Product image of Metoprololtartrat Heumann (Metoprolol Tartrate Ph. Eur.) supplied by GNH India

Metoprololtartrat Heumann

Active Ingredient:
Metoprolol Tartrate Ph. Eur.
Origin:
EU

Metoprololtartrat Heumann (Metoprolol Tartrate Ph. Eur.)

Metoprolol tartrate, the active ingredient in Metoprololtartrat Heumann, is a beta‑blocker presented as an oral tablet for oral use. It is used to treat hypertension, angina, post‑myocardial‑infarction care, chronic heart failure and certain cardiac arrhythmias in adult patients.

GNH India supplies Metoprololtartrat Heumann as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Heumann Pharma Gmbh & Co. Generica Kg

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Indications & Clinical Uses

  • Metoprolol tartrate acts on the cardiovascular system to control blood pressure and heart workload.
  • Hypertension: lowers systolic and diastolic pressure by reducing heart rate and contractility.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Post‑myocardial infarction: improves survival by limiting ventricular remodeling.
  • Chronic heart failure: enhances left‑ventricular function and reduces hospitalization risk.
  • Cardiac arrhythmias: stabilises heart rhythm by slowing conduction through the AV node.

How It Works

  • Metoprolol tartrate selectively blocks β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This reduces heart rate, myocardial contractility, and renin release, leading to decreased cardiac output and oxygen consumption, thereby lowering blood pressure and alleviating myocardial stress.

Side Effects

Metoprolol tartrate may cause a range of adverse reactions.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal upset (nausea, abdominal pain)
  • Sleep disturbances or vivid dreams

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm, especially in asthmatic patients
  • Acute decompensated heart failure
  • Allergic reactions (rash, angioedema)
  • Depression or mood changes

Precautions & Warnings

Before prescribing Metoprolol tartrate, clinicians should evaluate patient-specific factors.

  • Cardiac assessment: confirm baseline heart rate and blood pressure.
  • Monitor regularly: check vital signs and ECG during dose adjustments.
  • Respiratory caution: use carefully in patients with asthma or COPD.
  • Discontinuation: avoid abrupt withdrawal to prevent rebound tachycardia.
  • Dose adjustment: consider renal or hepatic impairment when titrating.
  • Store at ambient temperature: keep in the original container, protect from moisture.

Avoid Interactions

Metoprolol tartrate can interact with several drug classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers (e.g., propranolol)
  • Calcium‑channel blockers verapamil or diltiazem
  • Clonidine (abrupt discontinuation may cause hypertension)
  • Insulin or oral hypoglycemics (mask hypoglycemia symptoms)
  • Monoamine‑oxidase inhibitors (risk of severe hypotension)

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs (enhanced hypotensive effect)
  • Diuretics (potentiates blood pressure lowering)
  • Antidepressants (SSRIs, SNRIs) may increase bradycardia risk
  • Lithium (possible increase in serum levels)
  • NSAIDs (may reduce antihypertensive efficacy)

Frequently Asked Questions

Metoprololtartrat Heumann contains metoprolol tartrate, a beta‑blocker indicated for hypertension, angina pectoris, post‑myocardial‑infarction care, chronic heart failure, and certain cardiac arrhythmias. It helps control blood pressure and reduces the heart's workload in adult patients.

Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, decreasing the effects of adrenaline and noradrenaline. This leads to a slower heart rate, reduced contractile force, lower cardiac output, and diminished oxygen demand, which together lower blood pressure and relieve chest pain.

The appropriate dose of Metoprololtartrat Heumann is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and any comorbidities. Patients should follow the dosage instructions provided by their healthcare professional.

Safety data for metoprolol tartrate in pregnancy and lactation are limited. Clinicians should weigh potential benefits against risks before prescribing to pregnant or nursing women, and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metoprolol tartrate is a selective β1‑blocker, offering cardiac‑specific effects with fewer respiratory side effects compared with non‑selective agents like propranolol. Its pharmacokinetic profile allows once‑ or twice‑daily dosing, making it a common choice for hypertension and heart‑failure management.

Metoprololtartrat Heumann should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain stability.

The medication is supplied as oral tablets and is taken by mouth with or without food, as directed by the prescriber. Swallow the tablet whole; do not crush or chew unless specifically instructed.

Serious adverse events can include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and acute decompensated heart failure. Patients should seek immediate medical attention if they experience fainting, severe shortness of breath, or rapid weight gain.

Metoprololtartrat Heumann is contraindicated in patients with known hypersensitivity to metoprolol or other beta‑blockers, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, and individuals in cardiogenic shock. Caution is advised for patients with asthma, severe peripheral vascular disease, or uncontrolled heart failure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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