Product image of Metoprololsuccinat Stada (Metoprolol Tartrate) supplied by GNH India

Metoprololsuccinat Stada

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprololsuccinat Stada (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprololsuccinat Stada, is a beta‑blocker presented as oral tablets for oral use. It is employed to lower blood pressure, relieve angina and improve outcomes in heart failure patients.
GNH India supplies Metoprololsuccinat Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Gmbh

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Indications & Clinical Uses

Metoprolol Tartrate acts on the cardiovascular system to control blood pressure and reduce cardiac workload.

  • Hypertension: lowers systolic and diastolic pressure, decreasing long‑term cardiovascular risk.
  • Angina pectoris: reduces myocardial oxygen demand, alleviating chest pain episodes.
  • Post‑myocardial infarction: improves survival by limiting arrhythmias and remodeling.
  • Chronic heart failure: enhances left‑ventricular function and reduces hospitalisation rates.

How It Works

  • Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in cardiac tissue, decreasing heart rate, myocardial contractility and renin release. This results in reduced cardiac output and lower systemic vascular resistance, thereby diminishing blood pressure and myocardial oxygen consumption.

Side Effects

Metoprolol Tartrate may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal discomfort)
  • Headache

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in asthmatic patients
  • Acute decompensated heart failure
  • Allergic reactions (rash, angioedema)
  • Depression or mood changes

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Monitor heart rate: ensure rate does not fall below recommended limits.
  • Assess blood pressure: watch for excessive hypotension after dose changes.
  • Use caution in asthma or chronic obstructive pulmonary disease: β1‑selectivity may not fully prevent bronchospasm.
  • Avoid abrupt discontinuation: taper dose to prevent rebound hypertension or tachycardia.
  • Adjust dose in renal impairment: reduced clearance may increase exposure.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Metoprolol Tartrate can interact with several drug classes, altering its efficacy or safety.

Major Interactions (Avoid)

  • Other β‑blockers or non‑selective β‑blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): potentiate heart‑rate slowing and AV‑block.
  • Antiarrhythmic agents (class I): increase risk of conduction disturbances.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive effect.
  • Diuretics: combined effect on blood pressure and electrolytes requires monitoring.
  • Antidiabetic agents (insulin, sulfonylureas): may mask hypoglycaemia symptoms.

Frequently Asked Questions

Metoprololsuccinat Stada, containing metoprolol tartrate, is prescribed for high blood pressure, angina pectoris, post‑myocardial infarction management and chronic heart failure. It helps control heart rate and reduce the workload on the heart, improving overall cardiovascular stability.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, decreasing heart rate, contractility and renin release. This lowers cardiac output and systemic vascular resistance, which together reduce blood pressure and myocardial oxygen demand.

The dose of Metoprololsuccinat Stada is individualized by the prescribing clinician based on the patient’s condition, response and tolerability. Only a qualified health professional should determine the appropriate dosing regimen.

Safety data for metoprolol in pregnancy are limited, and the drug is generally classified as use‑only if the potential benefit outweighs risk. It is excreted in breast milk, so breastfeeding mothers should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol is a cardio‑selective (β1‑selective) beta‑blocker, offering fewer respiratory side effects than non‑selective agents such as propranolol. It is commonly chosen for patients with hypertension, angina or heart failure where β1‑selectivity provides a favorable safety profile.

Store the tablets at room temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure the packaging is tightly closed to maintain product stability.

Metoprololsuccinat Stada is taken orally, usually with or without food, as directed by the prescriber. Swallow the tablet whole with a full glass of water; do not crush or chew unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and worsening heart failure. Patients should be monitored for these events, especially during dose initiation or adjustment.

Metoprolol is contraindicated in patients with known hypersensitivity to the drug, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, cardiogenic shock, or overt decompensated heart failure. Caution is also advised in individuals with asthma or severe chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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