Product image of Metoprolol Medical Valley (Metoprolol Tartrate) supplied by GNH India

Metoprolol Medical Valley

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Medical Valley (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Medical Valley, is a beta blocker presented as an oral tablet for oral use. It is employed to manage high blood pressure, relieve angina, improve outcomes after myocardial infarction, and treat certain cardiac rhythm disorders.

GNH India supplies Metoprolol Medical Valley as a licensed, GDP‑compliant international pharmaceutical supplier, originating from the European Union, and serves hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

Metoprolol Tartrate is a selective β1‑adrenergic antagonist used in cardiovascular disease management.

  • Hypertension: lowers systolic and diastolic pressure by reducing heart rate and cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Myocardial infarction: improves survival by limiting cardiac workload after an attack.
  • Heart failure: reduces ventricular remodeling and symptoms of reduced ejection fraction.
  • Cardiac arrhythmias: controls ventricular rate in atrial fibrillation and other rhythm disturbances.

How It Works

  • Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, inhibiting catecholamine binding. This antagonism reduces intracellular cyclic AMP, leading to decreased calcium influx, slower sinoatrial node firing, reduced myocardial contractility, and lower cardiac output, ultimately lowering blood pressure and heart rate.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions.

Common Side Effects

  • Fatigue: feeling unusually tired or weak.
  • Dizziness: light‑headedness, especially when standing quickly.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced blood flow to hands and feet.
  • Gastrointestinal upset: nausea or abdominal discomfort.

Serious or Rare Side Effects

  • Severe bradycardia: heart rate dropping to dangerously low levels.
  • Heart block: impaired electrical conduction requiring medical attention.
  • Bronchospasm: worsening of asthma or chronic obstructive pulmonary disease.
  • Hypotension: significant drop in blood pressure leading to fainting.
  • Depression or mood changes: rare but reported psychological effects.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Cardiovascular assessment: evaluate heart rate, blood pressure, and cardiac function.
  • Respiratory disease: avoid in patients with uncontrolled asthma or severe COPD.
  • Diabetes monitoring: may mask hypoglycaemia symptoms; adjust glucose checks.
  • Concomitant drugs: review other beta‑blockers or calcium channel blockers for additive effects.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Metoprolol Tartrate can interact with several medicines.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: combined use may cause excessive bradycardia.
  • Calcium channel blockers (verapamil, diltiazem): increase risk of heart block and hypotension.

Moderate Interactions (Monitor Closely)

  • Antidiabetic agents: may enhance hypoglycaemia; monitor glucose levels.
  • Antidepressants (SSRIs, SNRIs): may increase plasma metoprolol concentrations.
  • NSAIDs: can attenuate antihypertensive effect; watch blood pressure response.

Frequently Asked Questions

Metoprolol Medical Valley is prescribed to treat high blood pressure, chronic stable angina, post‑myocardial infarction management, heart failure with reduced ejection fraction, and certain cardiac arrhythmias such as atrial fibrillation. It works by lowering heart rate and cardiac output, helping to control these cardiovascular conditions.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, preventing adrenaline and noradrenaline from binding. This reduces cyclic AMP formation, leading to slower heart‑node firing, decreased contractility, and lower cardiac output, which together lower blood pressure and heart rate.

The dosage of Metoprolol Medical Valley is individualized by the prescribing clinician based on the specific indication, patient age, renal function, and response to therapy. Only a qualified healthcare professional can determine the appropriate dose and titration schedule.

Safety data for Metoprolol Tartrate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after careful assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) beta‑blocker, offering a favorable profile for patients with respiratory concerns compared with non‑selective agents like propranolol. Its once‑daily dosing and proven efficacy in hypertension, angina, and post‑MI care make it a common choice, though individual response and tolerability guide final selection.

Store Metoprolol Medical Valley at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency throughout its shelf life.

Metoprolol Medical Valley is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious risks include severe bradycardia, heart block, profound hypotension, bronchospasm in patients with asthma or COPD, and masking of hypoglycaemia symptoms in diabetic patients. Patients should seek immediate medical attention if they experience fainting, extreme fatigue, or respiratory difficulty.

Metoprolol Medical Valley should be avoided in individuals with known hypersensitivity to metoprolol or any component of the formulation, those with severe sinus bradycardia, second‑ or third‑degree heart block without a pacemaker, and patients with uncompensated heart failure or severe asthma unless a physician determines otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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