Product image of Metronidazol Arena (Metronidazole) supplied by GNH India

Metronidazol Arena

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Arena (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Arena, is a nitroimidazole antibiotic presented as an oral dosage form for oral use. It treats a range of anaerobic bacterial and protozoal infections in adults and children as prescribed by a healthcare professional.

GNH India supplies Metronidazol Arena as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers. Its distribution network ensures timely delivery and regulatory compliance across multiple regions.

Manufacturer / TM Owner

Arena Group S.A

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Indications & Clinical Uses

Metronidazole is used to treat infections caused by anaerobic bacteria and protozoa.

  • Bacterial vaginosis: eliminates the anaerobic bacteria responsible for the condition, relieving symptoms.
  • Trichomoniasis: eradicates Trichomonas vaginalis, resolving vaginal discharge and irritation.
  • Amoebiasis: destroys Entamoeba histolytica trophozoites, treating intestinal and extra‑intestinal disease.
  • Giardiasis: clears Giardia lamblia infection, reducing diarrhea and malabsorption.
  • Anaerobic bacterial infections: targets a broad spectrum of anaerobes in intra‑abdominal, skin and oral infections.
  • Clostridioides difficile infection: suppresses toxin‑producing C. difficile, aiding clinical recovery.

How It Works

  • Metronidazole is reduced within anaerobic microorganisms, generating reactive nitro radicals that damage DNA and inhibit nucleic acid synthesis. This leads to strand breakage and cell death, selectively affecting anaerobic bacteria and protozoa while sparing most aerobic cells.

Side Effects

Metronidazole may cause a variety of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient metallic sensation in the mouth.
  • Diarrhea: loose stools that may be watery.
  • Abdominal cramps: discomfort or cramping in the abdomen.
  • Headache: mild to moderate headache.
  • Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects

  • Seizures: rare neurologic events requiring immediate care.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis, rash, or swelling.
  • Stevens‑Johnson syndrome: serious skin and mucous membrane disorder.
  • Hepatotoxicity: liver enzyme elevation or injury.
  • Blood dyscrasias: neutropenia, thrombocytopenia, or anemia.

Precautions & Warnings

Before using Metronidazol Arena, consider the following safety measures.

  • Pregnancy: consult a healthcare provider as safety data are limited.
  • Breastfeeding: discuss risks with a clinician; drug may pass into milk.
  • Alcohol consumption: avoid alcohol during treatment and for at least 48 hours after to prevent a disulfiram‑like reaction.
  • Liver disease: monitor hepatic function; dose adjustment may be needed.
  • Renal impairment: assess renal function and adjust dose if required.
  • Allergy: discontinue immediately if hypersensitivity signs appear.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Metronidazol Arena can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Alcohol: may cause severe disulfiram‑like reaction with flushing, nausea and tachycardia.
  • Warfarin: can increase anticoagulant effect; monitor INR closely.
  • Lithium: may raise lithium levels, increasing risk of toxicity.

Moderate Interactions (Monitor Closely)

  • Cimetidine: may elevate metronidazole plasma concentrations.
  • Phenytoin: may reduce metronidazole efficacy.
  • Phenobarbital: may lower metronidazole levels, potentially decreasing effectiveness.

Frequently Asked Questions

Metronidazol Arena is prescribed for infections caused by anaerobic bacteria and certain protozoa. Common indications include bacterial vaginosis, trichomoniasis, amoebiasis, giardiasis, intra‑abdominal anaerobic infections, and Clostridioides difficile infection, all of which require a clinician’s diagnosis and prescription.

Metronidazole enters anaerobic microorganisms and is reduced to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, causing strand breakage and cell death. The mechanism selectively targets anaerobic bacteria and protozoa while sparing most aerobic cells.

The exact dose of Metronidazol Arena is set by the prescribing healthcare professional based on the specific infection, its severity, the patient’s age, weight, renal and hepatic function, and any concomitant medications. Patients should follow the prescriber’s instructions precisely.

Safety data for metronidazole in pregnancy are limited, so a prescriber should evaluate the risk‑benefit ratio before use. The drug can be excreted in breast milk; therefore, breastfeeding mothers should discuss potential risks with their clinician before starting therapy.

To place an order, submit an enquiry on the Metronidazol Arena product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metronidazol Arena contains the same active ingredient, metronidazole, as other nitroimidazole products. Differences may lie in manufacturing quality, regulatory compliance, and supply chain reliability. Clinically, efficacy and safety are comparable when used at equivalent doses prescribed by a qualified professional.

Store Metronidazol Arena at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Metronidazol Arena is taken orally, usually with food or a full glass of water to reduce gastrointestinal irritation. The exact administration schedule—such as frequency and duration—must be determined by the prescribing clinician based on the infection being treated.

Serious adverse events, although rare, include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, liver toxicity, and blood dyscrasias. Patients should seek immediate medical attention if they experience neurological symptoms, rash, or signs of organ dysfunction.

Individuals with a known hypersensitivity to metronidazole or other nitroimidazole compounds should avoid the product. Patients with severe hepatic impairment, certain neurological disorders, or those who cannot abstain from alcohol during therapy should discuss alternatives with their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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