Product image of Metoprolol Retard Viatris (Metoprolol Tartrate) supplied by GNH India

Metoprolol Retard Viatris

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Retard Viatris (Metoprolol Tartrate)

Metoprolol tartrate, the active ingredient in Metoprolol Retard Viatris, is a beta blocker presented as an extended‑release oral tablet for oral use. It is used to lower blood pressure, relieve angina, and improve outcomes after myocardial infarction and in chronic heart failure.

GNH India supplies Metoprolol Retard Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Gx

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Indications & Clinical Uses

Metoprolol tartrate is a selective β1‑adrenergic antagonist indicated for several cardiovascular conditions.

  • Hypertension: reduces systolic and diastolic pressure by decreasing cardiac output and renin release.
  • Angina pectoris: lessens myocardial oxygen demand, relieving chest pain during exertion.
  • Post‑myocardial infarction: lowers the risk of recurrent ischemic events and improves survival.
  • Chronic heart failure: improves ventricular function and reduces hospitalisation.
  • Cardiac arrhythmias: controls heart rate in supraventricular tachyarrhythmias.

How It Works

  • Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, diminishing sympathetic stimulation. This leads to a slower heart rate, reduced myocardial contractility, and decreased renin secretion from the kidneys, collectively lowering cardiac output and arterial pressure while improving ventricular efficiency.

Side Effects

Metoprolol tartrate may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal pain)
  • Headache

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Acute hypotension
  • Bronchospasm, especially in patients with asthma or COPD
  • Exacerbation of heart failure
  • Allergic reactions (rash, angioedema)
  • Depression or mood changes

Precautions & Warnings

Before initiating therapy, clinicians should evaluate cardiovascular status and comorbid conditions.

  • Cardiovascular assessment: confirm stable heart rate and blood pressure.
  • Respiratory caution: avoid in uncontrolled asthma or severe COPD.
  • Renal/hepatic impairment: consider dose adjustment.
  • Diabetes monitoring: watch for masked hypoglycaemia.
  • Discontinuation: taper gradually to prevent rebound hypertension.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Metoprolol tartrate can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Other AV‑node blockers (e.g., verapamil, diltiazem) – risk of profound bradycardia.
  • Clonidine withdrawal – may cause severe hypertension.
  • Insulin or oral hypoglycaemics – can mask hypoglycaemic symptoms.
  • MAO inhibitors – may enhance hypotensive effect.
  • Strong CYP2D6 inhibitors (e.g., paroxetine, fluoxetine) – increase metoprolol levels.

Moderate Interactions (Monitor Closely)

  • Diuretics – additive blood‑pressure lowering.
  • NSAIDs – may reduce antihypertensive efficacy.
  • Calcium‑channel blockers – potential for increased bradycardia.
  • Antithyroid drugs – may alter heart‑rate response.
  • Certain antidepressants – monitor for enhanced beta‑blockade.

Frequently Asked Questions

Metoprolol Retard Viatris contains metoprolol tartrate, a beta‑blocker prescribed to manage hypertension, angina pectoris, post‑myocardial infarction care, chronic heart failure, and certain cardiac arrhythmias. It works by slowing the heart rate and reducing the force of contraction, which helps lower blood pressure and myocardial oxygen demand.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in cardiac tissue. By inhibiting sympathetic stimulation, it decreases heart rate, myocardial contractility, and renin release from the kidneys, leading to reduced cardiac output and lower arterial pressure while improving heart‑failure symptoms.

The exact dose of Metoprolol Retard Viatris is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and any comorbidities. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for metoprolol tartrate in pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their physician, as metoprolol can be excreted in breast milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metoprolol Retard is a selective β1‑blocker, offering cardiac‑specific effects with fewer respiratory side effects compared with non‑selective agents like propranolol. Its extended‑release formulation provides once‑daily dosing, which can improve adherence relative to immediate‑release products that require multiple daily doses.

Metoprolol Retard should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, direct sunlight, and excessive heat to maintain product stability.

Metoprolol Retard is taken orally, usually once daily with or without food, as directed by the prescriber. Swallow the extended‑release tablet whole; do not crush, chew, or split it, as this can alter the release profile and increase the risk of side effects.

Serious risks include severe bradycardia, heart block, profound hypotension, bronchospasm in patients with asthma or COPD, and worsening heart failure. Patients should be monitored for these events, especially during dose initiation or when combined with other cardiac‑active medications.

Metoprolol Retard is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, in those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and in individuals with uncompensated heart failure or severe peripheral vascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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