Product image of Metoprololtartrat Hexal (Metoprolol Tartrate) supplied by GNH India

Metoprololtartrat Hexal

Active Ingredient:
Metoprolol Tartrate
Origin:
EU

Metoprololtartrat Hexal (Metoprolol Tartrate)

Metoprolol Tartrate, the active ingredient in Metoprololtartrat Hexal, is a beta blocker presented as a tablet for oral use. It lowers blood pressure, relieves angina and supports heart‑failure therapy in adult patients.
GNH India supplies Metoprololtartrat Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Pharma Gmbh

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Indications & Clinical Uses

  • Metoprololtartrat Hexal is a selective β1‑adrenergic blocker used in several cardiovascular conditions.
  • Hypertension: lowers systolic and diastolic pressure by reducing heart rate and cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Post‑myocardial infarction: improves survival by limiting arrhythmias and remodeling.
  • Chronic heart failure: enhances ventricular function and reduces hospitalization risk.

How It Works

  • Metoprolol Tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This reduces heart rate, myocardial contractility, and renin release, leading to decreased cardiac output and lower arterial pressure, while also diminishing myocardial oxygen consumption.

Side Effects

Metoprololtartrat Hexal may cause a range of adverse reactions.

Common Side Effects

  • Fatigue or tiredness
  • Dizziness or light‑headedness
  • Bradycardia (slow heart rate)
  • Cold extremities
  • Headache
  • Gastrointestinal discomfort (nausea, abdominal pain)

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm in patients with asthma or COPD
  • Acute heart failure exacerbation
  • Allergic reactions (rash, angioedema)
  • Depression or mood changes

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.
  • Monitor blood pressure: ensure adequate control without excessive hypotension.
  • Assess heart rate: watch for bradycardia, especially in patients with conduction disorders.
  • Use caution in asthma or COPD: β1‑selectivity may not fully prevent bronchospasm.
  • Avoid abrupt discontinuation: taper to prevent rebound hypertension or tachycardia.
  • Adjust dose in renal impairment: reduced clearance may require lower dosing.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metoprololtartrat Hexal can interact with several drug classes.

Major Interactions (Avoid)

  • Verapamil or diltiazem: additive negative‑inotropic and bradycardic effects.
  • Class IA antiarrhythmics (e.g., quinidine): increased risk of conduction abnormalities.
  • Clonidine abrupt withdrawal: may cause severe hypertension.
  • Insulin or oral hypoglycemics: can mask hypoglycaemia symptoms.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypotensive response.
  • Diuretics (especially thiazides): risk of electrolyte disturbances.
  • NSAIDs: may reduce antihypertensive efficacy.

Frequently Asked Questions

Metoprololtartrat Hexal contains metoprolol tartrate, a selective β1‑blocker prescribed to manage high blood pressure, relieve angina pectoris, improve outcomes after a myocardial infarction, and treat chronic heart failure. It may also be used in certain cardiac arrhythmias under specialist supervision.

Metoprolol Tartrate blocks β1‑adrenergic receptors in the heart, preventing catecholamines such as adrenaline from increasing heart rate and contractility. This results in lower cardiac output, reduced myocardial oxygen demand, and a drop in systemic blood pressure, helping to control cardiovascular stress.

The exact dose of Metoprololtartrat Hexal is determined by the prescribing clinician based on the individual’s condition, response, and any comorbidities. Dosage may be adjusted over time, and patients should follow the prescriber’s instructions without self‑adjusting the amount.

Safety data for metoprolol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives and risks with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements) and the necessary import documentation.

Metoprolol is a cardio‑selective (β1‑specific) blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. Its relatively short half‑life allows flexible dosing, and it is widely studied for post‑MI and heart‑failure indications, making it a common first‑line choice in many guidelines.

Store the tablets below 25 °C in a dry place, preferably in the original container to protect them from moisture and light. Keep out of reach of children and do not use the product after the expiry date printed on the packaging.

Metoprololtartrat Hexal is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious adverse events include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with reactive airway disease, and rare allergic reactions such as angioedema. Patients should seek immediate medical attention if they experience fainting, severe shortness of breath, or swelling of the face or throat.

Metoprololtartrat Hexal is contraindicated in patients with known hypersensitivity to metoprolol or any excipients, those with severe bradycardia (heart rate < 45 bpm), second‑ or third‑degree atrioventricular block without a pacemaker, and individuals in cardiogenic shock. Caution is also advised for patients with uncontrolled asthma or severe peripheral vascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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