Product image of Metoprolol Retard Terapia (Metoprolol Tartrate) supplied by GNH India

Metoprolol Retard Terapia

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Retard Terapia (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Retard Terapia, is a beta blocker presented as an oral tablet for oral use. It is used to lower blood pressure, relieve angina and improve outcomes after heart attacks and in chronic heart failure.
GNH India supplies Metoprolol Retard Terapia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Terapia S.A.

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Indications & Clinical Uses

Metoprolol Tartrate acts on the cardiovascular system to control blood pressure and heart workload.

  • Hypertension: reduces systolic and diastolic pressure, helping prevent stroke and organ damage.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain during exertion.
  • Post‑myocardial infarction: lowers risk of recurrent infarction and improves survival.
  • Chronic heart failure: improves ventricular function and reduces hospitalization rates.

How It Works

  • Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, diminishing sympathetic stimulation. This leads to a slower heart rate, reduced contractile force, and lower renin release, collectively decreasing cardiac output and peripheral vascular resistance, which helps control blood pressure and myocardial oxygen consumption.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions.

Common Side Effects

  • Fatigue: feeling unusually tired or weak.
  • Dizziness: light‑headedness, especially when standing quickly.
  • Bradycardia: slower than normal heart rate.
  • Gastrointestinal upset: nausea or abdominal discomfort.

Serious or Rare Side Effects

  • Severe bradycardia or heart block requiring medical attention.
  • Marked hypotension leading to fainting or shock.
  • Bronchospasm in patients with asthma or chronic obstructive lung disease.

Precautions & Warnings

Before prescribing Metoprolol Tartrate, clinicians should consider several safety factors.

  • Blood pressure monitoring: ensure adequate control without excessive hypotension.
  • Cardiac function assessment: evaluate for heart block or severe bradycardia.
  • Concomitant beta‑blocker use: avoid duplicate therapy that may amplify effects.
  • Respiratory caution: use carefully in patients with asthma or COPD.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metoprolol Tartrate can interact with several medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: additive cardiac depression.
  • Calcium channel blockers (verapamil, diltiazem): risk of severe bradycardia and AV block.
  • Antidiabetic agents: may mask hypoglycaemia symptoms.

Moderate Interactions (Monitor Closely)

  • CYP2D6 inhibitors (e.g., fluoxetine, quinidine): increase metoprolol plasma levels.
  • NSAIDs: may reduce antihypertensive effect, requiring BP monitoring.

Frequently Asked Questions

Metoprolol Retard Terapia contains metoprolol tartrate, a beta‑blocker prescribed to manage high blood pressure, relieve angina pectoris, reduce risk after a myocardial infarction, and improve outcomes in chronic heart failure. It works by lowering heart rate and cardiac workload, helping to protect the cardiovascular system.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, decreasing the effects of adrenaline and noradrenaline. This reduces heart rate, myocardial contractility, and renin release, leading to lower blood pressure and reduced oxygen demand by the heart muscle.

The appropriate dose of Metoprolol Retard Terapia is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of metoprolol tartrate during pregnancy or lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks before prescribing it to pregnant or nursing individuals. Patients should discuss any concerns with their physician.

To request Metoprolol Retard Terapia, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol tartrate belongs to the beta‑blocker class, which primarily reduces heart rate and contractility. Compared with ACE inhibitors or calcium‑channel blockers, beta‑blockers are especially useful after myocardial infarction and in certain heart‑failure patients, but may be less effective as first‑line therapy for isolated hypertension in some guidelines.

Metoprolol Retard Terapia should be stored at room temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, direct sunlight and heat sources to maintain stability and potency.

Metoprolol Retard Terapia is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and rare allergic reactions. Patients should seek immediate medical attention if they experience fainting, severe dizziness, difficulty breathing, or signs of an allergic response.

Metoprolol Retard Terapia is contraindicated in individuals with known hypersensitivity to metoprolol or other beta‑blockers, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and patients with uncompensated heart failure or severe asthma/COPD where beta‑blockade could worsen symptoms.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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