Product image of Metoprolol Tartrate Milpharm (Metoprolol Tartrate) supplied by GNH India

Metoprolol Tartrate Milpharm

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprolol Tartrate Milpharm (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprolol Tartrate Milpharm, is a beta blocker presented as a tablet for oral use. It is used to manage high blood pressure, angina, and certain heart rhythm disorders in adult patients.
GNH India supplies Metoprolol Tartrate Milpharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Milpharm Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metoprolol Tartrate acts on the cardiovascular system to control blood pressure and heart rhythm.

  • Hypertension: lowers systolic and diastolic pressure by reducing heart rate and cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Myocardial infarction: improves survival after heart attack by limiting workload on the heart.
  • Heart failure: helps reduce symptoms and hospitalizations by moderating heart rate.
  • Cardiac arrhythmias: stabilises abnormal heart rhythms by blocking β1‑adrenergic receptors.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, inhibiting the effects of endogenous catecholamines. This reduces heart rate, myocardial contractility, and conduction velocity, leading to decreased cardiac output and lower arterial pressure. The drug’s cardio‑selectivity limits activity on β2 receptors, preserving bronchial and peripheral vascular function in most patients.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions, most of which are dose‑related and reversible upon discontinuation.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Bradycardia (slow heart rate)
  • Mild depression or mood changes

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Acute heart failure exacerbation
  • Bronchospasm in susceptible individuals
  • Hypotension with syncope
  • Allergic reactions (rash, angioedema)
  • Hyperglycaemia in diabetic patients

Precautions & Warnings

Before initiating therapy, clinicians should assess patient history and comorbidities.

  • Cardiovascular disease: evaluate for bradycardia, heart block, or decompensated heart failure.
  • Respiratory conditions: use cautiously in asthma or COPD due to potential bronchoconstriction.
  • Diabetes: monitor blood glucose as β‑blockade may mask hypoglycaemia symptoms.
  • Pregnancy and lactation: prescribe only if benefits outweigh potential risks, as safety data are limited.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Metoprolol Tartrate can alter the pharmacokinetics or pharmacodynamics of several co‑administered agents.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): risk of severe bradycardia and AV block.
  • Antidiabetic sulfonylureas: may enhance hypoglycaemia.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): possible increase in plasma metoprolol levels.
  • NSAIDs: may reduce antihypertensive effect.
  • Antithyroid drugs: may blunt tachycardia response.

Frequently Asked Questions

Metoprolol Tartrate Milpharm is prescribed to treat high blood pressure, chronic stable angina, post‑myocardial infarction management, heart failure with reduced ejection fraction, and certain cardiac arrhythmias. It works by slowing the heart rate and reducing the force of contraction, which helps lower arterial pressure and myocardial oxygen demand.

The drug selectively blocks β1‑adrenergic receptors located primarily in the heart. By inhibiting the action of adrenaline and noradrenaline on these receptors, it reduces heart rate, myocardial contractility, and conduction velocity, leading to decreased cardiac output and lower blood pressure while preserving β2‑receptor activity in the lungs and vasculature.

The appropriate dose of Metoprolol Tartrate Milpharm is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and tolerability. Dosage adjustments are made according to blood pressure readings, heart rate, and clinical judgment, and should never be altered without professional guidance.

Safety data for Metoprolol Tartrate in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will evaluate each case individually and discuss alternative options when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Metoprolol Tartrate is a cardio‑selective β1‑blocker, offering a favorable profile for patients with hypertension or angina who also have respiratory concerns, as it spares β2 receptors. Compared with non‑selective agents like propranolol, it tends to cause fewer bronchospastic events while providing comparable heart‑rate control.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure the packaging remains tightly closed to maintain product stability throughout its shelf life.

Metoprolol Tartrate Milpharm is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious adverse events include severe bradycardia, heart block, hypotension, acute heart‑failure exacerbation, and bronchospasm in patients with underlying respiratory disease. Prompt medical attention is required if symptoms such as fainting, chest pain, or difficulty breathing occur.

Metoprolol Tartrate is contraindicated in patients with known hypersensitivity to the drug, those with severe bradycardia (heart rate < 45 bpm), second‑ or third‑degree atrioventricular block without a pacemaker, and individuals in cardiogenic shock. Caution is also advised for patients with uncontrolled asthma or chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.