Product image of Metoprolol Tartrate Accord Healthcare (Metoprolol Tartrate) supplied by GNH India

Metoprolol Tartrate Accord Healthcare

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Tartrate Accord Healthcare (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Tartrate Accord Healthcare, is a beta blocker presented as an oral tablet for oral use. It is employed to manage high blood pressure, chest pain, heart rhythm disorders, and post‑myocardial infarction care in adult patients.

GNH India supplies Metoprolol Tartrate Accord Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand through reliable logistics and dedicated support teams.

Manufacturer / TM Owner

Accord Healthcare Limited

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Indications & Clinical Uses

Metoprolol Tartrate is a selective β1‑adrenergic blocker used in several cardiovascular conditions to control heart rate and blood pressure.

  • Hypertension: lowers blood pressure by reducing heart rate and cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain during exertion.
  • Post‑myocardial infarction: improves survival by limiting adverse cardiac remodeling.
  • Heart failure: reduces symptoms and hospitalization risk by improving ventricular filling.
  • Cardiac arrhythmias: stabilizes abnormal heart rhythms, particularly supraventricular tachycardia.
  • Prevention of recurrent myocardial infarction: lowers risk of repeat heart attacks by reducing cardiac workload.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, diminishing sympathetic stimulation. This reduces heart rate, myocardial contractility, and consequently cardiac output, leading to lower arterial pressure and decreased myocardial oxygen consumption.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Fatigue
  • Dizziness
  • Bradycardia
  • Gastrointestinal upset

Serious or Rare Side Effects

  • Severe bradycardia
  • Heart block
  • Bronchospasm

Precautions & Warnings

Before prescribing Metoprolol Tartrate, clinicians should consider several safety aspects.

  • Dose adjustment in renal impairment: reduce dose based on creatinine clearance.
  • Monitor heart rate and blood pressure: ensure values remain within therapeutic range.
  • Caution in asthma or COPD: β1‑selectivity may not fully prevent bronchoconstriction.
  • Avoid abrupt discontinuation: taper gradually to prevent rebound tachycardia.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Metoprolol Tartrate can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Non‑selective beta blockers: additive negative chronotropic effects.
  • Calcium channel blockers (verapamil, diltiazem): may cause excessive bradycardia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: risk of enhanced hypotension.
  • Diuretics: may potentiate blood pressure lowering.
  • Antidiabetic agents: may mask hypoglycaemia symptoms.

Frequently Asked Questions

Metoprolol Tartrate Accord Healthcare is prescribed for hypertension, angina pectoris, post‑myocardial infarction management, chronic heart failure, and certain cardiac arrhythmias. It works by lowering heart rate and reducing the heart’s workload, helping to control blood pressure and relieve chest pain.

The drug selectively blocks β1‑adrenergic receptors in the heart, decreasing the effects of adrenaline and noradrenaline. This leads to a slower heart rate, reduced contractile force, and lower cardiac output, which together help to lower blood pressure and lessen myocardial oxygen demand.

The appropriate dose is determined by the prescribing clinician based on the patient’s medical condition, response to therapy, and any co‑existing health issues. Dosage may be started low and adjusted gradually; patients should follow the prescriber’s instructions exactly.

Safety data for Metoprolol Tartrate in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Healthcare providers weigh potential benefits against risks before prescribing to pregnant or nursing women.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol Tartrate is a β1‑selective blocker, offering cardiac‑focused effects with fewer respiratory side effects compared with non‑selective agents like propranolol. Its pharmacokinetic profile allows flexible dosing, but clinicians choose the most appropriate beta blocker based on individual patient characteristics and comorbidities.

Store the tablets at room temperature, below 25 °C, in the original container. Protect them from moisture and direct sunlight to maintain stability throughout the product’s shelf life.

Metoprolol Tartrate is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water; they are not intended for crushing or chewing unless specifically advised.

Serious adverse events can include severe bradycardia, heart block, and bronchospasm, especially in patients with underlying respiratory disease. Prompt medical attention is required if symptoms such as fainting, extreme fatigue, or difficulty breathing occur.

Patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe sinus bradycardia, second‑ or third‑degree heart block without a pacemaker, or uncontrolled asthma/COPD should avoid this medication unless a specialist advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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