Product image of Metoprolol Teva (Metoprolol Succinate) supplied by GNH India

Metoprolol Teva

Active Ingredient:
Metoprolol Succinate
Origin:
EU

Metoprolol Teva (Metoprolol Succinate)

Metoprolol succinate, the active ingredient in Metoprolol Teva, is a beta blocker presented as an oral tablet for oral use. It is used to lower high blood pressure, relieve chest pain from angina, and improve outcomes in chronic heart failure and after myocardial infarction. The medication works by selectively blocking β1‑adrenergic receptors, reducing heart rate and myocardial workload.

GNH India supplies Metoprolol Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Sweden Ab

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Indications & Clinical Uses

Metoprolol Teva is a selective β1‑blocker indicated for several cardiovascular conditions.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain during exertion.
  • Chronic heart failure: improves left‑ventricular function and reduces hospitalization.
  • Post‑myocardial infarction: lowers the chance of recurrent ischemic events and mortality.

How It Works

  • Metoprolol succinate selectively antagonizes β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation of adenylate cyclase. This reduces cyclic AMP formation, leading to decreased intracellular calcium, slower heart rate, reduced contractility, and lower myocardial oxygen consumption, thereby helping control blood pressure and alleviate cardiac workload.

Side Effects

Metoprolol Teva may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue: feeling unusually tired or weak.
  • Dizziness: light‑headedness, especially when standing quickly.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced blood flow to hands and feet.
  • Gastrointestinal upset: nausea or abdominal discomfort.

Serious or Rare Side Effects

  • Severe bradycardia: heart rate dropping to dangerously low levels.
  • Heart block: impaired electrical conduction in the heart.
  • Hypotension: markedly low blood pressure causing fainting.
  • Bronchospasm: tightening of airway muscles, especially in asthmatic patients.
  • Depression or mood changes: new or worsening depressive symptoms.

Precautions & Warnings

Before initiating Metoprolol Teva, clinicians should assess patient history and monitor specific parameters.

  • Cardiovascular assessment: evaluate heart rate, blood pressure, and conduction abnormalities.
  • Respiratory conditions: use cautiously in patients with asthma or chronic obstructive pulmonary disease.
  • Diabetes management: monitor blood glucose as β‑blockade may mask hypoglycaemia symptoms.
  • Thyroid disorders: adjust dose in hyper‑ or hypothyroid patients.
  • Drug discontinuation: taper gradually to avoid rebound tachycardia or hypertension.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metoprolol Teva can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): profound heart‑rate slowing and AV‑block risk.
  • Antidiabetic agents: may mask hypoglycaemia signs.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): possible increase in plasma metoprolol levels.
  • NSAIDs: may reduce antihypertensive effect.
  • Antihypertensives (ACE inhibitors, ARBs): monitor for excessive blood‑pressure lowering.

Frequently Asked Questions

Metoprolol Teva is prescribed for high blood pressure (hypertension), chest pain caused by angina pectoris, chronic heart failure, and to reduce the risk of further cardiac events after a myocardial infarction. It works by lowering heart rate and decreasing the heart’s workload, which helps manage these cardiovascular conditions.

Metoprolol succinate is a selective β1‑adrenergic receptor antagonist. By blocking these receptors in the heart, it reduces the effects of adrenaline and noradrenaline, leading to a slower heart rate, decreased contractility, and lower blood pressure. This results in reduced oxygen demand by the heart muscle and improved cardiac efficiency.

The appropriate dose of Metoprolol Teva is determined by the prescribing healthcare professional based on the patient’s specific condition, response to therapy, and any other medical considerations. Dosage adjustments are made individually, and patients should follow the prescriber’s instructions without self‑adjusting the amount.

Safety of Metoprolol Teva during pregnancy or lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks before prescribing it to pregnant or nursing individuals. Patients should discuss their situation with a qualified clinician to make an informed decision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metoprolol Teva is a cardio‑selective (β1‑specific) blocker, which generally offers fewer respiratory side effects compared with non‑selective beta blockers like propranolol. Its extended‑release formulation provides once‑daily dosing, improving adherence for chronic conditions such as hypertension and heart failure.

Metoprolol Teva should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture, heat, and direct sunlight to maintain stability and potency throughout the shelf life.

Metoprolol Teva is taken orally, usually as a whole tablet swallowed with water. It is commonly prescribed for once‑daily dosing due to its extended‑release formulation, but the exact schedule should follow the prescriber’s directions.

Serious risks include severe bradycardia, heart block, marked hypotension, and bronchospasm in patients with underlying respiratory disease. Patients should be monitored for signs of these conditions, especially during dose initiation or when combined with other medications that affect heart rate or blood pressure.

Metoprolol Teva is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and individuals experiencing cardiogenic shock. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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