Metoprololsuccinat Dura (Metoprolol Tartrate)

Metoprolol selectively blocks β1‑adrenergic receptors in the heart, preventing catecholamines like adrenaline from increasing heart rate and contractility. This leads to reduced cardiac output, lower blood pressure, and decreased myocardial oxygen demand. It also diminishes renin release from the kidneys, contributing to its antihypertensive effect.

The appropriate dose of Metoprololsuccinat Dura is individualized by a qualified prescriber based on the patient’s clinical condition, response, and tolerability. Dosage may be adjusted over time, and patients should follow the prescribing physician’s instructions without self‑adjusting the amount.

Safety data for metoprolol in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will assess each case and discuss alternatives if appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metoprolol is a cardio‑selective β1‑blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. Its pharmacokinetic profile provides once‑ or twice‑daily dosing, and it is widely used for heart‑failure management, whereas some beta blockers are preferred for migraine prophylaxis or tremor control.

Store Metoprololsuccinat Dura at temperatures below 25 °C in a dry place. Keep the product in its original packaging, protect it from moisture, heat, and direct sunlight, and ensure the container is tightly closed when not in use.

Metoprololsuccinat Dura is taken orally, usually with or without food, as directed by the prescribing clinician. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious adverse events may include severe bradycardia, symptomatic hypotension, worsening heart failure, bronchospasm in patients with reactive airway disease, and rare allergic reactions such as angioedema. Patients should seek immediate medical attention if they experience fainting, chest pain, difficulty breathing, or swelling of the face or throat.

Metoprololsuccinat Dura is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, cardiogenic shock, or overt decompensated heart failure. Caution is also advised for individuals with uncontrolled asthma or severe peripheral vascular disease.