Product image of Metoprololtartraat Aurobindo (Metoprolol Tartrate) supplied by GNH India

Metoprololtartraat Aurobindo

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprololtartraat Aurobindo (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprololtartraat Aurobindo, is a beta blocker presented as a tablet for oral use. It is used to manage high blood pressure, angina, and certain cardiac rhythm disorders in adult patients. GNH India supplies Metoprololtartraat Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

Metoprololtartraat Aurobindo is a selective β1‑blocker that acts on the cardiovascular system to control pressure and rhythm.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Myocardial infarction: improves survival by reducing cardiac workload after an acute event.
  • Heart failure: helps improve left‑ventricular function and symptoms.
  • Cardiac arrhythmias: controls heart rate in supraventricular tachycardia and atrial fibrillation.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This reduces heart rate, myocardial contractility, and conduction velocity, leading to decreased cardiac output and lower arterial pressure while preserving β2‑mediated bronchial tone.

Side Effects

Metoprololtartraat Aurobindo may cause a range of adverse reactions.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness, especially on standing
  • Cold extremities or reduced peripheral circulation
  • Gastrointestinal upset such as nausea or abdominal discomfort
  • Sleep disturbances including vivid dreams
  • Mild bradycardia (heart rate <60 bpm)

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Acute heart failure exacerbation
  • Bronchospasm in patients with reactive airway disease
  • Hypotensive crisis with syncope
  • Depression or mood changes
  • Allergic reactions such as rash, angioedema, or anaphylaxis

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Cardiac function: assess for decompensated heart failure or severe bradycardia.
  • Respiratory status: avoid in uncontrolled asthma or chronic obstructive pulmonary disease.
  • Diabetes: monitor blood glucose as β‑blockade may mask hypoglycaemia symptoms.
  • Thyroid disease: use cautiously in hyper‑ or hypothyroidism.
  • Concomitant drugs: review for interactions that may exacerbate bradycardia or hypotension.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metoprololtartraat Aurobindo can interact with several medicines.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): profound AV‑node depression.
  • Antidiabetic agents: may mask hypoglycaemia signs.
  • Potassium‑sparing diuretics: risk of hyperkalaemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: enhanced blood pressure lowering.
  • NSAIDs: may reduce antihypertensive effect.
  • Antidepressants (SSRIs, SNRIs): possible increase in plasma metoprolol levels.
  • Antithyroid drugs: may alter heart rate response.

Frequently Asked Questions

Metoprololtartraat Aurobindo is prescribed to treat high blood pressure, chronic stable angina, post‑myocardial infarction management, heart failure with reduced ejection fraction, and certain cardiac arrhythmias such as atrial fibrillation. It works by lowering heart rate and reducing the heart’s workload.

Metoprolol Tartrate selectively blocks β1‑adrenergic receptors in the heart, preventing catecholamines from increasing heart rate and contractility. This leads to a slower pulse, reduced myocardial oxygen demand, and lower arterial pressure, helping to control cardiovascular conditions.

The appropriate dose is determined by the prescribing clinician based on the patient’s condition, response, and tolerability. Dosage may be started low and titrated upward, but exact regimens should only be set by a qualified healthcare professional.

Safety in pregnancy and lactation has not been definitively established. Clinicians weigh potential benefits against risks, and the drug is generally used only if clearly needed. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprololtartraat Aurobindo is a selective β1‑blocker, offering cardiac‑specific effects with less impact on bronchial β2 receptors compared with non‑selective agents like propranolol. This selectivity can make it preferable for patients with respiratory concerns, while still providing effective blood‑pressure and anti‑anginal control.

Store the tablets at ambient temperature, preferably below 25 °C, in the original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children.

The medication is taken orally, usually with a glass of water. It can be taken with or without food, but consistency with meals helps maintain steady absorption. Patients should follow the dosing schedule prescribed by their healthcare provider.

Serious adverse events include severe bradycardia, heart block, hypotensive crisis, worsening heart failure, bronchospasm in susceptible individuals, and rare allergic reactions such as anaphylaxis. Prompt medical attention is required if any of these symptoms occur.

Patients with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, decompensated heart failure, uncontrolled asthma or severe chronic obstructive pulmonary disease, and those experiencing cardiogenic shock should avoid this medication unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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