Product image of Metoprolol Tartrate/Flexmed (Metoprolol Tartrate) supplied by GNH India

Metoprolol Tartrate/Flexmed

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Tartrate/Flexmed (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Tartrate/Flexmed, is a beta blocker presented as an injectable solution for intravenous use. It treats hypertension, angina pectoris, acute myocardial infarction and cardiac arrhythmias in adult patients.

GNH India supplies Metoprolol Tartrate/Flexmed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Flexmed Technologies & Innovations I.K.E

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metoprolol Tartrate is a selective β1‑adrenergic blocker used in cardiovascular conditions.

  • Hypertension: lowers systemic blood pressure by reducing cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Acute myocardial infarction: improves survival by limiting heart workload.
  • Cardiac arrhythmias: controls heart rate and stabilises rhythm in various tachyarrhythmias.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, leading to decreased heart rate, reduced myocardial contractility, and lower cardiac output. The resulting decline in renin release further contributes to blood‑pressure reduction, while the overall effect diminishes myocardial oxygen consumption and stabilises abnormal cardiac rhythms.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions.

Common Side Effects

  • Bradycardia: slower than normal heart rate.
  • Hypotension: low blood pressure causing dizziness.
  • Fatigue: feeling unusually tired.
  • Dizziness or light‑headedness.
  • Cold extremities: reduced peripheral circulation.
  • Nausea or mild gastrointestinal upset.

Serious or Rare Side Effects

  • Severe bradycardia or heart block.
  • Bronchospasm, especially in patients with asthma or COPD.
  • Acute heart failure or worsening of existing failure.
  • Allergic reactions such as rash, itching, or anaphylaxis.
  • Marked hypoglycaemia unmasked in diabetic patients.
  • Cardiogenic shock in rare cases.

Precautions & Warnings

Use Metoprolol Tartrate with careful clinical monitoring.

  • Cardiovascular assessment: evaluate heart rate and blood pressure before initiation.
  • Monitor heart rate and blood pressure regularly during therapy.
  • Caution in asthma or COPD: β1‑selectivity may not fully prevent bronchospasm.
  • Dose adjustment: consider renal or hepatic impairment when dosing.
  • Avoid abrupt discontinuation: taper to prevent rebound tachycardia.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Metoprolol Tartrate can interact with several drug classes.

Major Interactions (Avoid)

  • Other beta‑blockers: additive negative chronotropic effects.
  • Calcium‑channel blockers (verapamil, diltiazem): risk of severe bradycardia or AV block.
  • Clonidine withdrawal: may cause hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive response.
  • Diuretics: can potentiate hypotensive effects.
  • Digoxin: increased risk of bradycardia.
  • Certain antidepressants (e.g., SSRIs): may affect metabolism and plasma levels.

Frequently Asked Questions

Metoprolol Tartrate/Flexmed is an intravenous beta‑blocker indicated for the management of hypertension, angina pectoris, acute myocardial infarction and various cardiac arrhythmias. It helps lower blood pressure, reduce chest‑pain episodes, improve survival after a heart attack, and stabilise abnormal heart rhythms in adult patients.

The drug selectively blocks β1‑adrenergic receptors in the heart, which slows the heart rate, reduces the force of contraction, and lowers cardiac output. This also diminishes renin release from the kidneys, contributing to blood‑pressure reduction and decreasing myocardial oxygen demand, thereby alleviating angina and stabilising arrhythmias.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, severity, and response to therapy. Healthcare professionals tailor the regimen to individual needs, and the product label provides guidance for appropriate titration and monitoring.

Safety data for Metoprolol Tartrate in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Clinicians should weigh potential benefits against risks and consider alternative therapies when treating pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and necessary import documentation.

Metoprolol Tartrate is a short‑acting, β1‑selective blocker, offering rapid onset when given intravenously, which is useful in acute settings such as myocardial infarction. Compared with longer‑acting agents like atenolol or propranolol, it allows tighter titration and quicker withdrawal, but requires careful monitoring due to its potent cardiac effects.

Metoprolol Tartrate/Flexmed must be stored at 2‑8 °C, kept refrigerated, protected from light, and should never be frozen or shaken. The vial should remain in its original packaging until use to maintain stability and sterility.

The medication is supplied as a sterile injectable solution for intravenous infusion. It is administered by a qualified healthcare professional, typically via a controlled infusion pump or slow IV push, following the dosing instructions provided by the prescriber and adhering to aseptic technique.

Serious risks include severe bradycardia, heart block, bronchospasm in patients with reactive airway disease, acute heart failure, and rare allergic reactions such as anaphylaxis. Prompt recognition and immediate medical intervention are essential if any of these events occur.

Metoprolol Tartrate is contraindicated in patients with known hypersensitivity to the drug, those experiencing severe bradycardia, second‑ or third‑degree AV block without a pacemaker, cardiogenic shock, and in individuals with uncontrolled asthma or severe chronic obstructive pulmonary disease where β‑blockade may precipitate bronchospasm.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.