Product image of Metoprolol Orion (Metoprolol Tartrate) supplied by GNH India

Metoprolol Orion

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Orion (Metoprolol Tartrate)

Metoprolol tartrate, the active ingredient in Metoprolol Orion, is a selective β1‑adrenergic receptor blocker presented as an oral tablet for systemic use. It is employed to lower high blood pressure, relieve angina pectoris, improve outcomes after myocardial infarction, support chronic heart failure management, and control certain cardiac arrhythmias.

GNH India supplies Metoprolol Orion as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Orion Corporation

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Metoprolol Orion is a beta‑blocker indicated for several cardiovascular conditions.
  • Hypertension: reduces systolic and diastolic blood pressure, decreasing cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Post‑myocardial infarction: improves survival and reduces recurrence of ischemic events.
  • Chronic heart failure: enhances left ventricular function and reduces hospitalization.
  • Cardiac arrhythmias: controls heart rate in supraventricular tachyarrhythmias.

How It Works

  • Metoprolol selectively antagonizes β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation of adenylate cyclase. This reduces cyclic AMP formation, leading to decreased intracellular calcium, slower sinoatrial node firing, lowered myocardial contractility, and reduced cardiac output, thereby lowering heart rate and blood pressure. The drug’s cardio‑selectivity minimizes effects on β2 receptors in the lungs, preserving bronchial tone.

Side Effects

Metoprolol Orion may be associated with a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Cold extremities (hands, feet)
  • Bradycardia (slow heart rate)
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Sleep disturbances or vivid dreams

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in asthmatic patients
  • Depression or mood changes
  • Exacerbation of heart failure
  • Allergic reactions (rash, angioedema)

Precautions & Warnings

  • When prescribing Metoprolol Orion, clinicians should consider several precautionary measures to ensure safe use.
  • Cardiovascular assessment: evaluate heart rate and blood pressure before initiation.
  • Respiratory conditions: use cautiously in patients with asthma or chronic obstructive pulmonary disease.
  • Diabetes monitoring: monitor blood glucose as β‑blockade may mask hypoglycemia symptoms.
  • Concomitant drugs: review for potential interactions, especially with other rate‑controlling agents.
  • Renal/hepatic impairment: dose adjustment may be required in severe dysfunction.
  • Store at below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Metoprolol Orion can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): risk of severe heart block.
  • Clonidine abrupt withdrawal: may cause rebound hypertension.
  • Insulin or oral hypoglycemics: mask hypoglycemia signs.
  • Potassium‑sparing diuretics: increase risk of hyperkalemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypotensive effect.
  • NSAIDs: may reduce antihypertensive efficacy.
  • Antidepressants (SSRIs): may increase bradycardia risk.

Frequently Asked Questions

Metoprolol Orion contains metoprolol tartrate, a beta‑blocker that is prescribed to treat high blood pressure, relieve angina pectoris, improve outcomes after a myocardial infarction, manage chronic heart failure, and control certain cardiac arrhythmias such as supraventricular tachycardia.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, reducing the effects of adrenaline and noradrenaline. This leads to lower heart rate, decreased contractility, and reduced cardiac output, which together lower blood pressure and myocardial oxygen demand.

The appropriate dose of Metoprolol Orion is determined by the prescribing healthcare professional based on the patient’s specific condition, response to therapy, and any comorbidities. Dosage may be adjusted over time to achieve optimal clinical effect.

Safety data for Metoprolol Orion in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Metoprolol Orion, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol Orion is cardio‑selective, primarily affecting β1 receptors, which generally results in fewer respiratory side effects compared with non‑selective beta‑blockers. Its pharmacokinetic profile allows once‑ or twice‑daily dosing, making it convenient for many patients, while other agents may have different half‑lives or receptor selectivity.

Metoprolol Orion should be stored at temperatures below 25 °C, in the original packaging, protected from moisture and direct light. Do not store in a bathroom or near a heat source, and keep out of reach of children.

Metoprolol Orion is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with asthma or COPD, and worsening of heart failure. Patients should seek immediate medical attention if they experience fainting, chest pain, difficulty breathing, or a rapid change in heart rate.

Metoprolol Orion is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and individuals in cardiogenic shock. Caution is also advised for patients with uncontrolled asthma.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Metoprolol Tartrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT