Product image of Metoprololo Eg (Metoprolol Tartrate) supplied by GNH India

Metoprololo Eg

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprololo Eg (Metoprolol Tartrate)

Metoprolol, the active ingredient in Metoprololo Eg, is a beta blocker presented as an oral dosage form for oral use. It is employed to manage hypertension, angina pectoris, heart failure and to improve outcomes after myocardial infarction.
GNH India supplies Metoprololo Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg S.P.A.

1
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Indications & Clinical Uses

  • Metoprolol acts on the cardiovascular system to control blood pressure and heart workload.
  • Hypertension: lowers systemic blood pressure and reduces cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Heart failure: improves ventricular function and reduces hospitalisation rates.
  • Post‑myocardial infarction: lowers the risk of recurrent cardiac events and mortality.

How It Works

  • Metoprolol is a selective β1‑adrenergic receptor antagonist. By blocking β1 receptors in the heart, it reduces heart rate, contractility, and cardiac output, leading to decreased myocardial oxygen consumption and lower arterial pressure. The selectivity limits activity on β2 receptors, minimizing bronchial effects compared with non‑selective beta blockers.

Side Effects

Metoprolol may cause a range of adverse reactions, most of which are dose‑related and reversible upon discontinuation.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Cold extremities or peripheral vasoconstriction
  • Bradycardia (slow heart rate)
  • Gastrointestinal upset such as nausea or abdominal discomfort
  • Headache

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Exacerbation of heart failure
  • Bronchospasm in patients with reactive airway disease
  • Allergic reactions including rash or angioedema
  • Depression or mood changes

Precautions & Warnings

  • Metoprolol should be used with careful clinical assessment and monitoring.
  • Cardiovascular assessment: evaluate heart rate and blood pressure before initiation.
  • Respiratory conditions: avoid in patients with severe asthma or chronic obstructive pulmonary disease without specialist advice.
  • Diabetes monitoring: monitor blood glucose as beta‑blockade may mask hypoglycaemia symptoms.
  • Renal/hepatic impairment: dose adjustment may be required in reduced organ function.
  • Concomitant drugs: review other medications that affect heart rate or blood pressure.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metoprolol can interact with several drug classes, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Verapamil or diltiazem: combined use may cause severe bradycardia or AV block.
  • Clonidine: abrupt discontinuation after beta‑blocker therapy can precipitate rebound hypertension.
  • Other beta‑blockers: additive negative chronotropic effects increase risk of heart block.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance hypotensive response.
  • ACE inhibitors or ARBs: additive blood‑pressure lowering effect requires monitoring.
  • Antidiabetic agents: beta‑blockade can mask hypoglycaemia signs, necessitating glucose checks.

Frequently Asked Questions

Metoprololo Eg contains metoprolol tartrate, a beta‑blocker indicated for the treatment of hypertension, angina pectoris, chronic heart failure, and for secondary prevention after a myocardial infarction. It helps lower blood pressure, reduce chest pain, improve heart function, and decrease the risk of future cardiac events.

Metoprolol selectively blocks β1‑adrenergic receptors in the heart, which reduces heart rate, myocardial contractility, and cardiac output. This leads to lower oxygen demand by the heart muscle and a reduction in systemic blood pressure, providing therapeutic benefit in cardiovascular diseases.

The appropriate dose of Metoprololo Eg is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and any co‑existing health issues. Dosage may be adjusted over time to achieve optimal blood‑pressure control or symptom relief.

Safety data for metoprolol in pregnancy and lactation are limited. The drug should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will evaluate each case individually and discuss alternatives when appropriate.

To request Metoprololo Eg, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) beta‑blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. Its pharmacokinetic profile provides once‑ or twice‑daily dosing, which can improve adherence. Choice of beta‑blocker depends on the patient’s comorbidities, tolerance and clinical goals.

Metoprololo Eg should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain its stability and potency throughout its shelf life.

Metoprololo Eg is taken orally, usually with or without food, as directed by the prescribing clinician. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious adverse events may include severe bradycardia, heart block, marked hypotension, worsening heart failure, bronchospasm in susceptible individuals, and allergic reactions such as rash or angioedema. Patients should seek immediate medical attention if they experience fainting, rapid weight gain, difficulty breathing, or signs of an allergic response.

Metoprololo Eg is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree atrioventricular block, cardiogenic shock, or overt decompensated heart failure. Caution is also advised for individuals with severe asthma or chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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