heart rate: watch for bradycardia, especially in patients with conduction disorders.
  • Use caution in asthma or COPD: β1‑selectivity may still affect bronchial tone.
  • Avoid abrupt discontinuation: taper gradually to prevent rebound tachycardia or hypertension.
  • Adjust dose in renal impairment: reduced clearance may require lower dosing.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Metoprolol Hexal can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Verapamil or diltiazem: combined negative chronotropic effect may cause severe bradycardia.
  • Clonidine withdrawal: abrupt cessation while on metoprolol can precipitate hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypotensive effect; monitor blood pressure.
  • Diuretics: additive blood‑pressure lowering; watch for electrolyte disturbances.
  • NSAIDs: may reduce antihypertensive efficacy; assess renal function and blood pressure.

Frequently Asked Questions

Metoprolol Hexal contains metoprolol succinate, a selective β1‑adrenergic blocker indicated for the treatment of hypertension, angina pectoris, chronic heart failure, and for secondary prevention after myocardial infarction. It helps lower blood pressure, reduce chest‑pain episodes, and improve heart‑failure outcomes.

Metoprolol succinate blocks β1‑adrenergic receptors in the heart, decreasing the effects of sympathetic nervous system stimulation. This results in a slower heart rate, reduced contractility, and lower cardiac output, which together lower blood pressure and myocardial oxygen demand.

The appropriate dose of Metoprolol Hexal is individualized by the prescribing clinician based on the patient’s condition, response, and tolerability. Dosage may be adjusted over time, and patients should follow the prescriber’s instructions without self‑adjusting the amount.

Safety data for metoprolol succinate in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss risks with their healthcare provider.

To request Metoprolol Hexal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and import documentation.

Metoprolol succinate is a cardio‑selective β1‑blocker, offering a favorable profile for patients with hypertension, angina, or heart failure. Compared with non‑selective agents such as propranolol, metoprolol has less impact on bronchial β2 receptors, making it a safer option for patients with mild respiratory disease.

Metoprolol Hexal tablets should be stored at room temperature, below 25 °C, in the original container to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date printed on the packaging.

Metoprolol Hexal is taken orally, usually as a whole tablet swallowed with water. It may be taken with or without food, but patients should follow the prescriber’s guidance on timing and whether the dose should be taken once daily or in divided doses.

Serious adverse events can include severe bradycardia, heart block, marked hypotension, bronchospasm in susceptible individuals, and rare cases of cardiogenic shock. Patients should seek immediate medical attention if they experience fainting, extreme fatigue, difficulty breathing, or a rapid change in heart rhythm.

Metoprolol Hexal is contraindicated in patients with known hypersensitivity to metoprolol or other beta blockers, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and individuals in cardiogenic shock. Caution is also advised for patients with uncontrolled asthma or severe peripheral vascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.