Product image of Metoprolol Medical Valley (Metoprolol Tartrate) supplied by GNH India

Metoprolol Medical Valley

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Medical Valley (Metoprolol Tartrate)

Metoprolol, the active ingredient in Metoprolol Medical Valley, is a beta blocker presented as a tablet for oral use. It treats hypertension, angina pectoris, myocardial infarction, heart failure and cardiac arrhythmias in adult patients.
GNH India supplies Metoprolol Medical Valley as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

  • Metoprolol is a selective β1‑adrenergic blocker used in cardiovascular conditions.
  • Hypertension: lowers blood pressure by reducing cardiac output and renin release.
  • Angina pectoris: decreases myocardial oxygen demand through heart‑rate reduction.
  • Myocardial infarction: improves post‑MI survival by limiting arrhythmias and workload.
  • Heart failure: reduces morbidity and mortality in chronic systolic failure.
  • Cardiac arrhythmias: controls ventricular rate in atrial fibrillation and other tachyarrhythmias.

How It Works

  • Metoprolol selectively antagonises β1‑adrenergic receptors located primarily in cardiac tissue. By blocking catecholamine binding, it reduces intracellular cyclic AMP, leading to decreased heart‑rate, contractility and conduction velocity. The resulting decline in myocardial oxygen consumption and cardiac output underlies its antihypertensive, anti‑anginal, anti‑infarct and anti‑arrhythmic effects.

Side Effects

Metoprolol may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue
  • Dizziness
  • Bradycardia
  • Gastrointestinal upset

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in patients with reactive airway disease

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety measures.
  • Monitor blood pressure: check regularly to ensure therapeutic control.
  • Assess heart rate: watch for bradycardia, particularly in patients with conduction disorders.
  • Use caution in asthma or COPD: β1‑selectivity may still affect bronchial tone.
  • Adjust dose in renal impairment: reduced clearance may require lower dosing.
  • Avoid abrupt discontinuation: taper gradually to prevent rebound hypertension.
  • Store at ambient temperature: keep below 25°C in the original pack, protect from moisture.

Avoid Interactions

Metoprolol can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: additive bradycardia.
  • Verapamil or diltiazem: increased risk of AV block.
  • Antidiabetic agents: may mask hypoglycaemia symptoms.
  • MAO inhibitors: enhanced hypotensive effect.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: additive blood‑pressure lowering.
  • NSAIDs: may reduce antihypertensive efficacy.
  • Digoxin: potential increase in serum digoxin levels.

Frequently Asked Questions

Metoprolol Medical Valley is prescribed for several cardiovascular conditions, including high blood pressure (hypertension), chest pain due to reduced blood flow (angina pectoris), recovery after a heart attack, chronic heart failure, and certain abnormal heart rhythms such as atrial fibrillation.

Metoprolol works by selectively blocking β1‑adrenergic receptors in the heart. This inhibition reduces the effects of adrenaline and noradrenaline, leading to a slower heart rate, decreased contractility, and lower cardiac output, which together lower blood pressure and lessen the heart’s oxygen demand.

The appropriate dose of Metoprolol Medical Valley is determined by the prescribing healthcare professional based on the patient’s specific condition, response to therapy, and any co‑existing medical issues. Dosage adjustments are made individually and should follow the prescriber’s instructions.

The safety of metoprolol during pregnancy or lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks before prescribing it to pregnant or nursing women, and alternative therapies may be considered when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) beta‑blocker, which generally results in fewer respiratory side effects compared with non‑selective agents like propranolol. Its pharmacokinetic profile allows once‑ or twice‑daily dosing, and it is widely used for both hypertension and heart‑failure management.

Metoprolol Medical Valley should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Metoprolol Medical Valley is taken orally, usually as a whole tablet with a glass of water. It can be taken with or without food, but consistency with meals may help reduce gastrointestinal discomfort. Patients should follow the dosing schedule prescribed by their clinician.

The most serious risks include severe bradycardia, heart block, marked hypotension, and bronchospasm, particularly in patients with underlying respiratory disease. Prompt medical attention is required if symptoms such as fainting, chest pain, severe shortness of breath, or sudden weakness occur.

Metoprolol should be avoided in individuals with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and patients with uncompensated heart failure or severe peripheral vascular disease unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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